Evaluating the robustness of connectivity methods to noise for in silico drug repurposing studies

by Nevin Tham, Sarah R. Langley
Published 2022-12-01

Differences in DBA/1J and DBA/2J reveal lipid QTL geness⃞

by Ioannis M. Stylianou, Sarah R. Langley, Kenneth Walsh, Yuan Chen, Céline Revenu, Beverly Paigen
Published 2008-11-01

Determining signalling nodes for apoptosis by a genetic high-throughput screen.

by Bevan Lin, Derek Huntley, Ghada Abuali, Sarah R Langley, George Sindelar, Enrico Petretto, Sarah Butcher, Stefan Grimm
Published 2011-01-01

Inhibition of miR-199a-3p in a murine hypertrophic cardiomyopathy (HCM) model attenuates fibrotic remodeling

by Irina Zalivina, Temo Barwari, Xiaoke Yin, Sarah R. Langley, Javier Barallobre-Barreiro, Hiroko Wakimoto, Anna Zampetaki, Manuel Mayr, Metin Avkiran, Seda Eminaga
Published 2023-12-01

Widespread dysregulation of mRNA splicing implicates RNA processing in the development and progression of Huntington's diseaseResearch in context

by Vincent Tano, Kagistia Hana Utami, Nur Amirah Binte Mohammad Yusof, Jocelyn Bégin, Willy Wei Li Tan, Mahmoud A. Pouladi, Sarah R. Langley
Published 2023-08-01

The habenula clock influences response to a stressor

by Adriana Basnakova, Ruey-Kuang Cheng, Joanne Shu Ming Chia, Giuseppe D'Agostino, Suryadi, Germaine Jia Hui Tan, Sarah R. Langley, Suresh Jesuthasan
Published 2021-11-01

New insights into the genetic control of gene expression using a Bayesian multi-tissue approach.

by Enrico Petretto, Leonardo Bottolo, Sarah R Langley, Matthias Heinig, Chris McDermott-Roe, Rizwan Sarwar, Michal Pravenec, Norbert Hübner, Timothy J Aitman, Stuart A Cook, Sylvia Richardson
Published 2010-04-01

Integrated systems‐genetic analyses reveal a network target for delaying glioma progression

by Liisi Laaniste, Prashant K. Srivastava, Julianna Stylianou, Nelofer Syed, Silvia Cases‐Cunillera, Kirill Shkura, Qingyu Zeng, Owen J. L. Rackham, Sarah R. Langley, Andree Delahaye-Duriez, Kevin O'Neill, Matthew Williams, Albert Becker, Federico Roncaroli, Enrico Petretto, Michael R. Johnson
Published 2019-09-01

Genetic analysis of the cardiac methylome at single nucleotide resolution in a model of human cardiovascular disease.

by Michelle D Johnson, Michael Mueller, Martyna Adamowicz-Brice, Melissa J Collins, Pascal Gellert, Klio Maratou, Prashant K Srivastava, Maxime Rotival, Shahena Butt, Laurence Game, Santosh S Atanur, Nicholas Silver, Penny J Norsworthy, Sarah R Langley, Enrico Petretto, Michal Pravenec, Timothy J Aitman
Published 2014-12-01

Testing for pharmacogenomic predictors of ppRNFL thinning in individuals exposed to vigabatrin

by Isabelle Boothman, Isabelle Boothman, Isabelle Boothman, Lisa M. Clayton, Lisa M. Clayton, Mark McCormack, Alexandra McKibben Driscoll, Remi Stevelink, Patrick Moloney, Roland Krause, Wolfram S. Kunz, Sarah Diehl, Terence J. O’Brien, Graeme J. Sills, Gerrit-Jan de Haan, Federico Zara, Federico Zara, Bobby P. Koeleman, Chantal Depondt, Anthony G. Marson, Hreinn Stefansson, Kari Stefansson, John Craig, Michael R. Johnson, Pasquale Striano, Pasquale Striano, Holger Lerche, Simon J. Furney, Norman Delanty, Consortium EpiPGX, Sanjay M. Sisodiya, Sanjay M. Sisodiya, Gianpiero L. Cavalleri, Gianpiero L. Cavalleri, Gianpiero L. Cavalleri, Joseph Willis, Mojgansadat Borghei, Simona Donatello, Martin J. Brodie, Pauls Auce, Andrea Jorgensen, Sarah R. Langley, Yvonne Weber, Christian Hengsbach, Martin Krenn, Fritz Zimprich, Ekaterina Pataraia, Karl Martin Klein, Hiltrud Muhle, Rikke S. Møller, Marina Nikanorova, Stefan Wolking, Ellen Campbell, Antonella Riva, Marcello Scala
Published 2023-09-01