UBQLN4 promotes non-homologous end joining by repressing DNA end-resection

by Ron D. Jachimowicz, H. Christian Reinhardt
Published 2019-03-01

Mouse models of diffuse large B cell lymphoma

by Areya Tabatabai, Aastha Arora, Svenja Höfmann, Maximilian Jauch, Bastian von Tresckow, Julia Hansen, Julia Hansen, Julia Hansen, Julia Hansen, Julia Hansen, Ruth Flümann, Ruth Flümann, Ruth Flümann, Ruth Flümann, Ruth Flümann, Ron D. Jachimowicz, Ron D. Jachimowicz, Ron D. Jachimowicz, Ron D. Jachimowicz, Ron D. Jachimowicz, Sebastian Klein, Hans Christian Reinhardt, Gero Knittel
Published 2023-12-01

Targeting DNA Repair, Cell Cycle, and Tumor Microenvironment in B Cell Lymphoma

by Paul J. Bröckelmann, Mathilde R. W. de Jong, Ron D. Jachimowicz
Published 2020-10-01

Genomic Amplification of <i>UBQLN4</i> Is a Prognostic and Treatment Resistance Factor

by Yuta Kobayashi, Matias A. Bustos, Yoshiaki Shoji, Ron D. Jachimowicz, Yosef Shiloh, Dave S. B. Hoon
Published 2022-10-01

Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma

by Tomohiro Murakami, Yoshiaki Shoji, Tomohiko Nishi, Shu‐Ching Chang, Ron D. Jachimowicz, Sojun Hoshimoto, Shigeshi Ono, Yosef Shiloh, Hiroya Takeuchi, Yuko Kitagawa, Dave S. B. Hoon, Matias A. Bustos
Published 2021-04-01

Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer

by Leonie Ratz, Chiara Brambillasca, Leandra Bartke, Maxim A. Huetzen, Jonas Goergens, Orsolya Leidecker, Ron D. Jachimowicz, Marieke van de Ven, Natalie Proost, Bjørn Siteur, Renske de Korte-Grimmerink, Peter Bouwman, Emilia M. Pulver, Roebi de Bruijn, Jörg Isensee, Tim Hucho, Gaurav Pandey, Maarten van Lohuizen, Peter Mallmann, Hans Christian Reinhardt, Jos Jonkers, Julian Puppe
Published 2022-06-01

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer

by Marcel A. Dammert, Johannes Brägelmann, Rachelle R. Olsen, Stefanie Böhm, Niloufar Monhasery, Christopher P. Whitney, Milind D. Chalishazar, Hannah L. Tumbrink, Matthew R. Guthrie, Sebastian Klein, Abbie S. Ireland, Jeremy Ryan, Anna Schmitt, Annika Marx, Luka Ozretić, Roberta Castiglione, Carina Lorenz, Ron D. Jachimowicz, Elmar Wolf, Roman K. Thomas, John T. Poirier, Reinhard Büttner, Triparna Sen, Lauren A. Byers, H. Christian Reinhardt, Anthony Letai, Trudy G. Oliver, Martin L. Sos
Published 2019-08-01