A Pathophysiological Intersection of Diabetes and Alzheimer’s Disease

by Maša Čater, Sabine M. Hölter
Published 2022-09-01

cGMP-dependent protein kinase I, the circadian clock, sleep and learning

by Robert Feil, Sabine M. Hölter, Karin Weindl, Wolfgang Wurst, Sonia Langmesser, Andrea Gerling, Susanne Feil, Urs Albrecht
Published 2009-07-01

RNase H2 Loss in Murine Astrocytes Results in Cellular Defects Reminiscent of Nucleic Acid-Mediated Autoinflammation

by Kareen Bartsch, Markus Damme, Tommy Regen, Lore Becker, Lillian Garrett, Lillian Garrett, Sabine M Hölter, Sabine M Hölter, Katharina Knittler, Christopher Borowski, Ari Waisman, Markus Glatzel, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabe de Angelis, Martin Hrabe de Angelis, Martin Hrabe de Angelis, Björn Rabe
Published 2018-03-01

FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum.

by Florian Meier, Florian Giesert, Sabit Delic, Theresa Faus-Kessler, Friederike Matheus, Antonio Simeone, Sabine M Hölter, Ralf Kühn, Daniela M Vogt Weisenhorn, Wolfgang Wurst, Nilima Prakash
Published 2014-01-01

Claudin-12 is not required for blood–brain barrier tight junction function

by Mariana Castro Dias, Caroline Coisne, Pascale Baden, Gaby Enzmann, Lillian Garrett, Lore Becker, Sabine M. Hölter, German Mouse Clinic Consortium, Martin Hrabě de Angelis, Urban Deutsch, Britta Engelhardt
Published 2019-09-01

Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice

by Ulrich Schweizer, Eva K. Wirth, Thomas Klopstock, Sabine M. Hölter, Lore Becker, Jackob Moskovitz, Tilman Grune, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabe de Angelis, Josef Köhrle, Lutz Schomburg
Published 2022-11-01

Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans

by Peter Baumann, Sonja C. Schriever, Stephanie Kullmann, Annemarie Zimprich, Andreas Peter, Valerie Gailus‐Durner, Helmut Fuchs, Martin Hrabe de Angelis, Wolfgang Wurst, Matthias H. Tschöp, Martin Heni, Sabine M. Hölter, Paul T. Pfluger
Published 2021-01-01

MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adults.

by Benedikt Wefers, Christiane Hitz, Sabine M Hölter, Dietrich Trümbach, Jens Hansen, Peter Weber, Benno Pütz, Jan M Deussing, Martin Hrabé de Angelis, Till Roenneberg, Fang Zheng, Christian Alzheimer, Alcino Silva, Wolfgang Wurst, Ralf Kühn
Published 2012-01-01

Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments.

by Kimberly B Zumbrennen-Bullough, Lore Becker, Lillian Garrett, Sabine M Hölter, Julia Calzada-Wack, Ilona Mossbrugger, Leticia Quintanilla-Fend, Ildiko Racz, Birgit Rathkolb, Thomas Klopstock, Wolfgang Wurst, Andreas Zimmer, Eckhard Wolf, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Steven J Romney, Elizabeth A Leibold
Published 2014-01-01

Recommendations for robust and reproducible preclinical research in personalised medicine

by Vibeke Fosse, Emanuela Oldoni, Florence Bietrix, Alfredo Budillon, Evangelos P. Daskalopoulos, Maddalena Fratelli, Björn Gerlach, Peter M. A. Groenen, Sabine M. Hölter, Julia M. L. Menon, Ali Mobasheri, Nikki Osborne, Merel Ritskes-Hoitinga, Bettina Ryll, Elmar Schmitt, Anton Ussi, Antonio L. Andreu, Emmet McCormack, on behalf of The PERMIT group
Published 2023-01-01

Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons

by Jessica Giehrl‐Schwab, Florian Giesert, Benedict Rauser, Chu Lan Lao, Sina Hembach, Sandrine Lefort, Ignacio L Ibarra, Christina Koupourtidou, Malte Daniel Luecken, Dong‐Jiunn Jeffery Truong, Judith Fischer‐Sternjak, Giacomo Masserdotti, Nilima Prakash, Jovica Ninkovic, Sabine M Hölter, Daniela M Vogt Weisenhorn, Fabian J Theis, Magdalena Götz, Wolfgang Wurst
Published 2022-05-01

Meis1: effects on motor phenotypes and the sensorimotor system in mice

by Aaro V. Salminen, Lillian Garrett, Barbara Schormair, Jan Rozman, Florian Giesert, Kristina M. Niedermeier, Lore Becker, Birgit Rathkolb, Ildikó Rácz, German Mouse Clinic Consortium, Martin Klingenspor, Thomas Klopstock, Eckhard Wolf, Andreas Zimmer, Valérie Gailus-Durner, Miguel Torres, Helmut Fuchs, Martin Hrabě de Angelis, Wolfgang Wurst, Sabine M. Hölter, Juliane Winkelmann
Published 2017-08-01

