Transient Transfection of Primary Cultured Hepatocytes Using CaPO4/DNA Precipitation

by Frank Gaunitz, Monika Papke, Rolf Gebhardt
Published 1996-05-01

Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells

by Melanie Penke, Susanne Schuster, Theresa Gorski, Rolf Gebhardt, Wieland Kiess, Antje Garten
Published 2017-10-01

Continous, non-invasive monitoring of oxygen consumption in a parallelized microfluidic in vitro system provides novel insight into the response to nutrients and drugs of primary h...

by Marius Busche, Dominik Rabl, Jan Fischer, Christian Schmees, Torsten Mayr, Rolf Gebhardt, Martin Stelzle
Published 2022-01-01

Resveratrol differentially regulates NAMPT and SIRT1 in Hepatocarcinoma cells and primary human hepatocytes.

by Susanne Schuster, Melanie Penke, Theresa Gorski, Stefanie Petzold-Quinque, Georg Damm, Rolf Gebhardt, Wieland Kiess, Antje Garten
Published 2014-01-01

Cyclopamine and Rapamycin Synergistically Inhibit mTOR Signalling in Mouse Hepatocytes, Revealing an Interaction of Hedgehog and mTor Signalling in the Liver

by Luise Spormann, Christiane Rennert, Erik Kolbe, Fritzi Ott, Carolin Lossius, Robert Lehmann, Rolf Gebhardt, Thomas Berg, Madlen Matz-Soja
Published 2020-07-01

Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy

by Stefan Hoehme, Seddik Hammad, Jan Boettger, Brigitte Begher-Tibbe, Petru Bucur, Eric Vibert, Rolf Gebhardt, Jan G. Hengstler, Dirk Drasdo
Published 2023-01-01

Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action.

by Michael Schaab, Henriette Kausch, Juergen Klammt, Marcin Nowicki, Ulf Anderegg, Rolf Gebhardt, Stefan Rose-John, Juergen Scheller, Joachim Thiery, Juergen Kratzsch
Published 2012-01-01

The Diurnal Timing of Starvation Differently Impacts Murine Hepatic Gene Expression and Lipid Metabolism – A Systems Biology Analysis Using Self-Organizing Maps

by Christiane Rennert, Sebastian Vlaic, Eugenia Marbach-Breitrück, Eugenia Marbach-Breitrück, Eugenia Marbach-Breitrück, Carlo Thiel, Susanne Sales, Andrej Shevchenko, Rolf Gebhardt, Madlen Matz-Soja
Published 2018-09-01

Correction: Keratinocytes as Depository of Ammonium-Inducible Glutamine Synthetase: Age- and Anatomy-Dependent Distribution in Human and Rat Skin.

by Lusine Danielyan, Sebastian Zellmer, Stefan Sickinger, Genrich V. Tolstonog, Jürgen Salvetter, Ali Lourhmati, Dieter D. Reissig, Cristoph H. Gleiter, Rolf Gebhardt, Gayane Hrachia Buniatian
Published 2009-01-01

Keratinocytes as depository of ammonium-inducible glutamine synthetase: age- and anatomy-dependent distribution in human and rat skin.

by Lusine Danielyan, Sebastian Zellmer, Stefan Sickinger, Genrich V Tolstonog, Jürgen Salvetter, Ali Lourhmati, Dieter D Reissig, Cristoph H Gleiter, Rolf Gebhardt, Gayane Hrachia Buniatian
Published 2009-01-01

Hepatic Hedgehog Signaling Participates in the Crosstalk between Liver and Adipose Tissue in Mice by Regulating FGF21

by Fritzi Ott, Christiane Körner, Kim Werner, Martin Gericke, Ines Liebscher, Donald Lobsien, Silvia Radrezza, Andrej Shevchenko, Ute Hofmann, Jürgen Kratzsch, Rolf Gebhardt, Thomas Berg, Madlen Matz-Soja
Published 2022-05-01

Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis

by Madlen Matz-Soja, Christiane Rennert, Kristin Schönefeld, Susanne Aleithe, Jan Boettger, Wolfgang Schmidt-Heck, Thomas S Weiss, Amalya Hovhannisyan, Sebastian Zellmer, Nora Klöting, Angela Schulz, Jürgen Kratzsch, Reinhardt Guthke, Rolf Gebhardt
Published 2016-05-01

