Polymerase II promoter strength determines efficacy of microRNA adapted shRNAs.

by Robert Jan Lebbink, Maggie Lowe, Theresa Chan, Htet Khine, Xiaoyin Wang, Michael T McManus
Published 2011-01-01

The E3 Ubiquitin Ligase TMEM129 Is a Tri-Spanning Transmembrane Protein

by Michael L. van de Weijer, Guus H. van Muijlwijk, Linda J. Visser, Ana I. Costa, Emmanuel J. H. J. Wiertz, Robert Jan Lebbink
Published 2016-11-01

Proinsulin degradation and presentation of a proinsulin B-chain autoantigen involves ER-associated protein degradation (ERAD)-enzyme UBE2G2

by Tom Cremer, Hanneke Hoelen, Michael L. van de Weijer, George M. Janssen, Ana I. Costa, Peter A. van Veelen, Robert Jan Lebbink, Emmanuel J. H. J. Wiertz
Published 2024-01-01

Mutagenesis of the Varicella-Zoster Virus Genome Demonstrates That VLT and VLT-ORF63 Proteins Are Dispensable for Lytic Infection

by Shirley E. Braspenning, Robert Jan Lebbink, Daniel P. Depledge, Claudia M. E. Schapendonk, Laura A. Anderson, Georges M. G. M. Verjans, Tomohiko Sadaoka, Werner J. D. Ouwendijk
Published 2021-11-01

The purinergic receptor P2X7 as a modulator of viral vector-mediated antigen cross-presentation

by Ylenia Longo, Sara Moreno Mascaraque, Giuseppe Andreacchio, Julia Werner, Ichiro Katahira, Elena De Marchi, Anna Pegoraro, Robert Jan Lebbink, Karl Köhrer, Patrick Petzsch, Ronny Tao, Francesco Di Virgilio, Elena Adinolfi, Ingo Drexler
Published 2024-04-01

Novel chimerized IgA CD20 antibodies: Improving neutrophil activation against CD20-positive malignancies

by Mitchell Evers, Toine Ten Broeke, J.H. Marco Jansen, Maaike Nederend, Firas Hamdan, Karli R. Reiding, Saskia Meyer, Petra Moerer, Iris Brinkman, Thies Rösner, Robert Jan Lebbink, Thomas Valerius, Jeanette H.W. Leusen
Published 2020-01-01

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections.

by Ferdy R van Diemen, Elisabeth M Kruse, Marjolein J G Hooykaas, Carlijn E Bruggeling, Anita C Schürch, Petra M van Ham, Saskia M Imhof, Monique Nijhuis, Emmanuel J H J Wiertz, Robert Jan Lebbink
Published 2016-06-01

RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor

by Zsolt Sebestyen, Wouter Scheper, Anna Vyborova, Siyi Gu, Zuzana Rychnavska, Marleen Schiffler, Astrid Cleven, Coraline Chéneau, Martje van Noorden, Cassie-Marie Peigné, Daniel Olive, Robert Jan Lebbink, Rimke Oostvogels, Tuna Mutis, Gerrit Jan Schuurhuis, Erin J. Adams, Emmanuel Scotet, Jürgen Kuball
Published 2016-05-01

Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.

by Katinka Döhner, Ana Ramos-Nascimento, Dagmara Bialy, Fenja Anderson, Ana Hickford-Martinez, Franziska Rother, Thalea Koithan, Kathrin Rudolph, Anna Buch, Ute Prank, Anne Binz, Stefanie Hügel, Robert Jan Lebbink, Rob C Hoeben, Enno Hartmann, Michael Bader, Rudolf Bauerfeind, Beate Sodeik
Published 2018-01-01

Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.

by Hanneke Hoelen, Arnaud Zaldumbide, Wouter F van Leeuwen, Ellen C W Torfs, Marten A Engelse, Chopie Hassan, Robert Jan Lebbink, Eelco J de Koning, Maaike E Resssing, Arnoud H de Ru, Peter A van Veelen, Rob C Hoeben, Bart O Roep, Emmanuel J H J Wiertz
Published 2015-01-01

Host–Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity

by Angelino T. Tromp, Michiel Van Gent, Joris P. Jansen, Lisette M. Scheepmaker, Anneroos Velthuizen, Carla J.C. De Haas, Kok P.M. Van Kessel, Bart W. Bardoel, Michael Boettcher, Michael T. McManus, Jos A.G. Van Strijp, Robert Jan Lebbink, Pieter-Jan A. Haas, András N. Spaan
Published 2020-02-01

The Epstein-Barr Virus Glycoprotein gp150 Forms an Immune-Evasive Glycan Shield at the Surface of Infected Cells.

by Anna M Gram, Timo Oosenbrug, Marthe F S Lindenbergh, Christian Büll, Anouskha Comvalius, Kathryn J I Dickson, Joop Wiegant, Hans Vrolijk, Robert Jan Lebbink, Ron Wolterbeek, Gosse J Adema, Marieke Griffioen, Mirjam H M Heemskerk, David C Tscharke, Lindsey M Hutt-Fletcher, Emmanuel J H J Wiertz, Rob C Hoeben, Maaike E Ressing
Published 2016-04-01

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

by Christian K. Holm, Stine H. Rahbek, Hans Henrik Gad, Rasmus O. Bak, Martin R. Jakobsen, Zhaozaho Jiang, Anne Louise Hansen, Simon K. Jensen, Chenglong Sun, Martin K. Thomsen, Anders Laustsen, Camilla G. Nielsen, Kasper Severinsen, Yingluo Xiong, Dara L. Burdette, Veit Hornung, Robert Jan Lebbink, Mogens Duch, Katherine A. Fitzgerald, Shervin Bahrami, Jakob Giehm Mikkelsen, Rune Hartmann, Søren R. Paludan
Published 2016-02-01

Global molecular diversity of RSV – the “INFORM RSV” study

by Annefleur C. Langedijk, Robert Jan Lebbink, Christiana Naaktgeboren, Anouk Evers, Marco C. Viveen, Anne Greenough, Terho Heikkinen, Renato T. Stein, Peter Richmond, Federico Martinón-Torres, Marta Nunes, Mitsuaki Hosoya, Christian Keller, Monika Bauck, Robert Cohen, Jesse Papenburg, Jeffrey Pernica, Marije P. Hennus, Hong Jin, David E. Tabor, Andrev Tovchigrechko, Alexey Ruzin, Michael E. Abram, Deidre Wilkins, Joanne G. Wildenbeest, Leyla Kragten-Tabatabaie, Frank E. J. Coenjaerts, Mark T. Esser, Louis J. Bont
Published 2020-06-01

The genomic evolutionary dynamics and global circulation patterns of respiratory syncytial virus

by Annefleur C. Langedijk, Bram Vrancken, Robert Jan Lebbink, Deidre Wilkins, Elizabeth J. Kelly, Eugenio Baraldi, Abiel Homero Mascareñas de Los Santos, Daria M. Danilenko, Eun Hwa Choi, María Angélica Palomino, Hsin Chi, Christian Keller, Robert Cohen, Jesse Papenburg, Jeffrey Pernica, Anne Greenough, Peter Richmond, Federico Martinón-Torres, Terho Heikkinen, Renato T. Stein, Mitsuaki Hosoya, Marta C. Nunes, Charl Verwey, Anouk Evers, Leyla Kragten-Tabatabaie, Marc A. Suchard, Sergei L. Kosakovsky Pond, Chiara Poletto, Vittoria Colizza, Philippe Lemey, Louis J. Bont, on behalf of the INFORM-RSV Study Group
Published 2024-04-01