Sulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines.

by Michelle Visagie, Anne Theron, Thandi Mqoco, Warren Vieira, Renaud Prudent, Anne Martinez, Laurence Lafanechère, Annie Joubert
Published 2013-01-01

A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1.

by Renaud Prudent, Nathalie Demoncheaux, Hélène Diemer, Véronique Collin-Faure, Reuben Kapur, Fabrice Paublant, Laurence Lafanechère, Sarah Cianférani, Thierry Rabilloud
Published 2018-01-01

Characterization of Signalling Pathways That Link Apoptosis and Autophagy to Cell Death Induced by Estrone Analogues Which Reversibly Depolymerize Microtubules

by Anne E. Mercier, Renaud Prudent, Michael S. Pepper, Leanne De Koning, Elsie Nolte, Lauralie Peronne, Marcel Nel, Laurence Lafanechère, Anna M. Joubert
Published 2021-01-01

Preclinical Evaluation of a Novel Small Molecule Inhibitor of LIM Kinases (LIMK) CEL_Amide in Philadelphia-Chromosome Positive (<i>BCR::ABL+</i>) Acute Lymphoblastic Leukemia (ALL)

by Jeannig Berrou, Mélanie Dupont, Hanane Djamai, Emilie Adicéam, Véronique Parietti, Anna Kaci, Emmanuelle Clappier, Jean-Michel Cayuela, André Baruchel, Fabrice Paublant, Renaud Prudent, Jacques Ghysdael, Claude Gardin, Hervé Dombret, Thorsten Braun
Published 2022-11-01

A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity

by Alaa Al Assi, Solène Posty, Frédéric Lamarche, Amel Chebel, Jérôme Guitton, Cécile Cottet-Rousselle, Renaud Prudent, Laurence Lafanechère, Stéphane Giraud, Patrick Dallemagne, Peggy Suzanne, Aurélie Verney, Laurent Genestier, Marie Castets, Eric Fontaine, Marc Billaud, Martine Cordier-Bussat
Published 2024-05-01

Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches

by Emmanuelle Soleilhac, Loraine Brillet-Guéguen, Véronique Roussel, Renaud Prudent, Bastien Touquet, Sheena Dass, Samia Aci-Sèche, Vinod Kasam, Caroline Barette, Anne Imberty, Vincent Breton, Marylin Vantard, Dragos Horvath, Cyrille Botté, Isabelle Tardieux, Sylvaine Roy, Eric Maréchal, Laurence Lafanechère
Published 2018-10-01

Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells

by Lauralie Peronne, Eric Denarier, Ankit Rai, Renaud Prudent, Audrey Vernet, Peggy Suzanne, Sacnicté Ramirez-Rios, Sophie Michallet, Mélanie Guidetti, Julien Vollaire, Daniel Lucena-Agell, Anne-Sophie Ribba, Véronique Josserand, Jean-Luc Coll, Patrick Dallemagne, J. Fernando Díaz, María Ángela Oliva, Karin Sadoul, Anna Akhmanova, Annie Andrieux, Laurence Lafanechère
Published 2020-08-01