Classification of VUS and unclassified variants in BRCA1 BRCT repeats by molecular dynamics simulation

by Siddharth Sinha, San Ming Wang
Published 2020-01-01

Coupled Genome-Wide DNA Methylation and Transcription Analysis Identified Rich Biomarkers and Drug Targets in Triple-Negative Breast Cancer

by Maoni Guo, Siddharth Sinha, San Ming Wang
Published 2019-11-01

RBD Double Mutations of SARS-CoV-2 Strains Increase Transmissibility through Enhanced Interaction between RBD and ACE2 Receptor

by Siddharth Sinha, Benjamin Tam, San Ming Wang
Published 2021-12-01

Applications of Molecular Dynamics Simulation in Protein Study

by Siddharth Sinha, Benjamin Tam, San Ming Wang
Published 2022-08-01

Combining Ramachandran plot and molecular dynamics simulation for structural-based variant classification: Using TP53 variants as model

by Benjamin Tam, Siddharth Sinha, San Ming Wang
Published 2020-01-01

Clinical trial data reuse – overcoming complexities in trial design and data sharing

by Toby Wilkinson, Siddharth Sinha, Niels Peek, Nophar Geifman
Published 2019-08-01

BRCA1 and BRCA2 Variation in Taiwanese General Population and the Cancer Cohort

by Jiasheng Chian, Siddharth Sinha, Zixin Qin, San Ming Wang
Published 2021-06-01

Comprehensive Identification of Deleterious <i>TP53</i> Missense VUS Variants Based on Their Impact on TP53 Structural Stability

by Benjamin Tam, Siddharth Sinha, Zixin Qin, San Ming Wang
Published 2021-10-01

Classification of MLH1 Missense VUS Using Protein Structure-Based Deep Learning-Ramachandran Plot-Molecular Dynamics Simulations Method

by Benjamin Tam, Zixin Qin, Bojin Zhao, Siddharth Sinha, Chon Lok Lei, San Ming Wang
Published 2024-01-01

High fidelity simulation of the endoscopic transsphenoidal approach: Validation of the UpSurgeOn TNS Box

by Nicola Newall, Nicola Newall, Danyal Z. Khan, Danyal Z. Khan, John G. Hanrahan, John G. Hanrahan, James Booker, James Booker, Anouk Borg, Joseph Davids, Federico Nicolosi, Siddharth Sinha, Siddharth Sinha, Neil Dorward, Hani J. Marcus, Hani J. Marcus
Published 2022-12-01

Highly diversified core promoters in the human genome and their effects on gene expression and disease predisposition

by Hemant Gupta, Khyati Chandratre, Siddharth Sinha, Teng Huang, Xiaobing Wu, Jian Cui, Michael Q. Zhang, San Ming Wang
Published 2020-11-01

Using Portuguese BRCA pathogenic variation as a model to study the impact of human admixture on human health

by Stephanie Andaluz, Bojin Zhao, Siddharth Sinha, Philip Naderev Panuringan Lagniton, Diogo Alpuim Costa, Xiaofan Ding, Miguel Brito, San Ming Wang
Published 2024-04-01

Pathogenic variants in human DNA damage repair genes mostly arose in recent human history

by Bojin Zhao, Jiaheng Li, Siddharth Sinha, Zixin Qin, Si Hoi Kou, Fengxia Xiao, Huijun Lei, Tianhui Chen, Wenming Cao, Xiaofan Ding, San Ming Wang
Published 2024-04-01

Spinal intradural arachnoid cysts - A multicentre case series assessing management and outcomes

by James Bartram, Asfand Baig Mirza, Siddharth Sinha, Timothy Boardman, Axumawi Gebreyohanes, Amisha Vastani, Edward Dyson, Vittorio Russo, David Choi, Ahilan Kailaya-Vasan, Gordan Grahovac
Published 2021-01-01

Mapping patient education encounters in elective surgery: a cohort study and cross-sectional survey

by David Rowland, Siddharth Sinha, Hani J Marcus, Jack Penn, Parag Sayal, Chan Hee Koh, James Booker, Nicola Newall, John G Hanrahan, Simon C Williams
Published 2024-05-01

Impact of Tubular retractor Associated diffusion changes in Minimally Invasive Parafascicular Surgery for Deep-seated Lesions

by Mariam Awan, Aya Elshalakany, Dimitrios Kalaitzoglou, Siddharth Sinha, Nida Kalyal, Mathew Gallagher, Daniel Richardson, Ahmed Abougamil, Melissa Silva, Anna Oviedova, Sabina Patel, Ana Mirallave-Pescador, Cristina Bleil, Bassel Zebian, Richard Gullan, Keyoumars Ashkan, Francesco Vergani, Ranjeev Bhangoo, José Pedro Lavrador
Published 2023-01-01

UK Chiari 1 Study: protocol for a prospective, observational, multicentre study

by Joseph Merola, Julie Woodfield, Linda D’Antona, Richard Edwards, Jothy Kandasamy, Paul Leach, Mano Shanmuganathan, Saurabh Sinha, Dominic Thompson, Lewis Thorne, Ahmed Toma, Shungu Ushewokunze, Laurence Watkins, James Stewart, Angelos G Kolias, Jayaratnam Jayamohan, Pasquale Gallo, Navneet Singh, Ashwin Kumaria, Rhannon Lobo, Marianne Hare, Ardalan Zolnourian, Rory J Piper, Daniel Thompson, Greg James, Georgios Tsermoulas, Rosa Sun, William B Lo, Wai Cheong Soon, Babar Vaqas, Muhammad Kamal, Fardad T Afshari, Edward W Dyson, Rodney Laing, Aabir Chakraborty, Adrian Casey, Adriana Baritchii, Alexandros Vyziotis, Ali Nader-Sephai, Alistair Jenkins, Amin Andalib, Anan Shtaya, Andrew Alalade, Andrew Brodbelt, Arup Ray, Asfand Baig Mirza, Aswin Chari, Barrie White, Benedetta Pettorini, Chandrasekaran Kaliaperumal, Danyal Khan, Dardis Ronan, David Choi, David Rowland, Edward Jerome St George, Eleni Maratos, Grainne McKenna, Hani Marcus, Hasan Asif, Hugo Layard Horsfall, Ian Kamaly-Asl, Ibrahim Jalloh, Jawad Naushahi, Joe M Das, John Duddy, Jonathan Funnell, Justyna Ekert, Kevin Tsang, Lizkerry Odeh, Makinah Haq, Mansoor Foroughi, Mark Nowell, Matthew Boissaud-Cooke, Melissa Gough, Menaka Paranathala, Micaela Uberti, Michael Cearns, Milan Makwana, Milo Hollingworth, Ming Yao Chong, Musa China, Nadia Salloum, Nicholas Haden, Nikolaos Tzerakis, Oscar MacCormac, Peter McGarrity, Rudrajit Kanjilal, Ryan Waters, Saeed Kayhanian, Samuel Jeffery, Setthasorn Zhi Yang Ooi, Shabin Joshi, Shady Elsayed, Shafqat Bukhari, Shailendra Magdum, Siddharth Sinha, Simon Lammy, Stana Bojanic, Stewart Griffiths, Thomas Carroll, Vasileios Raptopoulos, Vivek Josan, Yasir Chowdhury, Zubair Tahir
Published 2021-04-01