Inhibition of choline metabolism in an angioimmunoblastic T-cell lymphoma preclinical model reveals a new metabolic vulnerability as possible target for treatment

by Adrien Krug, Marie Tosolini, Blandine Madji Hounoum, Jean-Jacques Fournié, Roger Geiger, Matteo Pecoraro, Patrick Emond, Philippe Gaulard, François Lemonnier, Jean-Ehrland Ricci, Els Verhoeyen
Published 2024-02-01

577 Engineered non-pathogenic synthetic biotic producing L-arginine synergize with PD-1-based cancer immunotherapy

by Ning Li, Fernando Canale, Camilla Basso, Anna Sokolovska, Michela Perotti, Michael James, Wenjie Jin, Jean-Philippe Theurillat, Daniel Leventhal, Kip West, Jose Lora, Federica Sallusto, Roger Geiger
Published 2020-11-01

Multi-omics analysis of naïve B cells of patients harboring the C104R mutation in TACI

by Neftali Ramirez, Neftali Ramirez, Sara Posadas-Cantera, Sara Posadas-Cantera, Niko Langer, Andres Caballero Garcia de Oteyza, Andres Caballero Garcia de Oteyza, Michele Proietti, Michele Proietti, Michele Proietti, Michele Proietti, Baerbel Keller, Baerbel Keller, Fangwen Zhao, Victoria Gernedl, Matteo Pecoraro, Hermann Eibel, Hermann Eibel, Klaus Warnatz, Klaus Warnatz, Esteban Ballestar, Roger Geiger, Roger Geiger, Claudia Bossen, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher
Published 2022-08-01

Plasma-derived extracellular vesicles released after endurance exercise exert cardioprotective activity through the activation of antioxidant pathways

by Veronica Lisi, Giorgia Senesi, Nadia Bertola, Matteo Pecoraro, Sara Bolis, Alice Gualerzi, Silvia Picciolini, Andrea Raimondi, Cristina Fantini, Elisa Moretti, Attilio Parisi, Paolo Sgrò, Luigi Di Luigi, Roger Geiger, Silvia Ravera, Giuseppe Vassalli, Daniela Caporossi, Carolina Balbi
Published 2023-07-01

Identification of TPM2 and CNN1 as Novel Prognostic Markers in Functionally Characterized Human Colon Cancer-Associated Stromal Cells

by Valentina Mele, Camilla Basso, Valeria Governa, Jesus F. Glaus Garzon, Manuele G. Muraro, Silvio Däster, Christian A. Nebiker, Robert Mechera, Martin Bolli, Alexander Schmidt, Roger Geiger, Giulio C. Spagnoli, Dimitri Christoforidis, Pietro E. Majno, Lubor Borsig, Giandomenica Iezzi
Published 2022-04-01

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer

by Tiziano Bernasocchi, Geniver El Tekle, Marco Bolis, Azzurra Mutti, Arianna Vallerga, Laura P. Brandt, Filippo Spriano, Tanya Svinkina, Marita Zoma, Valentina Ceserani, Anna Rinaldi, Hana Janouskova, Daniela Bossi, Manuela Cavalli, Simone Mosole, Roger Geiger, Ze Dong, Cai-Guang Yang, Domenico Albino, Andrea Rinaldi, Peter Schraml, Simon Linder, Giuseppina M. Carbone, Andrea Alimonti, Francesco Bertoni, Holger Moch, Steven A. Carr, Wilbert Zwart, Marianna Kruithof-de Julio, Mark A. Rubin, Namrata D. Udeshi, Jean-Philippe P. Theurillat
Published 2021-02-01