Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations wi...

by Brian A Jonas, Carl Johnson, Dita Gratzinger, Ravindra Majeti
Published 2016-01-01

Centrosome-kinase fusions promote oncogenic signaling and disrupt centrosome function in myeloproliferative neoplasms.

by Joanna Y Lee, Wan-Jen Hong, Ravindra Majeti, Tim Stearns
Published 2014-01-01

Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies

by Mark P. Chao, Chris H. Takimoto, Dong Dong Feng, Kelly McKenna, Phung Gip, Jie Liu, Jens-Peter Volkmer, Irving L. Weissman, Ravindra Majeti, Ravindra Majeti
Published 2020-01-01

Preleukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia

by M. Ryan Corces, M. Ryan Corces, Howard Y. Chang, Howard Y. Chang, Ravindra Majeti
Published 2017-11-01

Clonal architecture predicts clinical outcomes and drug sensitivity in acute myeloid leukemia

by Brooks A. Benard, Logan B. Leak, Armon Azizi, Daniel Thomas, Andrew J. Gentles, Ravindra Majeti
Published 2021-12-01

Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6

by Rasmus O Bak, Daniel P Dever, Andreas Reinisch, David Cruz Hernandez, Ravindra Majeti, Matthew H Porteus
Published 2017-09-01

Correction: Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6

by Rasmus O Bak, Daniel P Dever, Andreas Reinisch, David Cruz Hernandez, Ravindra Majeti, Matthew H Porteus
Published 2018-11-01

Convergent epigenetic evolution drives relapse in acute myeloid leukemia

by Kevin Nuno, Armon Azizi, Thomas Koehnke, Caleb Lareau, Asiri Ediriwickrema, M Ryan Corces, Ansuman T Satpathy, Ravindra Majeti
Published 2024-04-01

Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA

by Jin Xu, Kevin Nuno, Ulrike M Litzenburger, Yanyan Qi, M Ryan Corces, Ravindra Majeti, Howard Y Chang
Published 2019-04-01

Treatment advances have not improved the early death rate in acute promyelocytic leukemia

by James Scott McClellan, Holbrook E. Kohrt, Steven Coutre, Jason R. Gotlib, Ravindra Majeti, Ash A. Alizadeh, Bruno C. Medeiros
Published 2012-01-01

The TRACE-Seq method tracks recombination alleles and identifies clonal reconstitution dynamics of gene targeted human hematopoietic stem cells

by Rajiv Sharma, Daniel P. Dever, Ciaran M. Lee, Armon Azizi, Yidan Pan, Joab Camarena, Thomas Köhnke, Gang Bao, Matthew H. Porteus, Ravindra Majeti
Published 2021-01-01

A Dysregulated DNA Methylation Landscape Linked to Gene Expression in MLL-Rearranged AML

by Michael A. Koldobskiy, Jordi Abante, Garrett Jenkinson, Elisabet Pujadas, Ashley Tetens, Feifei Zhao, Rakel Tryggvadottir, Adrian Idrizi, Andreas Reinisch, Ravindra Majeti, John Goutsias, Andrew P. Feinberg
Published 2020-08-01

RUNX1 loss renders hematopoietic and leukemic cells dependent on IL-3 and sensitive to JAK inhibition

by Amy C. Fan, Yusuke Nakauchi, Lawrence Bai, Armon Azizi, Kevin A. Nuno, Feifei Zhao, Thomas Köhnke, Daiki Karigane, David Cruz-Hernandez, Andreas Reinisch, Purvesh Khatri, Ravindra Majeti
Published 2023-10-01

Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential.

by Jie Liu, Lijuan Wang, Feifei Zhao, Serena Tseng, Cyndhavi Narayanan, Lei Shura, Stephen Willingham, Maureen Howard, Susan Prohaska, Jens Volkmer, Mark Chao, Irving L Weissman, Ravindra Majeti
Published 2015-01-01

Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data

by Subarna Sinha, Daniel Thomas, Steven Chan, Yang Gao, Diede Brunen, Damoun Torabi, Andreas Reinisch, David Hernandez, Andy Chan, Erinn B. Rankin, Rene Bernards, Ravindra Majeti, David L. Dill
Published 2017-05-01

CytofIn enables integrated analysis of public mass cytometry datasets using generalized anchors

by Yu-Chen Lo, Timothy J. Keyes, Astraea Jager, Jolanda Sarno, Pablo Domizi, Ravindra Majeti, Kathleen M. Sakamoto, Norman Lacayo, Charles G. Mullighan, Jeffrey Waters, Bita Sahaf, Sean C. Bendall, Kara L. Davis
Published 2022-02-01

Proposed Terminology and Classification of Pre-Malignant Neoplastic Conditions: A Consensus Proposal

by Peter Valent, Cem Akin, Michel Arock, Christoph Bock, Tracy I. George, Stephen J. Galli, Jason Gotlib, Torsten Haferlach, Gregor Hoermann, Olivier Hermine, Ulrich Jäger, Lukas Kenner, Hans Kreipe, Ravindra Majeti, Dean D. Metcalfe, Alberto Orfao, Andreas Reiter, Wolfgang R. Sperr, Philipp B. Staber, Karl Sotlar, Charles Schiffer, Giulio Superti-Furga, Hans-Peter Horny
Published 2017-12-01

Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia

by Mahmoud A. Bassal, Saumya E. Samaraweera, Kelly Lim, Brooks A. Benard, Sheree Bailey, Satinder Kaur, Paul Leo, John Toubia, Chloe Thompson-Peach, Tran Nguyen, Kyaw Ze Ya Maung, Debora A. Casolari, Diana G. Iarossi, Ilaria S. Pagani, Jason Powell, Stuart Pitson, Siria Natera, Ute Roessner, Ian D. Lewis, Anna L. Brown, Daniel G. Tenen, Nirmal Robinson, David M. Ross, Ravindra Majeti, Thomas J. Gonda, Daniel Thomas, Richard J. D’Andrea
Published 2022-07-01

Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia

by Mahmoud A. Bassal, Saumya E. Samaraweera, Kelly Lim, Brooks A. Bernard, Sheree Bailey, Satinder Kaur, Paul Leo, John Toubia, Chloe Thompson-Peach, Tran Nguyen, Kyaw Ze Ya Maung, Debora A. Casolari, Diana G. Iarossi, Ilaria S. Pagani, Jason Powell, Stuart Pitson, Siria Natera, Ute Roessner, Ian D. Lewis, Anna L. Brown, Daniel G. Tenen, Nirmal Robinson, David M. Ross, Ravindra Majeti, Thomas J. Gonda, Daniel Thomas, Richard J. D’Andrea
Published 2022-05-01