The immunological mechanisms that control pneumococcal carriage.

by Simon P Jochems, Jeffrey N Weiser, Richard Malley, Daniela M Ferreira
Published 2017-12-01

Insights Into the Effects of Mucosal Epithelial and Innate Immune Dysfunction in Older People on Host Interactions With Streptococcus pneumoniae

by Caroline M. Weight, Simon P. Jochems, Hugh Adler, Hugh Adler, Daniela M. Ferreira, Jeremy S. Brown, Robert S. Heyderman
Published 2021-05-01

Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface

by Caroline M. Weight, Cristina Venturini, Sherin Pojar, Simon P. Jochems, Jesús Reiné, Elissavet Nikolaou, Carla Solórzano, Mahdad Noursadeghi, Jeremy S. Brown, Daniela M. Ferreira, Robert S. Heyderman
Published 2019-07-01

Biomarkers of the ageing immune system and their association with frailty – A systematic review

by E. Tran Van Hoi, N.A. De Glas, J.E.A. Portielje, D. Van Heemst, F. Van Den Bos, S.P. Jochems, S.P. Mooijaart
Published 2023-06-01

Intact type I Interferon production and IRF7 function in sooty mangabeys.

by Steven E Bosinger, Zachary P Johnson, Kathryn A Folkner, Nirav Patel, Tayebeh Hashempour, Simon P Jochems, Perla M Del Rio Estrada, Mirko Paiardini, Rongtuan Lin, Thomas H Vanderford, John Hiscott, Guido Silvestri
Published 2013-01-01

Influence of sex, season and environmental air quality on experimental human pneumococcal carriage acquisition: a retrospective cohort analysis

by Katerina S. Cheliotis, Christopher P. Jewell, Carla Solórzano, Britta Urban, Andrea M. Collins, Elena Mitsi, Sherin Pojar, Elissavet Nikolaou, Esther L. German, Jesús Reiné, Stephen B. Gordon, Simon P. Jochems, Jamie Rylance, Daniela M. Ferreira
Published 2022-04-01

Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection.

by Béatrice Jacquelin, Gaël Petitjean, Désirée Kunkel, Anne-Sophie Liovat, Simon P Jochems, Kenneth A Rogers, Mickaël J Ploquin, Yoann Madec, Françoise Barré-Sinoussi, Nathalie Dereuddre-Bosquet, Pierre Lebon, Roger Le Grand, François Villinger, Michaela Müller-Trutwin
Published 2014-07-01

Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine

by Wouter A. A. de Steenhuijsen Piters, Simon P. Jochems, Elena Mitsi, Jamie Rylance, Sherin Pojar, Elissavet Nikolaou, Esther L. German, Mark Holloway, Beatriz F. Carniel, Mei Ling J. N. Chu, Kayleigh Arp, Elisabeth A. M. Sanders, Daniela M. Ferreira, Debby Bogaert
Published 2019-07-01

Novel Analysis of Immune Cells from Nasal Microbiopsy Demonstrates Reliable, Reproducible Data for Immune Populations, and Superior Cytokine Detection Compared to Nasal Wash.

by Simon P Jochems, Katherine Piddock, Jamie Rylance, Hugh Adler, Beatriz F Carniel, Andrea Collins, Jenna F Gritzfeld, Carole Hancock, Helen Hill, Jesus Reiné, Alexandra Seddon, Carla Solórzano, Syba Sunny, Ashleigh Trimble, Angela D Wright, Seher Zaidi, Stephen B Gordon, Daniela M Ferreira
Published 2017-01-01

Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine

by Beatriz F. Carniel, Fernando Marcon, Jamie Rylance, Esther L. German, Seher Zaidi, Jesus Reiné, Edessa Negera, Elissavet Nikolaou, Sherin Pojar, Carla Solórzano, Andrea M. Collins, Victoria Connor, Debbie Bogaert, Stephen B. Gordon, Helder I. Nakaya, Daniela M. Ferreira, Simon P. Jochems, Elena Mitsi
Published 2021-02-01

Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults

by Elissavet Nikolaou, Simon P. Jochems, Elena Mitsi, Sherin Pojar, Annie Blizard, Jesus Reiné, Carla Solórzano, Edessa Negera, Beatriz Carniel, Alessandra Soares-Schanoski, Victoria Connor, Hugh Adler, Seher R. Zaidi, Caz Hales, Helen Hill, Angie Hyder-Wright, Stephen B. Gordon, Jamie Rylance, Daniela M. Ferreira
Published 2021-02-01

Combinatorial multimer staining and spectral flow cytometry facilitate quantification and characterization of polysaccharide-specific B cell immunity

by Dennis Hoving, Alexandre H. C. Marques, Wesley Huisman, Beckley A. Nosoh, Alicia C. de Kroon, Oscar R. J. van Hengel, Bing-Ru Wu, Rosanne A. M. Steenbergen, Pauline M. van Helden, Britta C. Urban, Nisha Dhar, Daniela M. Ferreira, Gaurav Kwatra, Cornelis H. Hokke, Simon P. Jochems
Published 2023-10-01

Characterization of T cell responses to co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in healthy adults in Gabon.

