Optimized Stem Cell Detection Using the DyeCycle-Triggered Side Population Phenotype

by Maximilian Boesch, Dominik Wolf, Sieghart Sopper
Published 2016-01-01

NK Cells in Myeloproliferative Neoplasms (MPN)

by Erin Naismith, Janine Steichen, Sieghart Sopper, Dominik Wolf
Published 2021-08-01

Noncytolytic CD8+ Cell Mediated Antiviral Response Represents a Strong Element in the Immune Response of Simian Immunodeficiency Virus-Infected Long-Term Non-Progressing Rhesus Mac...

by Aneela Javed, Nicole Leuchte, Berit Neumann, Sieghart Sopper, Ulrike Sauermann
Published 2015-01-01

Sitagliptin Accelerates Endothelial Regeneration after Vascular Injury Independent from GLP1 Receptor Signaling

by Friederike Remm, Nicolle Kränkel, Daniela Lener, Daniel J. Drucker, Sieghart Sopper, Christoph Brenner
Published 2018-01-01

The influence of stromal cells and tumor-microenvironment-derived cytokines and chemokines on CD3+CD8+ tumor infiltrating lymphocyte subpopulations

by Stefan Koeck, Johan Kern, Marit Zwierzina, Gabriele Gamerith, Edith Lorenz, Sieghart Sopper, Heinz Zwierzina, Arno Amann
Published 2017-06-01

Immunophenotypic characterization of human T cells after in vitro exposure to different silicone breast implant surfaces.

by Giuseppe Cappellano, Christian Ploner, Susanne Lobenwein, Sieghart Sopper, Paul Hoertnagl, Christina Mayerl, Nikolaus Wick, Gerhard Pierer, Georg Wick, Dolores Wolfram
Published 2018-01-01

The prognostic value of Presepsin for postoperative complications following pancreatic resection: A prospective study.

by Silvia Gasteiger, Florian Primavesi, Peter Werkl, Lucie Dostal, Philipp Gehwolf, Eva Braunwarth, Manuel Maglione, Sieghart Sopper, Dietmar Öfner, Stefan Stättner
Published 2020-01-01

Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness

by Maximilian Boesch, Lucas Onder, Hung-Wei Cheng, Mario Novkovic, Urs Mörbe, Sieghart Sopper, Guenther Gastl, Wolfram Jochum, Thomas Ruhstaller, Michael Knauer, Burkhard Ludewig
Published 2018-04-01

CD8+HLADR+ Regulatory T Cells Change With Aging: They Increase in Number, but Lose Checkpoint Inhibitory Molecules and Suppressive Function

by Stella Lukas Yani, Michael Keller, Franz Leonard Melzer, Birgit Weinberger, Luca Pangrazzi, Sieghart Sopper, Klemens Trieb, Monia Lobina, Valeria Orrù, Edoardo Fiorillo, Francesco Cucca, Beatrix Grubeck-Loebenstein
Published 2018-06-01

Comparative analysis of 10X Chromium vs. BD Rhapsody whole transcriptome single-cell sequencing technologies in complex human tissues

by Stefan Salcher, Isabel Heidegger, Gerold Untergasser, Georgios Fotakis, Alexandra Scheiber, Agnieszka Martowicz, Asma Noureen, Anne Krogsdam, Christoph Schatz, Georg Schäfer, Zlatko Trajanoski, Dominik Wolf, Sieghart Sopper, Andreas Pircher
Published 2024-04-01

13C tracer analysis reveals the landscape of metabolic checkpoints in human CD8+ T cell differentiation and exhaustion

by Alexander Kirchmair, Niloofar Nemati, Giorgia Lamberti, Marcel Trefny, Anne Krogsdam, Anne Krogsdam, Anita Siller, Paul Hörtnagl, Petra Schumacher, Sieghart Sopper, Adolf Sandbichler, Alfred Zippelius, Bart Ghesquière, Bart Ghesquière, Zlatko Trajanoski
Published 2023-10-01

Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade

by Victoria Klepsch, Natascha Hermann-Kleiter, Patricia Do-Dinh, Bojana Jakic, Anne Offermann, Mirjana Efremova, Sieghart Sopper, Dietmar Rieder, Anne Krogsdam, Gabriele Gamerith, Sven Perner, Alexandar Tzankov, Zlatko Trajanoski, Dominik Wolf, Gottfried Baier
Published 2018-04-01

Whole stromal fibroblast signature is linked to specific chemokine and immune infiltration patterns and to improved survival in NSCLC

by Stefan Koeck, Arno Amann, Johan Kern, Marit Zwierzina, Edith Lorenz, Sieghart Sopper, Heinz Zwierzina, Finn Mildner, Martina Sykora, Susanne Sprung, Hubert Hackl, Florian Augustin, Hubert T. Maier, Andreas Pircher, Georg Pall, Dominik Wolf, Gabriele Gamerith
Published 2023-12-01

