Patient-Derived Induced Pluripotent Stem Cells and Organoids for Modeling Alpha Synuclein Propagation in Parkinson's Disease

by Yong Hui Koh, Yong Hui Koh, Li Yi Tan, Shi-Yan Ng, Shi-Yan Ng, Shi-Yan Ng, Shi-Yan Ng
Published 2018-11-01

Remodeling of astrocyte secretome in amyotrophic lateral sclerosis: uncovering novel targets to combat astrocyte-mediated toxicity

by Winanto Ng, Shi-Yan Ng
Published 2022-12-01

Replacing what’s lost: a new era of stem cell therapy for Parkinson’s disease

by Yong Fan, Winanto, Shi-Yan Ng
Published 2020-01-01

Defined hydrogels for spinal cord organoids: challenges and potential applications

by Wai Hon Chooi, Yuewen Wu, Shi-Yan Ng
Published 2024-01-01

Spinal cord organoids add an extra dimension to traditional motor neuron cultures

by Winanto, Zi-Jian Khong, Jin-Hui Hor, Shi-Yan Ng
Published 2019-01-01

Deciphering lipid dysregulation in ALS: from mechanisms to translational medicine

by Ira Agrawal, Yong Shan Lim, Shi-Yan Ng, Shuo-Chien Ling
Published 2022-11-01

Modulating neuroinflammation through molecular, cellular and biomaterial‐based approaches to treat spinal cord injury

by Cheryl Yi‐Pin Lee, Wai Hon Chooi, Shi‐Yan Ng, Sing Yian Chew
Published 2023-03-01

Wnt/β-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes

by Yong Fan, Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Nicole Min Qian Pek, Jin Hui Hor, Shi-Yan Ng, Boon-Seng Soh
Published 2018-12-01

Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases

by Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Ying Chen, Yuin-Han Loh, Omer An, Henry He Yang, Veerabrahma Pratap Seshachalam, Judice L. Y. Koh, Woon-Khiong Chan, Shi Yan Ng, Boon Seng Soh
Published 2022-12-01

Correction: Corrigendum: Endothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells

by Boon-Seng Soh, Shi-Yan Ng, Hao Wu, Kristina Buac, Joo-Hye C. Park, Xiaojun Lian, Jiejia Xu, Kylie S Foo, Ulrika Felldin, Xiaobing He, Massimo Nichane, Henry Yang, Lie Bu, Ronald A Li, Bing Lim, Kenneth R Chien
Published 2016-07-01

Endothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells

by Boon-Seng Soh, Shi-Yan Ng, Hao Wu, Kristina Buac, Joo-Hye C. Park, Xiaojun Lian, Jiejia Xu, Kylie S. Foo, Ulrika Felldin, Xiaobing He, Massimo Nichane, Henry Yang, Lei Bu, Ronald A. Li, Bing Lim, Kenneth R. Chien
Published 2016-03-01

Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease

by Natalia Rodriguez-Muela, Nadia K. Litterman, Erika M. Norabuena, Jesse L. Mull, Maria José Galazo, Chicheng Sun, Shi-Yan Ng, Nina R. Makhortova, Andrew White, Maureen M. Lynes, Wendy K. Chung, Lance S. Davidow, Jeffrey D. Macklis, Lee L. Rubin
Published 2017-02-01

FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons

by Wan Yun Ho, Li-Ling Chak, Jin-Hui Hor, Fujia Liu, Sandra Diaz-Garcia, Jer-Cherng Chang, Emma Sanford, Maria J. Rodriguez, Durgadevi Alagappan, Su Min Lim, Yik-Lam Cho, Yuji Shimizu, Alfred Xuyang Sun, Sheue-Houy Tyan, Edward Koo, Seung Hyun Kim, John Ravits, Shi-Yan Ng, Katsutomo Okamura, Shuo-Chien Ling
Published 2023-11-01

METABOLIC PROFILING OF MOTOR NEURONS DERIVED FROM PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS

by HOR JIN HUI
Published 2020

Using intracellular markers to identify a novel set of surface markers for live cell purification from a heterogeneous hIPSC culture

by Paik, Elizabeth J., O’Neil, Alison L., Ng, Shi-Yan, Sun, Chicheng, Rubin, Lee L.
Published 2018