1426 Combination with BCA101 improves the efficacy of KRAS-G12C inhibitor and overcomes G12C inhibitor-induced resistance in lung and colon cancer cell lines

by Rachel Salazar, Reshmi Nair, Pradip Nair, Veena Somasundaram, Shiv Ram Krishn
Published 2023-11-01

Mechanistic and Functional Shades of Mucins and Associated Glycans in Colon Cancer

by Ramesh Pothuraju, Shiv Ram Krishn, Shailendra K. Gautam, Priya Pai, Koelina Ganguly, Sanjib Chaudhary, Satyanarayana Rachagani, Sukhwinder Kaur, Surinder K. Batra
Published 2020-03-01

Acinar transformed ductal cells exhibit differential mucin expression in a tamoxifen-induced pancreatic ductal adenocarcinoma mouse model

by Kavita Mallya, Dhanya Haridas, Parthasarathy Seshacharyulu, Ramesh Pothuraju, Wade M. Junker, Shiv Ram Krishn, Sakthivel Muniyan, Raghupathy Vengoji, Surinder K. Batra, Satyanarayana Rachagani
Published 2020-09-01

Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells

by Shiv Ram Krishn, Vaughn Garcia, Nicole M. Naranjo, Fabio Quaglia, Christopher D. Shields, Maisha A. Harris, Andrew V. Kossenkov, Qin Liu, Eva Corey, Dario C. Altieri, Lucia R. Languino
Published 2022-12-01

Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance

by Ramesh Pothuraju, Satyanarayana Rachagani, Shiv Ram Krishn, Sanjib Chaudhary, Rama Krishna Nimmakayala, Jawed A. Siddiqui, Koelina Ganguly, Imayavaramban Lakshmanan, Jesse L. Cox, Kavita Mallya, Sukhwinder Kaur, Surinder K. Batra
Published 2020-02-01

Tumor-Derived Extracellular Vesicles Require β1 Integrins to Promote Anchorage-Independent Growth

by Rachel M. DeRita, Aejaz Sayeed, Vaughn Garcia, Shiv Ram Krishn, Christopher D. Shields, Srawasti Sarker, Andrea Friedman, Peter McCue, Sudheer Kumar Molugu, Ulrich Rodeck, Adam P. Dicker, Lucia R. Languino
Published 2019-04-01

Small extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells

by Fabio Quaglia, Shiv Ram Krishn, George G. Daaboul, Srawasti Sarker, Raffaella Pippa, Josep Domingo-Domenech, Gaurav Kumar, Paolo Fortina, Peter McCue, William K. Kelly, Himisha Beltran, Qin Liu, Lucia R. Languino
Published 2020-01-01

Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression.

by Fabio Quaglia, Shiv Ram Krishn, Yanqing Wang, David W Goodrich, Peter McCue, Andrew V Kossenkov, Amy C Mandigo, Karen E Knudsen, Paul H Weinreb, Eva Corey, William K Kelly, Lucia R Languino
Published 2021-01-01

The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis

by Shiv Ram Krishn, Israa Salem, Fabio Quaglia, Nicole M. Naranjo, Ekta Agarwal, Qin Liu, Srawasti Sarker, Jessica Kopenhaver, Peter A. McCue, Paul H. Weinreb, Shelia M. Violette, Dario C. Altieri, Lucia R. Languino
Published 2020-01-01

The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancer

by Fabio Quaglia, Shiv Ram Krishn, Khalid Sossey-Alaoui, Priyanka Shailendra Rana, Elzbieta Pluskota, Pyung Hun Park, Christopher D. Shields, Stephen Lin, Peter McCue, Andrew V. Kossenkov, Yanqing Wang, David W. Goodrich, Sheng-Yu Ku, Himisha Beltran, William K. Kelly, Eva Corey, Maja Klose, Christine Bandtlow, Qin Liu, Dario C. Altieri, Edward F. Plow, Lucia R. Languino
Published 2022-11-01