West Nile Virus Drug Discovery

by Siew Pheng Lim, Pei-Yong Shi
Published 2013-12-01

Cloning Trap for Signal Peptide Sequences

by Siew Pheng Lim, Alfredo Garzino-Demo
Published 2000-01-01

Editorial: Viral Evasion Mechanisms of the Host Response

by Ricardo Martín Gómez, Ricardo Martín Gómez, Eugenio Antonio Carrera Silva, Jônatas Santos Abrahão, Siew Pheng Lim, Aleem Siddiqui
Published 2020-02-01

Crystal structure of the dengue virus methyltransferase bound to a 5'-capped octameric RNA.

by Li Jian Yap, Dahai Luo, Ka Yan Chung, Siew Pheng Lim, Christophe Bodenreider, Christian Noble, Pei-Yong Shi, Julien Lescar
Published 2010-09-01

Discovery of a non-peptidic inhibitor of west nile virus NS3 protease by high-throughput docking.

by Dariusz Ekonomiuk, Xun-Cheng Su, Kiyoshi Ozawa, Christophe Bodenreider, Siew Pheng Lim, Zheng Yin, Thomas H Keller, David Beer, Viral Patel, Gottfried Otting, Amedeo Caflisch, Danzhi Huang
Published 2009-01-01

2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase.

by Hongping Dong, David C Chang, Maggie Ho Chia Hua, Siew Pheng Lim, Yok Hian Chionh, Fabian Hia, Yie Hou Lee, Petra Kukkaro, Shee-Mei Lok, Peter C Dedon, Pei-Yong Shi
Published 2012-01-01

A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication.

by Yongqian Zhao, Tingjin Sherryl Soh, Jie Zheng, Kitti Wing Ki Chan, Wint Wint Phoo, Chin Chin Lee, Moon Y F Tay, Kunchithapadam Swaminathan, Tobias C Cornvik, Siew Pheng Lim, Pei-Yong Shi, Julien Lescar, Subhash G Vasudevan, Dahai Luo
Published 2015-03-01

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.

by Siew Pheng Lim, Christian Guy Noble, Cheah Chen Seh, Tingjin Sherryl Soh, Abbas El Sahili, Grace Kar Yarn Chan, Julien Lescar, Rishi Arora, Timothy Benson, Shahul Nilar, Ujjini Manjunatha, Kah Fei Wan, Hongping Dong, Xuping Xie, Pei-Yong Shi, Fumiaki Yokokawa
Published 2016-08-01

Adjusting the use of glucose-lowering agents in the real-world clinical management of people with type 2 diabetes: A narrative review

by Chan, Siew Pheng, Lim, Lee Ling, Chan, Juliana C. N., Matthews, David R. R.
Published 2023