Conditional reduction of adult born doublecortin-positive neurons reversibly impairs selective behaviours

by Lillian eGarrett, Jingzhong eZhang, Annemarie eZimprich, Kristina M Niedermeier, Kristina M Niedermeier, Helmut eFuchs, Valerie eGailus-Durner, Martin eHrabe de Angelis, Martin eHrabe de Angelis, Daniela eVogt-Weisenhorn, Wolfgang eWurst, Wolfgang eWurst, Wolfgang eWurst, Wolfgang eWurst, Sabine M Hölter
Published 2015-11-01

Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1 I27N mutant mice

by Sudhir Kumar, Birgit Rathkolb, Sibylle Sabrautzki, Stefan Krebs, Elisabeth Kemter, Lore Becker, Johannes Beckers, Raffi Bekeredjian, Robert Brommage, Julia Calzada-Wack, Lillian Garrett, Sabine M. Hölter, Marion Horsch, Martin Klingenspor, Thomas Klopstock, Kristin Moreth, Frauke Neff, Jan Rozman, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabe de Angelis, Eckhard Wolf, Bernhard Aigner
Published 2017-08-01

A robust and reliable non-invasive test for stress responsivity in mice

by Annemarie eZimprich, Lillian eGarrett, Jan M Deussing, Jan M Deussing, Carsten T. Wotjak, Helmut eFuchs, Valerie eGailus-Durner, Martin eHrabe de Angelis, Martin eHrabe de Angelis, Martin eHrabe de Angelis, Wolfgang eWurst, Wolfgang eWurst, Wolfgang eWurst, Wolfgang eWurst, Wolfgang eWurst, Sabine M Hölter
Published 2014-04-01

Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans.

by Pawel K Olszewski, Jan Rozman, Josefin A Jacobsson, Birgit Rathkolb, Siv Strömberg, Wolfgang Hans, Anica Klockars, Johan Alsiö, Ulf Risérus, Lore Becker, Sabine M Hölter, Ralf Elvert, Nicole Ehrhardt, Valérie Gailus-Durner, Helmut Fuchs, Robert Fredriksson, Eckhard Wolf, Thomas Klopstock, Wolfgang Wurst, Allen S Levine, Claude Marcus, Martin Hrabě de Angelis, Martin Klingenspor, Helgi B Schiöth, Manfred W Kilimann
Published 2012-01-01

Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk

by Lillian Garrett, Patricia Da Silva-Buttkus, Birgit Rathkolb, Raffaele Gerlini, Lore Becker, Adrian Sanz-Moreno, Claudia Seisenberger, Annemarie Zimprich, Antonio Aguilar-Pimentel, Oana V. Amarie, Yi-Li Cho, Markus Kraiger, Nadine Spielmann, Julia Calzada-Wack, Susan Marschall, Dirk Busch, Carsten Schmitt-Weber, Eckhard Wolf, Wolfgang Wurst, Helmut Fuchs, Valerie Gailus-Durner, Sabine M. Hölter, Martin Hrabě de Angelis
Published 2022-03-01

Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice.

by Sudhir Kumar, Birgit Rathkolb, Elisabeth Kemter, Sibylle Sabrautzki, Dian Michel, Thure Adler, Lore Becker, Johannes Beckers, Dirk H Busch, Lillian Garrett, Wolfgang Hans, Sabine M Hölter, Marion Horsch, Martin Klingenspor, Thomas Klopstock, Ildikó Rácz, Jan Rozman, Ingrid Liliana Vargas Panesso, Alexandra Vernaleken, Andreas Zimmer, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabě de Angelis, Eckhard Wolf, Bernhard Aigner
Published 2016-01-01

MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.

by Lore Becker, Eva Kling, Evelyn Schiller, Ramona Zeh, Anja Schrewe, Sabine M Hölter, Ilona Mossbrugger, Julia Calzada-Wack, Valentina Strecker, Ilka Wittig, Iulia Dumitru, Tina Wenz, Andreas Bender, Michaela Aichler, Dirk Janik, Frauke Neff, Axel Walch, Leticia Quintanilla-Fend, Thomas Floss, Raffi Bekeredjian, Valérie Gailus-Durner, Helmut Fuchs, Wolfgang Wurst, Thomas Meitinger, Holger Prokisch, Martin Hrabě de Angelis, Thomas Klopstock
Published 2014-01-01

Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.

by Viola André, Christine Gau, Angelika Scheideler, Juan A Aguilar-Pimentel, Oana V Amarie, Lore Becker, Lillian Garrett, Wolfgang Hans, Sabine M Hölter, Dirk Janik, Kristin Moreth, Frauke Neff, Manuela Östereicher, Ildiko Racz, Birgit Rathkolb, Jan Rozman, Raffi Bekeredjian, Jochen Graw, Martin Klingenspor, Thomas Klopstock, Markus Ollert, Carsten Schmidt-Weber, Eckhard Wolf, Wolfgang Wurst, Valérie Gailus-Durner, Markus Brielmeier, Helmut Fuchs, Martin Hrabé de Angelis
Published 2018-04-01