Current State and Issues of Regenerative Medicine for Rheumatic Diseases

by Ryusuke Yoshimi, Hideaki Nakajima
Published 2022-01-01

Immature functional development of lumbar locomotor networks in adult Irf8−/− mice

by Itaru Yazawa, Itaru Yazawa, Yuko Yoshida, Ryusuke Yoshimi, Ryusuke Yoshimi, Keiko Ozato
Published 2024-01-01

Autoantigen TRIM21/Ro52 as a Possible Target for Treatment of Systemic Lupus Erythematosus

by Ryusuke Yoshimi, Yoshiaki Ishigatsubo, Keiko Ozato
Published 2012-01-01

The PRY/SPRY domain of pyrin/TRIM20 interacts with β2-microglobulin to promote inflammasome formation

by Sei Samukawa, Ryusuke Yoshimi, Yohei Kirino, Hideaki Nakajima
Published 2021-12-01

Clinical and Pathological Roles of Ro/SSA Autoantibody System

by Ryusuke Yoshimi, Atsuhisa Ueda, Keiko Ozato, Yoshiaki Ishigatsubo
Published 2012-01-01

The Roles of Monocytes and Macrophages in Behçet’s Disease With Focus on M1 and M2 Polarization

by Lisa Hirahara, Kaoru Takase-Minegishi, Yohei Kirino, Yuki Iizuka-Iribe, Yutaro Soejima, Ryusuke Yoshimi, Hideaki Nakajima
Published 2022-03-01

Risk of Macrophage Activation Syndrome in Patients with Adult-Onset Still’s Disease Treated with IL-1 and IL-6 Inhibitors: A Meta-analysis and Single-Center Experience

by Soichiro Adachi, Kaoru Takase-Minegishi, Ayaka Maeda, Hideto Nagai, Nobuyuki Horita, Ryusuke Yoshimi, Yohei Kirino, Hideaki Nakajima
Published 2023-10-01

GWAS-identified CCR1 and IL10 loci contribute to M1 macrophage-predominant inflammation in Behçet’s disease

by Hiroto Nakano, Yohei Kirino, Mitsuhiro Takeno, Kana Higashitani, Hideto Nagai, Ryusuke Yoshimi, Yukie Yamaguchi, Ikuma Kato, Ichiro Aoki, Hideaki Nakajima
Published 2018-06-01

Case Report: Tocilizumab Treatment for VEXAS Syndrome With Relapsing Polychondritis: A Single-Center, 1-Year Longitudinal Observational Study In Japan

by Yosuke Kunishita, Yohei Kirino, Naomi Tsuchida, Naomi Tsuchida, Naomi Tsuchida, Ayaka Maeda, Yuichiro Sato, Kaoru Takase-Minegishi, Ryusuke Yoshimi, Hideaki Nakajima
Published 2022-06-01

TRIM21 Dysfunction Enhances Aberrant B-Cell Differentiation in Autoimmune Pathogenesis

by Yosuke Kunishita, Ryusuke Yoshimi, Reikou Kamiyama, Daiga Kishimoto, Koji Yoshida, Eijin Hashimoto, Takaaki Komiya, Natsuki Sakurai, Yumiko Sugiyama, Yohei Kirino, Keiko Ozato, Hideaki Nakajima
Published 2020-02-01

Dysregulated heme oxygenase-1low M2-like macrophages augment lupus nephritis via Bach1 induced by type I interferons

by Daiga Kishimoto, Yohei Kirino, Maasa Tamura, Mitsuhiro Takeno, Yosuke Kunishita, Kaoru Takase-Minegishi, Hiroto Nakano, Ikuma Kato, Kiyotaka Nagahama, Ryusuke Yoshimi, Kazuhiko Igarashi, Ichiro Aoki, Hideaki Nakajima
Published 2018-04-01

Association of low-dose glucocorticoid use and infection occurrence in systemic lupus erythematosus patients: a prospective cohort study

by Kazuya Abe, Yuichi Ishikawa, Yasuhiko Kita, Nobuyuki Yajima, Eisuke Inoue, Ken-ei Sada, Yoshia Miyawaki, Ryusuke Yoshimi, Yasuhiro Shimojima, Shigeru Ohno, Hiroshi Kajiyama, Kunihiro Ichinose, Shuzo Sato, Michio Fujiwara
Published 2022-07-01

Changes in the proportion of clinical clusters contribute to the phenotypic evolution of Behçet’s disease in Japan

by Yutaro Soejima, Yohei Kirino, Mitsuhiro Takeno, Michiko Kurosawa, Masaki Takeuchi, Ryusuke Yoshimi, Yumiko Sugiyama, Shigeru Ohno, Yukiko Asami, Akiko Sekiguchi, Toshihisa Igarashi, Shohei Nagaoka, Yoshiaki Ishigatsubo, Hideaki Nakajima, Nobuhisa Mizuki
Published 2021-02-01

