Adverse Events Associated with Risperidone Use in Pediatric Patients: A Retrospective Biobank Study

by Kazeem A. Oshikoya, Robert Carroll, Ida Aka, Dan M. Roden, Sara L. Van Driest
Published 2019-03-01

Pediatric CYP2D6 metabolizer status and post‐tonsillectomy nausea and vomiting after ondansetron

by Katherine Black, B. Randall Brenn, Andrea Gaedigk, Jonathan P. Wanderer, Sara L. Van Driest
Published 2023-02-01

Characterizing Pharmacogenetic Testing Among Children’s Hospitals

by Jacob T. Brown, Laura B. Ramsey, Sara L. Van Driest, Ida Aka, Susan I. Colace
Published 2021-03-01

Population genetic testing and SERPINA1 sequencing identifies unidentified alpha-1 antitrypsin deficiency alleles and gene-environment interaction with hepatitis C infection

by Bryce A. Schuler, Lisa Bastarache, Janey Wang, Jing He, Sara L. Van Driest, Joshua C. Denny
Published 2023-01-01

Effect of SLCO1B1 Polymorphisms on High‐Dose Methotrexate Clearance in Children and Young Adults With Leukemia and Lymphoblastic Lymphoma

by Rachael R. Schulte, Leena Choi, Nipun Utreja, Sara L. Van Driest, C. Michael Stein, Richard H. Ho
Published 2021-01-01

Clinical Pharmacogenetics of Cytochrome P450-Associated Drugs in Children

by Ida Aka, Christiana J. Bernal, Robert Carroll, Angela Maxwell-Horn, Kazeem A. Oshikoya, Sara L. Van Driest
Published 2017-11-01

Influence of CYP2D6 genetic variation on adverse events with propafenone in the pediatric and young adult population

by Sudeep D. Sunthankar, Prince J. Kannankeril, Andrea Gaedigk, Andrew E. Radbill, Frank A. Fish, Sara L. Van Driest
Published 2022-07-01

Integrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associations.

by Jonathan D Mosley, Sara L Van Driest, Peter E Weeke, Jessica T Delaney, Quinn S Wells, Lisa Bastarache, Dan M Roden, Josh C Denny
Published 2014-01-01

We’re not all cut from the same cloth: TAILORing treatments for children with chronic conditions

by Rebecca N. Jerome, Jill M. Pulley, Terri L. Edwards, Alyssa B. Dickerson, Douglas Conway, Sara L. Van Driest, Gordon R. Bernard, Paul A. Harris
Published 2019-04-01

Medication history-wide association studies for pharmacovigilance of pregnant patients

by Anup P. Challa, Xinnan Niu, Etoi A. Garrison, Sara L. Van Driest, Lisa M. Bastarache, Ethan S. Lippmann, Robert R. Lavieri, Jeffery A. Goldstein, David M. Aronoff
Published 2022-09-01

Impact of Updating Pharmacogenetic Results: Lessons Learned from the PREDICT Program

by Michelle Liu, Sara L. Van Driest, Cindy L. Vnencak-Jones, Leigh Ann G. Saucier, Bartholomew P. Roland, Cheryl L. Gatto, Shari L. Just, Asli O. Weitkamp, Josh F. Peterson
Published 2021-10-01

Phenotype-Driven Plasma Biobanking Strategies and Methods

by Erica A. Bowton, Sarah P. Collier, Xiaoming Wang, Cara B. Sutcliffe, Sara L. Van Driest, Lindsay J. Couch, Miguel Herrera, Rebecca N. Jerome, Robbert J. C. Slebos, William E. Alborn, Daniel C. Liebler, Candace D. McNaughton, Ray L. Mernaugh, Quinn S. Wells, Nancy J. Brown, Dan M. Roden, Jill M. Pulley
Published 2015-05-01

Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data.

by Jonathan D Mosley, Sara L Van Driest, Emma K Larkin, Peter E Weeke, John S Witte, Quinn S Wells, Jason H Karnes, Yan Guo, Lisa Bastarache, Lana M Olson, Catherine A McCarty, Jennifer A Pacheco, Gail P Jarvik, David S Carrell, Eric B Larson, David R Crosslin, Iftikhar J Kullo, Gerard Tromp, Helena Kuivaniemi, David J Carey, Marylyn D Ritchie, Josh C Denny, Dan M Roden
Published 2013-01-01

Clinical associations with a polygenic predisposition to benign lower white blood cell counts

by Jonathan D. Mosley, John P. Shelley, Alyson L. Dickson, Jacy Zanussi, Laura L. Daniel, Neil S. Zheng, Lisa Bastarache, Wei-Qi Wei, Mingjian Shi, Gail P. Jarvik, Elisabeth A. Rosenthal, Atlas Khan, Alborz Sherafati, Iftikhar J. Kullo, Theresa L. Walunas, Joseph Glessner, Hakon Hakonarson, Nancy J. Cox, Dan M. Roden, Stephan G. Frangakis, Brett Vanderwerff, C. Michael Stein, Sara L. Van Driest, Scott C. Borinstein, Xiao-Ou Shu, Matthew Zawistowski, Cecilia P. Chung, Vivian K. Kawai
Published 2024-04-01

Genome-Wide Association Study of Serum Creatinine Levels during Vancomycin Therapy.

