Frequency and impact of slow flow / no flow in primary percutaneous coronary intervention

by Ghazanfer Ali Shah, Tooba malik, Sadaf Farooqi, Salman Ahmed, Khadijah Abid
Published 2021-09-01

A novel mutation in the leptin gene (W121X) in an Egyptian family

by Inas Mazen, Khalda Amr, Sally Tantawy, I. Sadaf Farooqi, Mona El Gammal
Published 2014-01-01

MicroRNA-7 regulates melanocortin circuits involved in mammalian energy homeostasis

by Mary P. LaPierre, Katherine Lawler, Svenja Godbersen, I. Sadaf Farooqi, Markus Stoffel
Published 2022-09-01

Genetic variance in the spinocerebellar ataxia type 2 (ATXN2) gene in children with severe early onset obesity.

by Karla P Figueroa, Sadaf Farooqi, Kristopher Harrup, Johnathan Frank, Stephen O'Rahilly, Stefan M Pulst
Published 2009-12-01

Visualization of sympathetic neural innervation in human white adipose tissue

by Aliki Perdikari, Tessa Cacciottolo, Elana Henning, Edson Mendes de Oliveira, Julia M. Keogh, I. Sadaf Farooqi
Published 2022-03-01

Oxytocin administration suppresses hypothalamic activation in response to visual food cues

by Agatha A. van der Klaauw, Hisham Ziauddeen, Julia M. Keogh, Elana Henning, Sekesai Dachi, Paul C. Fletcher, I. Sadaf Farooqi
Published 2017-06-01

Long-term stabilization effects of leptin on brain functions in a leptin-deficient patient.

by Sabine Frank, Martin Heni, Anja Moss, Julia von Schnurbein, Sadaf Farooqi, Hans-Ulrich Häring, Andreas Fritsche, Hubert Preissl, Martin Wabitsch
Published 2013-01-01

Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila.

by Neha Agrawal, Katherine Lawler, Catherine M Davidson, Julia M Keogh, Robert Legg, INTERVAL, Inês Barroso, I Sadaf Farooqi, Andrea H Brand
Published 2021-11-01

Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila

by Neha Agrawal, Katherine Lawler, Catherine M. Davidson, Julia M. Keogh, Robert Legg, INTERVAL, Inês Barroso, I. Sadaf Farooqi, Andrea H. Brand
Published 2021-11-01

ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls.

by Audrey E Hendricks, Stephen C Billups, Hamish N C Pike, I Sadaf Farooqi, Eleftheria Zeggini, Stephanie A Santorico, Inês Barroso, Josée Dupuis
Published 2018-10-01

Neural correlates of fat preference in frontotemporal dementia: translating insights from the obesity literature

by Rebekah M. Ahmed, Nga Yan Tse, Yu Chen, Elana Henning, John R. Hodges, Matthew C. Kiernan, Muireann Irish, I. Sadaf Farooqi, Olivier Piguet
Published 2021-06-01

Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels

by Sumit Bhattacharyya, Jian'an Luan, Benjamin Challis, Julia Keogh, Carl Montague, John Brennand, John Morten, Sarah Lowenbeim, Suzanne Jenkins, I. Sadaf Farooqi, Nicholas J. Wareham, Stephen O'Rahilly
Published 2006-04-01

Divergent effects of central melanocortin signalling on fat and sucrose preference in humans

by Agatha A. van der Klaauw, Julia M. Keogh, Elana Henning, Cheryl Stephenson, Sarah Kelway, Victoria M. Trowse, Naresh Subramanian, Stephen O’Rahilly, Paul C. Fletcher, I. Sadaf Farooqi
Published 2016-10-01

Neural networks associated with body composition in frontotemporal dementia

by Rebekah M. Ahmed, Ramon Landin‐Romero, Cheng T. Liang, Julia M. Keogh, Elana Henning, Cherie Strikwerda‐Brown, Emma M. Devenney, John R. Hodges, Matthew C. Kiernan, I. Sadaf Farooqi, Olivier Piguet
Published 2019-09-01

A Transcriptomic Signature of the Hypothalamic Response to Fasting and BDNF Deficiency in Prader-Willi Syndrome

by Elena G. Bochukova, Katherine Lawler, Sophie Croizier, Julia M. Keogh, Nisha Patel, Garth Strohbehn, Kitty K. Lo, Jack Humphrey, Anita Hokken-Koelega, Layla Damen, Stephany Donze, Sebastien G. Bouret, Vincent Plagnol, I. Sadaf Farooqi
Published 2018-03-01

Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis

by Peter Kirwan, Richard G. Kay, Bas Brouwers, Vicente Herranz-Pérez, Magdalena Jura, Pierre Larraufie, Julie Jerber, Jason Pembroke, Theresa Bartels, Anne White, Fiona M. Gribble, Frank Reimann, I. Sadaf Farooqi, Stephen O'Rahilly, Florian T. Merkle
Published 2018-11-01

Genetic architecture of human thinness compared to severe obesity.

by Fernando Riveros-McKay, Vanisha Mistry, Rebecca Bounds, Audrey Hendricks, Julia M Keogh, Hannah Thomas, Elana Henning, Laura J Corbin, Understanding Society Scientific Group, Stephen O'Rahilly, Eleftheria Zeggini, Eleanor Wheeler, Inês Barroso, I Sadaf Farooqi
Published 2019-01-01

Trappc9 deficiency causes parent-of-origin dependent microcephaly and obesity.

by Zhengzheng S Liang, Irene Cimino, Binnaz Yalcin, Narayanan Raghupathy, Valerie E Vancollie, Ximena Ibarra-Soria, Helen V Firth, Debra Rimmington, I Sadaf Farooqi, Christopher J Lelliott, Steven C Munger, Stephen O'Rahilly, Anne C Ferguson-Smith, Anthony P Coll, Darren W Logan
Published 2020-09-01

Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation

by Bas Brouwers, Edson Mendes de Oliveira, Maria Marti-Solano, Fabiola B.F. Monteiro, Suli-Anne Laurin, Julia M. Keogh, Elana Henning, Rebecca Bounds, Carole A. Daly, Shane Houston, Vikram Ayinampudi, Natalia Wasiluk, David Clarke, Bianca Plouffe, Michel Bouvier, M. Madan Babu, I. Sadaf Farooqi, Jacek Mokrosiński
Published 2021-03-01

A rare human variant that disrupts GPR10 signalling causes weight gain in mice

by Fleur Talbot, Claire H. Feetham, Jacek Mokrosiński, Katherine Lawler, Julia M. Keogh, Elana Henning, Edson Mendes de Oliveira, Vikram Ayinampudi, Sadia Saeed, Amélie Bonnefond, Mohammed Arslan, Giles S. H. Yeo, Philippe Froguel, David A. Bechtold, Antony Adamson, Neil Humphreys, Inês Barroso, Simon M. Luckman, I. Sadaf Farooqi
Published 2023-03-01