Considering the possibilities and pitfalls of Generative Pre-trained Transformer 3 (GPT-3) in healthcare delivery

by Diane M. Korngiebel, Sean D. Mooney
Published 2021-06-01

Ten simple rules for a community computational challenge.

by Iddo Friedberg, Mark N Wass, Sean D Mooney, Predrag Radivojac
Published 2015-04-01

Evaluation of the secondary use of electronic health records to detect seasonal, holiday-related, and rare events related to traumatic injury and poisoning

by Timothy Bergquist, Vikas Pejaver, Noah Hammarlund, Sean D. Mooney, Stephen J. Mooney
Published 2020-01-01

Data science in clinical and translational research: Improving the health of the data to knowledge pipeline

by Christopher J. Lindsell, Gina-Maria Pomann, Robert A. Oster, Sean D. Mooney, Felicity T. Enders
Published 2021-01-01

A Multifaceted benchmarking of synthetic electronic health record generation models

by Chao Yan, Yao Yan, Zhiyu Wan, Ziqi Zhang, Larsson Omberg, Justin Guinney, Sean D. Mooney, Bradley A. Malin
Published 2022-12-01

The Loss and Gain of Functional Amino Acid Residues Is a Common Mechanism Causing Human Inherited Disease.

by Jose Lugo-Martinez, Vikas Pejaver, Kymberleigh A Pagel, Shantanu Jain, Matthew Mort, David N Cooper, Sean D Mooney, Predrag Radivojac
Published 2016-08-01

ShareDNA: a smartphone app to facilitate family communication of genetic results

by Chethan Jujjavarapu, Jeevan Anandasakaran, Laura M. Amendola, Cameron Haas, Elizabeth Zampino, Nora B. Henrikson, Gail P. Jarvik, Sean D. Mooney
Published 2021-01-01

New Drosophila Long-Term Memory Genes Revealed by Assessing Computational Function Prediction Methods

by Balint Z. Kacsoh, Stephen Barton, Yuxiang Jiang, Naihui Zhou, Sean D. Mooney, Iddo Friedberg, Predrag Radivojac, Casey S. Greene, Giovanni Bosco
Published 2019-01-01

Pathogenicity and functional impact of non-frameshifting insertion/deletion variation in the human genome.

by Kymberleigh A Pagel, Danny Antaki, AoJie Lian, Matthew Mort, David N Cooper, Jonathan Sebat, Lilia M Iakoucheva, Sean D Mooney, Predrag Radivojac
Published 2019-06-01

Predicting decompression surgery by applying multimodal deep learning to patients’ structured and unstructured health data

by Chethan Jujjavarapu, Pradeep Suri, Vikas Pejaver, Janna Friedly, Laura S. Gold, Eric Meier, Trevor Cohen, Sean D. Mooney, Patrick J. Heagerty, Jeffrey G. Jarvik
Published 2023-01-01

Harnessing Innovative Technologies to Train Nurses in Suicide Safety Planning With Hospitalized Patients: Protocol for Formative and Pilot Feasibility Research

by Doyanne Darnell, Patricia A Areán, Shannon Dorsey, David C Atkins, Michael J Tanana, Tad Hirsch, Sean D Mooney, Edwin D Boudreaux, Katherine Anne Comtois
Published 2021-12-01

Evaluating construct validity of computable acute respiratory distress syndrome definitions in adults hospitalized with COVID-19: an electronic health records based approach

by Neha A. Sathe, Su Xian, F. Linzee Mabrey, David R. Crosslin, Sean D. Mooney, Eric D. Morrell, Kevin Lybarger, Meliha Yetisgen, Gail P. Jarvik, Pavan K. Bhatraju, Mark M. Wurfel
Published 2023-08-01

Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington’s Disease Neural Stem Cells

by Karen L. Ring, Mahru C. An, Ningzhe Zhang, Robert N. O’Brien, Eliana Marisa Ramos, Fuying Gao, Robert Atwood, Barbara J. Bailus, Simon Melov, Sean D. Mooney, Giovanni Coppola, Lisa M. Ellerby
Published 2015-12-01

Inferring the molecular and phenotypic impact of amino acid variants with MutPred2

by Vikas Pejaver, Jorge Urresti, Jose Lugo-Martinez, Kymberleigh A. Pagel, Guan Ning Lin, Hyun-Jun Nam, Matthew Mort, David N. Cooper, Jonathan Sebat, Lilia M. Iakoucheva, Sean D. Mooney, Predrag Radivojac
Published 2020-11-01

Medium-Chain Acyl-CoA Deficiency: Outlines from Newborn Screening, In Silico Predictions, and Molecular Studies

by Serena Catarzi, Anna Caciotti, Janita Thusberg, Rodolfo Tonin, Sabrina Malvagia, Giancarlo la Marca, Elisabetta Pasquini, Catia Cavicchi, Lorenzo Ferri, Maria A. Donati, Federico Baronio, Renzo Guerrini, Sean D. Mooney, Amelia Morrone
Published 2013-01-01

Postnatal Conditional Deletion of <i>Bcl11b</i> in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington’s Disease

by Sicheng Song, Jordi Creus Muncunill, Carlos Galicia Aguirre, Kizito-Tshitoko Tshilenge, B. Wade Hamilton, Akos A. Gerencser, Houda Benlhabib, Maria-Daniela Cirnaru, Mark Leid, Sean D. Mooney, Lisa M. Ellerby, Michelle E. Ehrlich
Published 2022-09-01

A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease.

by John P Miller, Bridget E Yates, Ismael Al-Ramahi, Ari E Berman, Mario Sanhueza, Eugene Kim, Maria de Haro, Francesco DeGiacomo, Cameron Torcassi, Jennifer Holcomb, Juliette Gafni, Sean D Mooney, Juan Botas, Lisa M Ellerby, Robert E Hughes
Published 2012-01-01

Development and Validation of ARC, a Model for Anticipating Acute Respiratory Failure in Coronavirus Disease 2019 Patients

by Suchi Saria, PhD, Peter Schulam, PhD, Brian J. Yeh, PhD, Daniel Burke, MD, MBA, Sean D. Mooney, PhD, Christine T. Fong, MS, Jacob E. Sunshine, MD, Dustin R. Long, MD, Vikas N. O’Reilly-Shah, MD, PhD
Published 2021-06-01

Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation

by Maria-Daniela Cirnaru, Sicheng Song, Kizito-Tshitoko Tshilenge, Chuhyon Corwin, Justyna Mleczko, Carlos Galicia Aguirre, Houda Benlhabib, Jaroslav Bendl, Pasha Apontes, John Fullard, Jordi Creus-Muncunill, Azadeh Reyahi, Ali M Nik, Peter Carlsson, Panos Roussos, Sean D Mooney, Lisa M Ellerby, Michelle E Ehrlich
Published 2021-10-01

SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells

by Christopher D. Wiley, Su Liu, Chandani Limbad, Anna M. Zawadzka, Jennifer Beck, Marco Demaria, Robert Artwood, Fatouma Alimirah, Jose-Alberto Lopez-Dominguez, Chisaka Kuehnemann, Steven R. Danielson, Natan Basisty, Herbert G. Kasler, Tal Ronnen Oron, Pierre-Yves Desprez, Sean D. Mooney, Bradford W. Gibson, Birgit Schilling, Judith Campisi, Pankaj Kapahi
Published 2019-09-01