CFTR Rescue in Intestinal Organoids with GLPG/ABBV-2737, ABBV/GLPG-2222 and ABBV/GLPG-2451 Triple Therapy

by Eyleen de Poel, Eyleen de Poel, Sacha Spelier, Sacha Spelier, Ricardo Korporaal, Ka Wai Lai, Sylvia F. Boj, Katja Conrath, Cornelis K. van der Ent, Jeffrey M. Beekman, Jeffrey M. Beekman
Published 2021-09-01

Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy

by Else Driehuis, Sacha Spelier, Irati Beltrán Hernández, Remco de Bree, Stefan M. Willems, Hans Clevers, Sabrina Oliveira
Published 2019-11-01

High-throughput functional assay in cystic fibrosis patient-derived organoids allows drug repurposing

by Sacha Spelier, Eyleen de Poel, Georgia N. Ithakisiou, Sylvia W.F. Suen, Marne C. Hagemeijer, Danya Muilwijk, Annelotte M. Vonk, Jesse E. Brunsveld, Evelien Kruisselbrink, Cornelis K. van der Ent, Jeffrey M. Beekman
Published 2023-01-01