Accumulation of Linoleic Acid by Altered Peroxisome Proliferator-Activated Receptor-α Signaling Is Associated with Age-Dependent Hepatocarcinogenesis in <i>Ppara</i> Transgenic Mic...

by Xiaoyang Zhu, Qing Liu, Andrew D. Patterson, Arun K. Sharma, Shantu G. Amin, Samuel M. Cohen, Frank J. Gonzalez, Jeffrey M. Peters
Published 2023-08-01

Characterization of Anticancer Effects of the Analogs of DJ4, a Novel Selective Inhibitor of ROCK and MRCK Kinases

by Vijay Pralhad Kale, Jeremy A. Hengst, Arati K. Sharma, Upendarrao Golla, Sinisa Dovat, Shantu G. Amin, Jong K. Yun, Dhimant H. Desai
Published 2023-07-01

Glycine‐β‐muricholic acid antagonizes the intestinal farnesoid X receptor–ceramide axis and ameliorates NASH in mice

by Jie Jiang, Yuandi Ma, Yameng Liu, Dasheng Lu, Xiaoxia Gao, Kristopher W. Krausz, Dhimant Desai, Shantu G. Amin, Andrew D. Patterson, Frank J. Gonzalez, Cen Xie
Published 2022-12-01

Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity

by Fangcong Dong, Fuhua Hao, Iain A. Murray, Philip B. Smith, Imhoi Koo, Alyssa M. Tindall, Penny M. Kris-Etherton, Krishne Gowda, Shantu G. Amin, Andrew D. Patterson, Gary H. Perdew
Published 2020-11-01

Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites

by Dhwani Patel, Iain A. Murray, Fangcong Dong, Andrew J. Annalora, Krishne Gowda, Denise M. Coslo, Jacek Krzeminski, Imhoi Koo, Fuhua Hao, Shantu G. Amin, Craig B. Marcus, Andrew D. Patterson, Gary H. Perdew
Published 2023-08-01

Contribution of Circulating Host and Microbial Tryptophan Metabolites Toward Ah Receptor Activation

by Ethan W Morgan, Fangcong Dong, Andrew J Annalora, Iain A Murray, Trenton Wolfe, Reece Erickson, Krishne Gowda, Shantu G Amin, Kristina S Petersen, Penny M Kris-Etherton, Craig B Marcus, Seth T Walk, Andrew D Patterson, Gary H Perdew
Published 2023-07-01