Mimicking Native Display of CD0873 on Liposomes Augments Its Potency as an Oral Vaccine against <i>Clostridioides difficile</i>

by Cansu Karyal, Panayiota Palazi, Jaime Hughes, Rhys C. Griffiths, Ruby R. Persaud, Patrick J. Tighe, Nicholas J. Mitchell, Ruth Griffin
Published 2021-12-01

Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains the efficacy of immune...

by Siân E. Jossi, Melissa Arcuri, Melissa Arcuri, Areej Alshayea, Ruby R. Persaud, Edith Marcial-Juárez, Elena Palmieri, Roberta Di Benedetto, Marisol Pérez-Toledo, Jamie Pillaye, Will M. Channell, Anna E. Schager, Rachel E. Lamerton, Charlotte N. Cook, Margaret Goodall, Takeshi Haneda, Andreas J. Bäumler, Lucy H. Jackson-Jones, Kai-Michael Toellner, Calman A. MacLennan, Calman A. MacLennan, Ian R. Henderson, Francesca Micoli, Adam F. Cunningham
Published 2023-03-01