Polo-like kinase-dependent phosphorylation of the synaptonemal complex protein SYP-4 regulates double-strand break formation through a negative feedback loop.

by Saravanapriah Nadarajan, Talley J Lambert, Elisabeth Altendorfer, Jinmin Gao, Michael D Blower, Jennifer C Waters, Monica P Colaiácovo
Published 2017-03-01

Chromatin landscape, DSB levels, and cKU-70/80 contribute to patterning of meiotic DSB processing along chromosomes in C. elegans.

by Laura I Lascarez-Lagunas, Marina Martinez-Garcia, Saravanapriah Nadarajan, Brianna N Diaz-Pacheco, Elizaveta Berson, Mónica P Colaiácovo
Published 2023-01-01

Environmentally-relevant exposure to diethylhexyl phthalate (DEHP) alters regulation of double-strand break formation and crossover designation leading to germline dysfunction in C...

by Luciann Cuenca, Nara Shin, Laura I Lascarez-Lagunas, Marina Martinez-Garcia, Saravanapriah Nadarajan, Rajendiran Karthikraj, Kurunthachalam Kannan, Mónica P Colaiácovo
Published 2020-01-01

LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion.

by Yonatan B Tzur, Carlos Egydio de Carvalho, Saravanapriah Nadarajan, Ivo Van Bostelen, Yanjie Gu, Diana S Chu, Iain M Cheeseman, Monica P Colaiácovo
Published 2012-01-01

The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans.

by Qianyan Li, Takamune T Saito, Marina Martinez-Garcia, Alison J Deshong, Saravanapriah Nadarajan, Katherine S Lawrence, Paula M Checchi, Monica P Colaiacovo, JoAnne Engebrecht
Published 2018-11-01

Correction: Investigating the Role of RIO Protein Kinases in Caenorhabditis elegans.

by Tasha K Mendes, Stevan Novakovic, Greta Raymant, Sonja E Bertram, Reza Esmaillie, Saravanapriah Nadarajan, Bert Breugelmans, Andreas Hofmann, Robin B Gasser, Monica P Colaiácovo, Peter R Boag
Published 2016-01-01

Investigating the role of RIO protein kinases in Caenorhabditis elegans.

by Tasha K Mendes, Stevan Novakovic, Greta Raymant, Sonja E Bertram, Reza Esmaillie, Saravanapriah Nadarajan, Bert Breugelmans, Andreas Hofmann, Robin B Gasser, Monica P Colaiácovo, Peter R Boag
Published 2015-01-01

The MAP kinase pathway coordinates crossover designation with disassembly of synaptonemal complex proteins during meiosis

by Saravanapriah Nadarajan, Firaz Mohideen, Yonatan B Tzur, Nuria Ferrandiz, Oliver Crawley, Alex Montoya, Peter Faull, Ambrosius P Snijders, Pedro R Cutillas, Ashwini Jambhekar, Michael D Blower, Enrique Martinez-Perez, J Wade Harper, Monica P Colaiacovo
Published 2016-02-01

GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans.

by Marina Martinez-Garcia, Pedro Robles Naharro, Marnie W Skinner, Kerstin A Baran, Laura I Lascarez-Lagunas, Saravanapriah Nadarajan, Nara Shin, Carlos G Silva-García, Takamune T Saito, Sara Beese-Sims, Brianna N Diaz-Pacheco, Elizaveta Berson, Ana B Castañer, Sarai Pacheco, Enrique Martinez-Perez, Philip W Jordan, Monica P Colaiácovo
Published 2023-02-01

LAB-1 Targets PP1 and Restricts Aurora B Kinase upon Entrance into Meiosis to Promote Sister Chromatid Cohesion

by Egydio de Carvalho, Carlos, Van Bostelen, Ivo, Gu, Yanjie, Chu, Diana S., Cheeseman, Iain M., Tzur, Yonatan B, Nadarajan, Saravanapriah, Colaiacovo, Monica P.
Published 2013