20902 Elucidation of Cardioprotective Mechanisms via Human Models of Chemotherapy-Induced Cardiotoxicity

by Nnamdi Uche, Qiang Dai, Shuping Lai, Ivor Benjamin
Published 2021-03-01

Carvedilol Phenocopies PGC-1α Overexpression to Alleviate Oxidative Stress, Mitochondrial Dysfunction and Prevent Doxorubicin-Induced Toxicity in Human iPSC-Derived Cardiomyocytes

by Nnamdi Uche, Qiang Dai, Shuping Lai, Kurt Kolander, Mai Thao, Elizabeth Schibly, Xavier Sendaydiego, Jacek Zielonka, Ivor J. Benjamin
Published 2023-08-01

Functional and Pharmacological Analysis of Cardiomyocytes Differentiated from Human Peripheral Blood Mononuclear-Derived Pluripotent Stem Cells

by Michael Riedel, Chuanchau J. Jou, Shuping Lai, Robert L. Lux, Alonso P. Moreno, Kenneth W. Spitzer, Elizabeth Christians, Martin Tristani-Firouzi, Ivor J. Benjamin
Published 2014-07-01

Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins

by Gary S. Coombs, Jose L. Rios-Monterrosa, Shuping Lai, Qiang Dai, Ashley C. Goll, Margaret R. Ketterer, Maria F. Valdes, Nnamdi Uche, Ivor J. Benjamin, Lori L. Wallrath
Published 2021-12-01

Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection

by Katie A. Mitzelfelt, Chris McDermott-Roe, Michael N. Grzybowski, Maribel Marquez, Chieh-Ti Kuo, Michael Riedel, Shuping Lai, Melinda J. Choi, Kurt D. Kolander, Daniel Helbling, David P. Dimmock, Michele A. Battle, Chuanchau J. Jou, Martin Tristani-Firouzi, James W. Verbsky, Ivor J. Benjamin, Aron M. Geurts
Published 2017-03-01

Collagen‐Specific HSP47+ Myofibroblasts and CD163+ Macrophages Identify Profibrotic Phenotypes in Deceased Hearts With SARS‐CoV‐2 Infections

by Andrii Puzyrenko, Elizabeth R. Jacobs, Nathan Padilla, Adam Devine, Michael Aljadah, Benjamin N. Gantner, Amy Y. Pan, Shuping Lai, Qiang Dai, Jason C. Rubenstein, Paula E. North, Pippa M. Simpson, Rodney E. Willoughby, Caitlin C. O'Meara, Michael A. Flinn, John W. Lough, El‐Sayed H. Ibrahim, Ze Zheng, Yunguang Sun, Juan Felix, Bryan C. Hunt, Gracious Ross, Hallgeir Rui, Ivor J. Benjamin
Published 2023-02-01

A Small-Molecule Inhibitor of PIM Kinases as a Potential Treatment for Urothelial Carcinomas

by Jason M. Foulks, Kent J. Carpenter, Bai Luo, Yong Xu, Anna Senina, Rebecca Nix, Ashley Chan, Adrianne Clifford, Marcus Wilkes, David Vollmer, Benjamin Brenning, Shannon Merx, Shuping Lai, Michael V. McCullar, Koc-Kan Ho, Daniel J. Albertson, Lee T. Call, Jared J. Bearss, Sheryl Tripp, Ting Liu, Bret J. Stephens, Alexis Mollard, Steven L. Warner, David J. Bearss, Steven B. Kanner
Published 2014-05-01

The history and geographic distribution of a KCNQ1 atrial fibrillation risk allele

by Shannon Hateley, Angelica Lopez-Izquierdo, Chuanchau J. Jou, Scott Cho, Joshua G. Schraiber, Shiya Song, Colin T. Maguire, Natalia Torres, Michael Riedel, Neil E. Bowles, Cammon B. Arrington, Brett J. Kennedy, Susan P. Etheridge, Shuping Lai, Chase Pribble, Lindsay Meyers, Derek Lundahl, Jake Byrnes, Julie M. Granka, Christopher A. Kauffman, Gordon Lemmon, Steven Boyden, W. Scott Watkins, Mary Anne Karren, Stacey Knight, J. Brent Muhlestein, John F. Carlquist, Jeffrey L. Anderson, Kenneth G. Chahine, Khushi U. Shah, Catherine A. Ball, Ivor J. Benjamin, Mark Yandell, Martin Tristani-Firouzi
Published 2021-11-01