Central energy metabolism remains robust in acute steatotic hepatocytes challenged by a high free fatty acid load

by Jens Niklas1,*, Anne Bonin1, Stefanie Mangin1, Joachim Bucher1, Stephanie Kopacz2, Madlen Matz-Soja 3, Carlo Thiel3, Rolf Gebhardt3, Ute Hofmann2 & Klaus Mauch1
Published 2012-07-01

Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human

by Erik Kolbe, Susanne Aleithe, Christiane Rennert, Luise Spormann, Fritzi Ott, David Meierhofer, Robert Gajowski, Claus Stöpel, Stefan Hoehme, Michael Kücken, Lutz Brusch, Michael Seifert, Witigo von Schoenfels, Clemens Schafmayer, Mario Brosch, Ute Hofmann, Georg Damm, Daniel Seehofer, Jochen Hampe, Rolf Gebhardt, Madlen Matz-Soja
Published 2019-12-01

Consequences of Amyloid‐β Deficiency for the Liver

by Gayane Hrachia Buniatian, Ute Schwinghammer, Roman Tremmel, Holger Cynis, Thomas S. Weiss, Ralf Weiskirchen, Volker M. Lauschke, Sonia Youhanna, Isbaal Ramos, Maria Valcarcel, Torgom Seferyan, Jens‐Ulrich Rahfeld, Vera Rieckmann, Kathrin Klein, Marine Buadze, Victoria Weber, Valentina Kolak, Rolf Gebhardt, Scott L. Friedman, Ulrike C. Müller, Matthias Schwab, Lusine Danielyan
Published 2024-05-01

Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity.

by Thore Santel, Gabi Pflug, Nasr Y A Hemdan, Angelika Schäfer, Marcus Hollenbach, Martin Buchold, Anja Hintersdorf, Inge Lindner, Andreas Otto, Marina Bigl, Ilka Oerlecke, Antje Hutschenreuther, Ulrich Sack, Klaus Huse, Marco Groth, Claudia Birkemeyer, Wolfgang Schellenberger, Rolf Gebhardt, Mathias Platzer, Thomas Weiss, Mookambeswaran A Vijayalakshmi, Monika Krüger, Gerd Birkenmeier
Published 2008-01-01

Correction: Curcumin Inhibits Glyoxalase 1—A Possible Link to Its Anti-Inflammatory and Anti-Tumor Activity.

by Thore Santel, Gabi Pflug, Nasr Y. A. Hemdan, Angelika Schäfer, Marcus Hollenbach, Martin Buchold, Anja Hintersdorf, Inge Lindner, Andreas Otto, Marina Bigl, Ilka Oerlecke, Antje Hutschenreuter, Ulrich Sack, Klaus Huse, Marco Groth, Claudia Birkemeyer, Wolfgang Schellenberger, Rolf Gebhardt, Mathias Platzer, Thomas Weiss, Mookambeswaran A. Vijayalakshmi, Monika Krüger, Gerd Birkenmeier
Published 2011-01-01

Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver

by Gayane Hrachia Buniatian, Ralf Weiskirchen, Thomas S. Weiss, Ute Schwinghammer, Martin Fritz, Torgom Seferyan, Barbara Proksch, Michael Glaser, Ali Lourhmati, Marine Buadze, Erawan Borkham-Kamphorst, Frank Gaunitz, Christoph H. Gleiter, Thomas Lang, Elke Schaeffeler, Roman Tremmel, Holger Cynis, William H. Frey, Rolf Gebhardt, Scott L. Friedman, Wolfgang Mikulits, Matthias Schwab, Lusine Danielyan
Published 2020-02-01

High Circulating Leptin Receptors with Normal Leptin Sensitivity in Liver-specific Insulin Receptor Knock-out (LIRKO) Mice

by Cohen, Shmuel E., Kokkotou, Efi, Biddinger, Sudha B., Kondo, Tatsuya, Gebhardt, Rolf, Kratzsch, Juergen, Mantzoros, Christos S., Kahn, C. Ronald
Published 2019