SMAC/Diablo controls proliferation of cancer cells by regulating phosphatidylethanolamine synthesis

by Swaroop Kumar Pandey, Avijit Paul, Anna Shteinfer‐Kuzmine, Ran Zalk, Uwe Bunz, Varda Shoshan‐Barmatz
Published 2021-11-01

SAMase of Bacteriophage T3 Inactivates <named-content content-type="genus-species">Escherichia coli</named-content>’s Methionine <italic toggle="yes">S</italic>-Adenosyltransferase...

by Hadas Simon-Baram, Daniel Kleiner, Fannia Shmulevich, Raz Zarivach, Ran Zalk, Huayuan Tang, Feng Ding, Shimon Bershtein
Published 2021-08-01

RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation

by Qi Yuan, Haikel Dridi, Oliver B. Clarke, Steven Reiken, Zephan Melville, Anetta Wronska, Alexander Kushnir, Ran Zalk, Leah Sittenfeld, Andrew R. Marks
Published 2021-11-01

Targeting the Mitochondrial Protein VDAC1 as a Potential Therapeutic Strategy in ALS

by Anna Shteinfer-Kuzmine, Shirel Argueti-Ostrovsky, Marcel F. Leyton-Jaimes, Uttpal Anand, Salah Abu-Hamad, Ran Zalk, Varda Shoshan-Barmatz, Adrian Israelson
Published 2022-09-01

Structural basis for SARM1 inhibition and activation under energetic stress

by Michael Sporny, Julia Guez-Haddad, Tami Khazma, Avraham Yaron, Moshe Dessau, Yoel Shkolnisky, Carsten Mim, Michail N Isupov, Ran Zalk, Michael Hons, Yarden Opatowsky
Published 2020-11-01

Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans

by Tami Khazma, Atira Grossman, Julia Guez-Haddad, Chengye Feng, Hadas Dabas, Radhika Sain, Michal Weitman, Ran Zalk, Michail N. Isupov, Marc Hammarlund, Michael Hons, Yarden Opatowsky
Published 2023-09-01

Structural basis for the intracellular regulation of ferritin degradation

by Fabian Hoelzgen, Thuy T. P. Nguyen, Elina Klukin, Mohamed Boumaiza, Ayush K. Srivastava, Elizabeth Y. Kim, Ran Zalk, Anat Shahar, Sagit Cohen-Schwartz, Esther G. Meyron-Holtz, Fadi Bou-Abdallah, Joseph D. Mancias, Gabriel A. Frank
Published 2024-05-01