Smooth Muscle Specific Ablation of CXCL12 in Mice Downregulates CXCR7 Associated with Defective Coronary Arteries and Cardiac Hypertrophy

by Santhosh Kumar Ghadge, Moritz Messner, Herbert Seiringer, Thomas Maurer, Simon Staggl, Tanja Zeller, Christian Müller, Daniela Börnigen, Wolfgang J. Weninger, Stefan H. Geyer, Sieghart Sopper, Anne Krogsdam, Gerhard Pölzl, Axel Bauer, Marc-Michael Zaruba
Published 2021-05-01

Cytotoxic response of tumor-infiltrating lymphocytes of head and neck cancer slice cultures under mitochondrial dysfunction

by Maria do Carmo Greier, Annette Runge, Jozsef Dudas, Roland Hartl, Matthias Santer, Daniel Dejaco, Teresa Bernadette Steinbichler, Julia Federspiel, Christof Seifarth, Marko Konschake, Susanne Sprung, Sieghart Sopper, Avneet Randhawa, Melissa Mayr, Benedikt Gabriel Hofauer, Herbert Riechelmann
Published 2024-03-01

Complex Interplay of Genes Underlies Invasiveness in Fibrosarcoma Progression Model

by Michaela Kripnerová, Hamendra Singh Parmar, Jiří Šána, Alena Kopková, Lenka Radová, Sieghart Sopper, Krzysztof Biernacki, Jan Jedlička, Michaela Kohoutová, Jitka Kuncová, Jan Peychl, Emil Rudolf, Miroslav Červinka, Zbyněk Houdek, Pavel Dvořák, Kateřina Houfková, Martin Pešta, Zdeněk Tůma, Martina Dolejšová, Filip Tichánek, Václav Babuška, Martin Leba, Ondřej Slabý, Jiří Hatina
Published 2021-05-01

Comprehensive characterization of the prostate tumor microenvironment identifies CXCR4/CXCL12 crosstalk as a novel antiangiogenic therapeutic target in prostate cancer

by Isabel Heidegger, Georgios Fotakis, Anne Offermann, Jermaine Goveia, Sophia Daum, Stefan Salcher, Asma Noureen, Hetty Timmer-Bosscha, Georg Schäfer, Annemiek Walenkamp, Sven Perner, Aleksandar Beatovic, Matthieu Moisse, Christina Plattner, Anne Krogsdam, Johannes Haybaeck, Sieghart Sopper, Stefanie Thaler, Markus A. Keller, Helmut Klocker, Zlatko Trajanoski, Dominik Wolf, Andreas Pircher
Published 2022-06-01

Correction to: Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

by Francesca Finotello, Clemens Mayer, Christina Plattner, Gerhard Laschober, Dietmar Rieder, Hubert Hackl, Anne Krogsdam, Zuzana Loncova, Wilfried Posch, Doris Wilflingseder, Sieghart Sopper, Marieke Ijsselsteijn, Thomas P. Brouwer, Douglas Johnson, Yaomin Xu, Yu Wang, Melinda E. Sanders, Monica V. Estrada, Paula Ericsson-Gonzalez, Pornpimol Charoentong, Justin Balko, Noel Filipe da Cunha Carvalho de Miranda, Zlatko Trajanoski
Published 2019-07-01

Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

by Francesca Finotello, Clemens Mayer, Christina Plattner, Gerhard Laschober, Dietmar Rieder, Hubert Hackl, Anne Krogsdam, Zuzana Loncova, Wilfried Posch, Doris Wilflingseder, Sieghart Sopper, Marieke Ijsselsteijn, Thomas P. Brouwer, Douglas Johnson, Yaomin Xu, Yu Wang, Melinda E. Sanders, Monica V. Estrada, Paula Ericsson-Gonzalez, Pornpimol Charoentong, Justin Balko, Noel Filipe da Cunha Carvalho de Miranda, Zlatko Trajanoski
Published 2019-05-01

Single cell immune profiling by mass cytometry of newly diagnosed chronic phase chronic myeloid leukemia treated with nilotinib

by Stein-Erik Gullaksen, Jørn Skavland, Sonia Gavasso, Vinko Tosevski, Krzysztof Warzocha, Claudia Dumrese, Augustin Ferrant, Tobias Gedde-Dahl, Andrzej Hellmann, Jeroen Janssen, Boris Labar, Alois Lang, Waleed Majeed, Georgi Mihaylov, Jesper Stentoft, Leif Stenke, Josef Thaler, Noortje Thielen, Gregor Verhoef, Jaroslava Voglova, Gert Ossenkoppele, Andreas Hochhaus, Henrik Hjorth-Hansen, Satu Mustjoki, Sieghart Sopper, Francis Giles, Kimmo Porkka, Dominik Wolf, Bjørn Tore Gjertsen
Published 2017-08-01