The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia

by Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A. F. MacLeod
Published 2022-03-01

NKL Homeobox Genes NKX2-3 and NKX2-4 Deregulate Megakaryocytic-Erythroid Cell Differentiation in AML

by Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A. F. MacLeod
Published 2021-10-01

Establishment of the Myeloid TBX-Code Reveals Aberrant Expression of T-Box Gene TBX1 in Chronic Myeloid Leukemia

by Stefan Nagel, Josephine Haake, Claudia Pommerenke, Corinna Meyer, Roderick A. F. MacLeod
Published 2023-12-01

Chromosomal Aberration t(14;17)(q32;q21) Simultaneously Activates HOXB5 and miR10a in Triple-Hit B-Cell Lymphoma

by Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Maren Kaufmann, Roderick A. F. MacLeod
Published 2023-06-01

Establishment of the TALE-code reveals aberrantly activated homeobox gene PBX1 in Hodgkin lymphoma.

by Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A F MacLeod, Hans G Drexler
Published 2021-01-01

Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia.

by Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A F MacLeod, Hans G Drexler
Published 2020-01-01

NKL homeobox gene activities in B-cell development and lymphomas.

by Stefan Nagel, Roderick A F MacLeod, Corinna Meyer, Maren Kaufmann, Hans G Drexler
Published 2018-01-01

Genomic Aberrations Generate Fusion Gene FOXK2::TP63 and Activate NFKB1 in Cutaneous T-Cell Lymphoma

by Stefan Nagel, Claudia Pommerenke, Hilmar Quentmeier, Corinna Meyer, Maren Kaufmann, Roderick A. F. MacLeod
Published 2022-08-01

Aberrantly Expressed OTX Homeobox Genes Deregulate B-Cell Differentiation in Hodgkin Lymphoma.

by Stefan Nagel, Stefan Ehrentraut, Corinna Meyer, Maren Kaufmann, Hans G Drexler, Roderick A F MacLeod
Published 2015-01-01

Aberrant activity of NKL homeobox gene NKX3-2 in a T-ALL subset.

by Stefan Nagel, Corinna Meyer, Maren Kaufmann, Margarete Zaborski, Roderick A F MacLeod, Hans G Drexler
Published 2018-01-01

Inhibition of PI3K/mTOR overcomes nilotinib resistance in BCR-ABL1 positive leukemia cells through translational down-regulation of MDM2.

by Jie Ding, Julia Romani, Margarete Zaborski, Roderick A F MacLeod, Stefan Nagel, Hans G Drexler, Hilmar Quentmeier
Published 2013-01-01

Correction: Ectopic Expression of Homeobox Gene NKX2-1 in Diffuse Large B-Cell Lymphoma Is Mediated by Aberrant Chromatin Modifications

by Stefan Nagel, Stefan Ehrentraut, Jürgen Tomasch, Hilmar Quentmeier, Corinna Meyer, Maren Kaufmann, Hans G. Drexler, Roderick A. F. MacLeod
Published 2013-01-01

High frequency of cryptic chromosomal rearrangements involving the LMO2 gene in T-cell acute lymphoblastic leukemia

by Lili Wu, Yang Xu, Qian Wang, Changgeng Ruan, Hans G. Drexler, Depei Wu, Roderick A. F. MacLeod, Suning Chen
Published 2015-06-01

Ectopic expression of homeobox gene NKX2-1 in diffuse large B-cell lymphoma is mediated by aberrant chromatin modifications.

by Stefan Nagel, Stefan Ehrentraut, Jürgen Tomasch, Hilmar Quentmeier, Corinna Meyer, Maren Kaufmann, Hans G Drexler, Roderick A F MacLeod
Published 2013-01-01

Correction: Ectopic Expression of Homeobox Gene NKX2-1 in Diffuse Large B-Cell Lymphoma Is Mediated by Aberrant Chromatin Modifications.

by Stefan Nagel, Stefan Ehrentraut, Jürgen Tomasch, Hilmar Quentmeier, Corinna Meyer, Maren Kaufmann, Hans G. Drexler, Roderick A. F. MacLeod
Published 2013-01-01

NKL homeobox gene activities in hematopoietic stem cells, T-cell development and T-cell leukemia.

by Stefan Nagel, Claudia Pommerenke, Michaela Scherr, Corinna Meyer, Maren Kaufmann, Karin Battmer, Roderick A F MacLeod, Hans G Drexler
Published 2017-01-01

NKL homeobox gene activities in normal and malignant myeloid cells.

by Stefan Nagel, Michaela Scherr, Roderick A F MacLeod, Claudia Pommerenke, Max Koeppel, Corinna Meyer, Maren Kaufmann, Iris Dallmann, Hans G Drexler
Published 2019-01-01

Transcriptional activation of prostate specific homeobox gene NKX3-1 in subsets of T-cell lymphoblastic leukemia (T-ALL).

by Stefan Nagel, Stefan Ehrentraut, Jürgen Tomasch, Stefan Lienenklaus, Björn Schneider, Robert Geffers, Corinna Meyer, Maren Kaufmann, Hans G Drexler, Roderick A F MacLeod
Published 2012-01-01

Clinical, immunophenotypic, cytogenetic, and molecular genetic features in 117 adult patients with mixed-phenotype acute leukemia defined by WHO-2008 classification

by Lingzhi Yan, Nana Ping, Mingqing Zhu, Aining Sun, Yongquan Xue, Changgeng Ruan, Hans G. Drexler, Roderick A. F. MacLeod, Depei Wu, Suning Chen
Published 2012-11-01

Diffuse Large B Cell Lymphoma Cell Line U-2946: Model for MCL1 Inhibitor Testing.

by Hilmar Quentmeier, Hans G Drexler, Vivien Hauer, Roderick A F MacLeod, Claudia Pommerenke, Cord C Uphoff, Margarete Zaborski, Mattias Berglund, Gunilla Enblad, Rose-Marie Amini
Published 2016-01-01