Association of high disease activity and serum IL-6 levels with the incidence of inflammatory major organ events in Behçet disease: a prospective registry study

by Lisa Hirahara, Yohei Kirino, Yutaro Soejima, Yuki Iizuka, Ryusuke Yoshimi, Yuichiro Fujieda, Tatsuya Atsumi, Toshihiro Tono, Daisuke Kobayashi, Akira Meguro, Masaki Takeuchi, Kentaro Sakamaki, Mitsuhiro Takeno, Nobuhisa Mizuki, Hideaki Nakajima
Published 2024-04-01

Number of Attending Physicians and Accumulated Organ Damage in Patients with Systemic Lupus Erythematosus: LUNA Registry Cross-Sectional Study

by Ryo Yanai, Nobuyuki Yajima, Nao Oguro, Yasuhiro Shimojima, Shigeru Ohno, Hiroshi Kajiyama, Kunihiro Ichinose, Shuzo Sato, Michio Fujiwara, Yoshia Miyawaki, Ryusuke Yoshimi, Takashi Kida, Yusuke Matsuo, Keisuke Nishimura, Ken-ei Sada
Published 2023-01-01

Protective effect of hydroxychloroquine on infections in patients with systemic lupus erythematosus: an observational study using the LUNA registry

by Chiharu Hidekawa, Ryusuke Yoshimi, Ryusuke Yoshimi, Yusuke Saigusa, Jun Tamura, Noriko Kojitani, Naoki Suzuki, Natsuki Sakurai, Yuji Yoshioka, Yumiko Sugiyama-Kawahara, Yosuke Kunishita, Daiga Kishimoto, Kana Higashitani, Yuichiro Sato, Takaaki Komiya, Hideto Nagai, Naoki Hamada, Ayaka Maeda, Naomi Tsuchida, Lisa Hirahara, Yutaro Soejima, Kaoru Takase-Minegishi, Yohei Kirino, Nobuyuki Yajima, Ken-ei Sada, Yoshia Miyawaki, Kunihiro Ichinose, Shigeru Ohno, Hiroshi Kajiyama, Shuzo Sato, Yasuhiro Shimojima, Michio Fujiwara, Hideaki Nakajima
Published 2023-09-01

Rationale and Design of the Orencia Atherosclerosis and Rheumatoid Arthritis Study (ORACLE Arthritis Study): Implications of Biologics against Rheumatoid Arthritis and the Vascular...

by Tomoaki Ishigami, Toshihiro Nanki, Takuya Sugawara, Kotaro Uchida, Hiroyuki Takeda, Tatsuya Sawasaki, Lin Chen, Hiroshi Doi, Kentaro Arakawa, Sae Saigo, Ryusuke Yoshimi, Masataka Taguri, Kazuo Kimura, Kiyoshi Hibi, Hiromichi Wakui, Kengo Azushima, Kouichi Tamura, on behalf of ORACLE Arthritis Investigators
Published 2021-11-01

Association of one-point glucocorticoid-free status with chronic damage and disease duration in systemic lupus erythematosus: a cross-sectional study

by Ken-ei Sada, Hiroshi Kajiyama, Ryusuke Yoshimi, Kunihiro Ichinose, Yoshia Miyawaki, Shigeru Ohno, Nobuyuki Yajima, Keigo Hayashi, Yu Katayama, Yosuke Asano, Keiji Ohashi, Eri Katsuyama, Takayuki Katsuyama, Mariko Takano-Narazaki, Yoshinori Matsumoto, Yasuhiro Shimojima, Shuzo Sato, Michio Fujiwara
Published 2022-03-01

Real-world data on vitamin D supplementation and its impacts in systemic lupus erythematosus: Cross-sectional analysis of a lupus registry of nationwide institutions (LUNA).

by Keigo Hayashi, Ken-Ei Sada, Yosuke Asano, Yu Katayama, Keiji Ohashi, Michiko Morishita, Yoshia Miyawaki, Haruki Watanabe, Takayuki Katsuyama, Mariko Narazaki, Yoshinori Matsumoto, Nobuyuki Yajima, Ryusuke Yoshimi, Yasuhiro Shimojima, Shigeru Ohno, Hiroshi Kajiyama, Kunihiro Ichinose, Shuzo Sato, Michio Fujiwara, Jun Wada
Published 2022-01-01

Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease

by Tatsuma Ban, Masako Kikuchi, Go R. Sato, Akio Manabe, Noriko Tagata, Kayo Harita, Akira Nishiyama, Kenichi Nishimura, Ryusuke Yoshimi, Yohei Kirino, Hideyuki Yanai, Yoshiko Matsumoto, Shuichi Suzuki, Hiroe Hihara, Masashi Ito, Kappei Tsukahara, Kentaro Yoshimatsu, Tadashi Yamamoto, Tadatsugu Taniguchi, Hideaki Nakajima, Shuichi Ito, Tomohiko Tamura
Published 2021-07-01