by Yoanne D Mouwenda, Madeleine E Betouke Ongwe, Friederike Sonnet, Koen A Stam, Lucja A Labuda, Sophie De Vries, Martin P Grobusch, Frejus J Zinsou, Yabo J Honkpehedji, Jean-Claude Dejon Agobe, David J Diemert, Remko van Leeuwen, Maria E Bottazzi, Peter J Hotez, Peter G Kremsner, Jeffrey M Bethony, Simon P Jochems, Ayola A Adegnika, Marguerite Massinga Loembe, Maria Yazdanbakhsh
Published 2021-10-01

Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization

by Simon P. Jochems, Karin de Ruiter, Carla Solórzano, Astrid Voskamp, Elena Mitsi, Elissavet Nikolaou, Beatriz F. Carniel, Sherin Pojar, Esther L. German, Jesús Reiné, Alessandra Soares-Schanoski, Helen Hill, Rachel Robinson, Angela D. Hyder-Wright, Caroline M. Weight, Pascal F. Durrenberger, Robert S. Heyderman, Stephen B. Gordon, Hermelijn H. Smits, Britta C. Urban, Jamie Rylance, Andrea M. Collins, Mark D. Wilkie, Lepa Lazarova, Samuel C. Leong, Maria Yazdanbakhsh, Daniela M. Ferreira
Published 2022-06-01

Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset.

by Mickaël J Ploquin, Yoann Madec, Armanda Casrouge, Nicolas Huot, Caroline Passaes, Camille Lécuroux, Asma Essat, Faroudy Boufassa, Béatrice Jacquelin, Simon P Jochems, Gaël Petitjean, Mathieu Angin, Kathleen Gärtner, Thalía Garcia-Tellez, Nicolas Noël, Thijs Booiman, Brigitte D Boeser-Nunnink, Pierre Roques, Asier Saez-Cirion, Bruno Vaslin, Nathalie Dereudre-Bosquet, Françoise Barré-Sinoussi, Mathilde Ghislain, Christine Rouzioux, Olivier Lambotte, Matthew L Albert, Cécile Goujard, Neeltje Kootstra, Laurence Meyer, Michaela C Müller-Trutwin
Published 2016-08-01

Immunogenicity and reactogenicity of intradermal mRNA-1273 SARS-CoV-2 vaccination: a non-inferiority, randomized-controlled trial

by Manon L. M. Prins, Geert V. T. Roozen, Cilia. R. Pothast, Wesley Huisman, Rob van Binnendijk, Gerco den Hartog, Vincent P. Kuiper, Corine Prins, Jacqueline J. Janse, Olivia. A. C. Lamers, Jan Pieter R. Koopman, Annelieke C. Kruithof, Ingrid M. C. Kamerling, Romy C. Dijkland, Alicia. C. de Kroon, Shohreh Azimi, Mariet C. W. Feltkamp, Marjan Kuijer, Simon P. Jochems, Mirjam H. M. Heemskerk, Frits R. Rosendaal, Meta Roestenberg, Leo G. Visser, Anna H. E. Roukens
Published 2024-01-01

Safety and infectivity of female cercariae in Schistosoma-naïve, healthy participants: a controlled human Schistosoma mansoni infection studyResearch in context

by Jan Pieter R. Koopman, Emma L. Houlder, Jacqueline J. Janse, Miriam Casacuberta-Partal, Olivia A.C. Lamers, Jeroen C. Sijtsma, Claudia de Dood, Stan T. Hilt, Arifa Ozir-Fazalalikhan, Vincent P. Kuiper, Geert V.T. Roozen, Laura M. de Bes-Roeleveld, Yvonne C.M. Kruize, Linda J. Wammes, Hermelijn H. Smits, Lisette van Lieshout, Govert J. van Dam, Inge M. van Amerongen-Westra, Pauline Meij, Paul L.A.M. Corstjens, Simon P. Jochems, Angela van Diepen, Maria Yazdanbakhsh, Cornelis H. Hokke, Meta Roestenberg
Published 2023-11-01

Host biomarker-based quantitative rapid tests for detection and treatment monitoring of tuberculosis and COVID-19

by Louise Pierneef, Anouk van Hooij, Danielle de Jong, Elisa M. Tjon Kon Fat, Krista E. van Meijgaarden, Elisa Petruccioli, Valentina Vanini, Anna H.E. Roukens, Delia Goletti, Paul L.A.M. Corstjens, Simone A. Joosten, Annemieke Geluk, M.S. Arbous, B.M. van den Berg, S. Cannegieter, C.M. Cobbaert, A. van der Does, J.J.M. van Dongen, J. Eikenboom, M.C.M. Feltkamp, A. Geluk, J.J. Goeman, M. Giera, T. Hankemeier, M.H.M. Heemskerk, P.S. Hiemstra, C.H. Hokke, J.J. Janse, S.P. Jochems, S.A. Joosten, M. Kikkert, L. Lamont, J. Manniën, T.H.M. Ottenhoff, M.R. del Prado, N. Queralt Rosinach, M. Roestenberg, M. Roos, A.H.E. Roukens, H.H. Smits, E.J. Snijder, F.J.T. Staal, L.A. Trouw, R. Tsonaka, A. Verhoeven, L.G. Visser, J.J.C. de Vries, D.J. van Westerloo, J. Wigbers, H.J. van der Wijk, R.C. van Wissen, M. Wuhrer, M. Yazdanbakhsh, M. Zlei
Published 2023-01-01