OTUD3 suppresses the mTORC1 signaling by deubiquitinating KPTN

by Jiatao Li, Dan Yang, Yan Lin, Wei Xu, Shi-min Zhao, Chenji Wang
Published 2024-01-01

Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis

by Sha Xu, Hui Tao, Wei Cao, Li Cao, Yan Lin, Shi-Min Zhao, Wei Xu, Jing Cao, Jian-Yuan Zhao
Published 2021-02-01

APC/CCDH1 synchronizes ribose-5-phosphate levels and DNA synthesis to cell cycle progression

by Yang Li, Cui-Fang Yao, Fu-Jiang Xu, Yuan-Yuan Qu, Jia-Tao Li, Yan Lin, Zhong-Lian Cao, Peng-Cheng Lin, Wei Xu, Shi-Min Zhao, Jian-Yuan Zhao
Published 2019-06-01

PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase

by Gommaar D’Hulst, Inés Soro-Arnaiz, Evi Masschelein, Koen Veys, Gillian Fitzgerald, Benoit Smeuninx, Sunghoon Kim, Louise Deldicque, Bert Blaauw, Peter Carmeliet, Leigh Breen, Peppi Koivunen, Shi-Min Zhao, Katrien De Bock
Published 2020-01-01

Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk

by Xiao-Hui Wang, Sha Xu, Xiang-Yu Zhou, Rui Zhao, Yan Lin, Jing Cao, Wei-Dong Zang, Hui Tao, Wei Xu, Ming-Qing Li, Shi-Min Zhao, Li-Ping Jin, Jian-Yuan Zhao
Published 2021-06-01

A new strategy to produce a defensin: stable production of mutated NP-1 in nitrate reductase-deficient Chlorella ellipsoidea.

by Li-Li Bai, Wei-Bo Yin, Yu-Hong Chen, Li-Li Niu, Yong-Ru Sun, Shi-Min Zhao, Fu-Quan Yang, Richard R-C Wang, Qing Wu, Xiang-Qi Zhang, Zan-Min Hu
Published 2013-01-01

Mitochondrial STAT5A promotes metabolic remodeling and the Warburg effect by inactivating the pyruvate dehydrogenase complex

by Liang Zhang, Jianong Zhang, Yan Liu, Pingzhao Zhang, Ji Nie, Rui Zhao, Qin Shi, Huiru Sun, Dongyue Jiao, Yingji Chen, Xiaying Zhao, Yan Huang, Yao Li, Jian-Yuan Zhao, Wei Xu, Shi-Min Zhao, Chenji Wang
Published 2021-06-01

Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer.

by Xiaofeng Jin, Jie Wang, Kun Gao, Pingzhao Zhang, Longfang Yao, Yan Tang, Lisha Tang, Jian Ma, Jiantao Xiao, Enceng Zhang, Jie Zhu, Bin Zhang, Shi-Min Zhao, Yao Li, Shancheng Ren, Haojie Huang, Long Yu, Chenji Wang
Published 2017-04-01

Nuclear ATR lysine-tyrosylation protects against heart failure by activating DNA damage response

by Rui Zhao, Ke Cai, Jing-Jing Yang, Qian Zhou, Wei Cao, Jie Xiang, Yi-Hui Shen, Lei-Lei Cheng, Wei-Dong Zang, Yan Lin, Yi-Yuan Yuan, Wei Xu, Hui Tao, Shi-Min Zhao, Jian-Yuan Zhao
Published 2023-04-01

Colonic Lysine Homocysteinylation Induced by High-Fat Diet Suppresses DNA Damage Repair

by Dan Wang, Rui Zhao, Yuan-Yuan Qu, Xin-Yu Mei, Xuan Zhang, Qian Zhou, Yang Li, Shao-Bo Yang, Zhi-Gui Zuo, Yi-Ming Chen, Yan Lin, Wei Xu, Chao Chen, Shi-Min Zhao, Jian-Yuan Zhao
Published 2018-10-01

Author Correction: Ketogenic diet-produced β-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy

by Ya-Nan Qiao, Lei Li, Song-Hua Hu, Yuan-Xin Yang, Zhen-Zhen Ma, Lin Huang, Yan-Peng An, Yi-Yuan Yuan, Yan Lin, Wei Xu, Yao Li, Peng-Cheng Lin, Jing Cao, Jian-Yuan Zhao, Shi-Min Zhao
Published 2024-04-01

Ketogenic diet-produced β-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy

by Ya-Nan Qiao, Lei Li, Song-Hua Hu, Yuan-Xin Yang, Zhen-Zhen Ma, Lin Huang, Yan-Peng An, Yi-Yuan Yuan, Yan Lin, Wei Xu, Yao Li, Peng-Cheng Lin, Jing Cao, Jian-Yuan Zhao, Shi-Min Zhao
Published 2024-02-01

Prostate Cancer-associated SPOP mutations enhance cancer cell survival and docetaxel resistance by upregulating Caprin1-dependent stress granule assembly

by Qing Shi, Yasheng Zhu, Jian Ma, Kun Chang, Dongling Ding, Yang Bai, Kun Gao, Pingzhao Zhang, Ren Mo, Kai Feng, Xiaying Zhao, Liang Zhang, Huiru Sun, Dongyue Jiao, Yingji Chen, Yinghao Sun, Shi-min Zhao, Haojie Huang, Yao Li, Shancheng Ren, Chenji Wang
Published 2019-11-01

Targeting mTORC2/HDAC3 Inhibits Stemness of Liver Cancer Cells Against Glutamine Starvation

by Hui‐Lu Zhang, Ping Chen, He‐Xin Yan, Gong‐Bo Fu, Fei‐Fei Luo, Jun Zhang, Shi‐Min Zhao, Bo Zhai, Jiang‐Hong Yu, Lin Chen, Hao‐Shu Cui, Jian Chen, Shuai Huang, Jun Zeng, Wei Xu, Hong‐Yang Wang, Jie Liu
Published 2022-07-01

Phenylalanine impairs insulin signaling and inhibits glucose uptake through modification of IRβ

by Qian Zhou, Wan-Wan Sun, Jia-Cong Chen, Hui-Lu Zhang, Jie Liu, Yan Lin, Peng-Cheng Lin, Bai-Xing Wu, Yan-Peng An, Lin Huang, Wen-Xing Sun, Xin-Wen Zhou, Yi-Ming Li, Yi-Yuan Yuan, Jian-Yuan Zhao, Wei Xu, Shi-Min Zhao
Published 2022-07-01

SPOP mutation induces DNA methylation via stabilizing GLP/G9a

by Jianong Zhang, Kun Gao, Hongyan Xie, Dejie Wang, Pingzhao Zhang, Ting Wei, Yuqian Yan, Yunqian Pan, Wenbin Ye, Huifen Chen, Qing Shi, Yao Li, Shi-min Zhao, Xiaonan Hou, Saravut J. Weroha, Yuzhuo Wang, Jun Zhang, R. Jeffrey Karnes, Housheng Hansen He, Liguo Wang, Chenji Wang, Haojie Huang
Published 2021-09-01

Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients

by Ya-Kun Zhang, Yuan-Yuan Qu, Yan Lin, Xiao-Hui Wu, Hou-Zao Chen, Xu Wang, Kai-Qiang Zhou, Yun Wei, Fushen Guo, Cui-Fang Yao, Xia-Di He, Li-Xia Liu, Chen Yang, Zong-Yuan Guan, Shi-Dong Wang, Jianyuan Zhao, De-Pei Liu, Shi-Min Zhao, Wei Xu
Published 2017-09-01