Single Cell Analysis of Endothelial Cells Identified Organ-Specific Molecular Signatures and Heart-Specific Cell Populations and Molecular Features

by Wei Feng, Lyuqin Chen, Lyuqin Chen, Patricia K. Nguyen, Patricia K. Nguyen, Patricia K. Nguyen, Sean M. Wu, Sean M. Wu, Sean M. Wu, Guang Li
Published 2019-11-01

Platypnea-Orthodeoxia Syndrome in Two Previously Healthy Adults: A Case-based Review

by Leon M. Ptaszek, Fidencio Saldana, Igor F. Palacios, Sean M. Wu
Published 2009-01-01

Genome Editing Redefines Precision Medicine in the Cardiovascular Field

by Elda Dzilic, Harald Lahm, Martina Dreßen, Marcus-André Deutsch, Rüdiger Lange, Sean M. Wu, Markus Krane, Stefanie A. Doppler
Published 2018-01-01

Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes.

by Laura Tarnawski, Xiaojie Xian, Gustavo Monnerat, Iain C Macaulay, Daniela Malan, Andrew Borgman, Sean M Wu, Bernd K Fleischmann, Stefan Jovinge
Published 2015-01-01

Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-5

by Norika Liu, Naofumi Kawahira, Yasuhiro Nakashima, Haruko Nakano, Akiyasu Iwase, Yasunobu Uchijima, Mei Wang, Sean M. Wu, Susumu Minamisawa, Hiroki Kurihara, Atsushi Nakano
Published 2023-09-01

devCellPy is a machine learning-enabled pipeline for automated annotation of complex multilayered single-cell transcriptomic data

by Francisco X. Galdos, Sidra Xu, William R. Goodyer, Lauren Duan, Yuhsin V. Huang, Soah Lee, Han Zhu, Carissa Lee, Nicholas Wei, Daniel Lee, Sean M. Wu
Published 2022-09-01

Myeloid zinc finger 1 (Mzf1) differentially modulates murine cardiogenesis by interacting with an Nkx2.5 cardiac enhancer.

by Stefanie A Doppler, Astrid Werner, Melanie Barz, Harald Lahm, Marcus-André Deutsch, Martina Dreßen, Matthias Schiemann, Bernhard Voss, Serge Gregoire, Rajarajan Kuppusamy, Sean M Wu, Rüdiger Lange, Markus Krane
Published 2014-01-01

Combined lineage tracing and scRNA-seq reveals unexpected first heart field predominance of human iPSC differentiation

by Francisco X Galdos, Carissa Lee, Soah Lee, Sharon Paige, William Goodyer, Sidra Xu, Tahmina Samad, Gabriela V Escobar, Adrija Darsha, Aimee Beck, Rasmus O Bak, Matthew H Porteus, Sean M Wu
Published 2023-06-01

Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function

by Alexa Wnorowski, Arun Sharma, Haodong Chen, Haodi Wu, Ning-Yi Shao, Nazish Sayed, Chun Liu, Stefanie Countryman, Louis S. Stodieck, Kathleen H. Rubins, Sean M. Wu, Peter H.U. Lee, Joseph C. Wu
Published 2019-12-01

Myocardial Disease and Long-Distance Space Travel: Solving the Radiation Problem

by Manon Meerman, Manon Meerman, Tom C. L. Bracco Gartner, Tom C. L. Bracco Gartner, Jan Willem Buikema, Jan Willem Buikema, Sean M. Wu, Sailay Siddiqi, Carlijn V. C. Bouten, K. Jane Grande-Allen, Willem J. L. Suyker, Jesper Hjortnaes, Jesper Hjortnaes
Published 2021-02-01

In vivo visualization and molecular targeting of the cardiac conduction system

by William R. Goodyer, Benjamin M. Beyersdorf, Lauren Duan, Nynke S. van den Berg, Sruthi Mantri, Francisco X. Galdos, Nazan Puluca, Jan W. Buikema, Soah Lee, Darren Salmi, Elise R. Robinson, Stephan Rogalla, Dillon P. Cogan, Chaitan Khosla, Eben L. Rosenthal, Sean M. Wu
Published 2022-10-01

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis

by J. Travis Hinson, Anant Chopra, Andre Lowe, Calvin C. Sheng, Rajat M. Gupta, Rajarajan Kuppusamy, John O'Sullivan, Glenn Rowe, Hiroko Wakimoto, Joshua Gorham, Kehan Zhang, Kiran Musunuru, Robert E. Gerszten, Sean M. Wu, Christopher S. Chen, Jonathan G. Seidman, Christine E. Seidman
Published 2016-12-01

CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes

by Orlando Chirikian, William R. Goodyer, Elda Dzilic, Vahid Serpooshan, Jan W. Buikema, Wesley McKeithan, HaoDi Wu, Guang Li, Soah Lee, Markus Merk, Francisco Galdos, Aimee Beck, Alexandre J. S. Ribeiro, Sharon Paige, Mark Mercola, Joseph C. Wu, Beth L. Pruitt, Sean M. Wu
Published 2021-02-01

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis

by J. Travis Hinson, Anant Chopra, Andre Lowe, Calvin C. Sheng, Rajat M. Gupta, Rajarajan Kuppusamy, John O’Sullivan, Glenn Rowe, Hiroko Wakimoto, Joshua Gorham, Michael A. Burke, Kehan Zhang, Kiran Musunuru, Robert E. Gerszten, Sean M. Wu, Christopher S. Chen, Jonathan G. Seidman, Christine E. Seidman
Published 2017-06-01

Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes

by Renee G.C. Maas, Soah Lee, Magdalena Harakalova, Christian J.B. Snijders Blok, William R. Goodyer, Jesper Hjortnaes, Pieter A.F.M. Doevendans, Linda W. Van Laake, Jolanda van der Velden, Folkert W. Asselbergs, Joseph C. Wu, Joost P.G. Sluijter, Sean M. Wu, Jan W. Buikema
Published 2021-03-01

Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy

by Kenichi Kimura, Astrid Ooms, Kathrin Graf-Riesen, Maithreyan Kuppusamy, Andreas Unger, Julia Schuld, Jan Daerr, Achim Lother, Caroline Geisen, Lutz Hein, Satoru Takahashi, Guang Li, Wilhelm Röll, Wilhelm Bloch, Peter F. M. van der Ven, Wolfgang A. Linke, Sean M. Wu, Pitter F. Huesgen, Jörg Höhfeld, Dieter O. Fürst, Bernd K. Fleischmann, Michael Hesse
Published 2021-06-01

Identification of a hybrid myocardial zone in the mammalian heart after birth

by Xueying Tian, Yan Li, Lingjuan He, Hui Zhang, Xiuzhen Huang, Qiaozhen Liu, Wenjuan Pu, Libo Zhang, Yi Li, Huan Zhao, Zhifu Wang, Jianhong Zhu, Yu Nie, Shengshou Hu, David Sedmera, Tao P. Zhong, Ying Yu, Li Zhang, Yan Yan, Zengyong Qiao, Qing-Dong Wang, Sean M. Wu, William T. Pu, Robert H. Anderson, Bin Zhou
Published 2017-07-01