by Sara L Van Driest, Tracy L McGregor, Digna R Velez Edwards, Ben R Saville, Terrie E Kitchner, Scott J Hebbring, Murray Brilliant, Hayan Jouni, Iftikhar J Kullo, C Buddy Creech, Prince J Kannankeril, Susan I Vear, Kyle B Brothers, Erica A Bowton, Christian M Shaffer, Neelam Patel, Jessica T Delaney, Yuki Bradford, Sarah Wilson, Lana M Olson, Dana C Crawford, Amy L Potts, Richard H Ho, Dan M Roden, Josh C Denny
Published 2015-01-01

Best–worst scaling methodology to evaluate constructs of the Consolidated Framework for Implementation Research: application to the implementation of pharmacogenetic testing for an...

by Ramzi G. Salloum, Jeffrey R. Bishop, Amanda L. Elchynski, D. Max Smith, Elizabeth Rowe, Kathryn V. Blake, Nita A. Limdi, Christina L. Aquilante, Jill Bates, Amber L. Beitelshees, Amber Cipriani, Benjamin Q. Duong, Philip E. Empey, Christine M. Formea, J. Kevin Hicks, Pawel Mroz, David Oslin, Amy L. Pasternak, Natasha Petry, Laura B. Ramsey, Allyson Schlichte, Sandra M. Swain, Kristen M. Ward, Kristin Wiisanen, Todd C. Skaar, Sara L. Van Driest, Larisa H. Cavallari, Sony Tuteja
Published 2022-05-01

Multisite evaluation of institutional processes and implementation determinants for pharmacogenetic testing to guide antidepressant therapy

by Sony Tuteja, Ramzi G. Salloum, Amanda L. Elchynski, D. Max Smith, Elizabeth Rowe, Kathryn V. Blake, Nita A. Limdi, Christina L. Aquilante, Jill Bates, Amber L. Beitelshees, Amber Cipriani, Benjamin Q. Duong, Philip E. Empey, Christine M. Formea, J. Kevin Hicks, Pawel Mroz, David Oslin, Amy L. Pasternak, Natasha Petry, Laura B. Ramsey, Allyson Schlichte, Sandra M. Swain, Kristen M. Ward, Kristin Wiisanen, Todd C. Skaar, Sara L. Van Driest, Larisa H. Cavallari, Jeffrey R. Bishop, for the IGNITE Pharmacogenetics Working Group
Published 2022-02-01

Rationale and design for a pragmatic randomized trial to assess gene‐based prescribing for SSRIs in the treatment of depression

by Lindsay J. Hines, Russell A. Wilke, Rachel Myers, Carol A. Mathews, Michelle Liu, Jordan F. Baye, Natasha Petry, Emily J. Cicali, Benjamin Q. Duong, Erica Elwood, Leslie Hulvershorn, Khoa Nguyen, Michelle Ramos, Azita Sadeghpour, R. Ryanne Wu, Lloyda Williamson, Kristin Wiisanen, Deepak Voora, Rajbir Singh, Kathryn V. Blake, James W. Murrough, Simona Volpi, Geoffrey S. Ginsburg, Carol R. Horowitz, Lori Orlando, Hrishikesh Chakraborty, Paul Dexter, Julie A. Johnson, Todd C. Skaar, Larisa H. Cavallari, Sara L. Van Driest, Josh F. Peterson, the IGNITE Pragmatic Trials Network
Published 2024-06-01

A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers

by Jonathan D. Mosley, QiPing Feng, Quinn S. Wells, Sara L. Van Driest, Christian M. Shaffer, Todd L. Edwards, Lisa Bastarache, Wei-Qi Wei, Lea K. Davis, Catherine A. McCarty, Will Thompson, Christopher G. Chute, Gail P. Jarvik, Adam S. Gordon, Melody R. Palmer, David R. Crosslin, Eric B. Larson, David S. Carrell, Iftikhar J. Kullo, Jennifer A. Pacheco, Peggy L. Peissig, Murray H. Brilliant, James G. Linneman, Bahram Namjou, Marc S. Williams, Marylyn D. Ritchie, Kenneth M. Borthwick, Shefali S. Verma, Jason H. Karnes, Scott T. Weiss, Thomas J. Wang, C. Michael Stein, Josh C. Denny, Dan M. Roden
Published 2018-08-01

Returning Results in the Genomic Era: Initial Experiences of the eMERGE Network

by Georgia L. Wiesner, Alanna Kulchak Rahm, Paul Appelbaum, Sharon Aufox, Sarah T. Bland, Carrie L. Blout, Kurt D. Christensen, Wendy K. Chung, Ellen Wright Clayton, Robert C. Green, Margaret H. Harr, Nora Henrikson, Christin Hoell, Ingrid A. Holm, Gail P. Jarvik, Iftikhar J. Kullo, Philip E. Lammers, Eric B. Larson, Noralane M. Lindor, Maddalena Marasa, Melanie F. Myers, Josh F. Peterson, Cynthia A. Prows, James D. Ralston, Hila Milo Rasouly, Richard R. Sharp, Maureen E. Smith, Sara L. Van Driest, Janet L. Williams, Marc S. Williams, Julia Wynn, Kathleen A. Leppig
Published 2020-04-01