Kinetics of Wnt-driven beta-catenin stabilization revealed by quantitative and temporal imaging.

by Rami N Hannoush
Published 2008-01-01

A phage-displayed disulfide constrained peptide discovery platform yields novel human plasma protein binders.

by Xinxin Gao, Harini Kaluarachchi, Yingnan Zhang, Sunhee Hwang, Rami N Hannoush
Published 2024-01-01

Fatty acylation enhances the cellular internalization and cytosolic distribution of a cystine-knot peptide

by Xinxin Gao, Ann De Mazière, Rhiannon Beard, Judith Klumperman, Rami N. Hannoush
Published 2021-11-01

Disulfide-constrained peptide scaffolds enable a robust peptide-therapeutic discovery platform.

by Lijuan Zhou, Fei Cai, Yanjie Li, Xinxin Gao, Yuehua Wei, Anna Fedorova, Daniel Kirchhofer, Rami N Hannoush, Yingnan Zhang
Published 2024-01-01

A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C.

by Robert Mintzer, Sreemathy Ramaswamy, Kinjalkumar Shah, Rami N Hannoush, Christine D Pozniak, Frederick Cohen, Xianrui Zhao, Emile Plise, Joseph W Lewcock, Christopher E Heise
Published 2012-01-01

Cystine-knot peptide inhibitors of HTRA1 bind to a cryptic pocket within the active site region

by Yanjie Li, Yuehua Wei, Mark Ultsch, Wei Li, Wanjian Tang, Benjamin Tombling, Xinxin Gao, Yoana Dimitrova, Christian Gampe, Jakob Fuhrmann, Yingnan Zhang, Rami N. Hannoush, Daniel Kirchhofer
Published 2024-05-01

Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies.

by Yan Gong, Eric Bourhis, Cecilia Chiu, Scott Stawicki, Venita I DeAlmeida, Bob Y Liu, Khanhky Phamluong, Tim C Cao, Richard A D Carano, James A Ernst, Mark Solloway, Bonnee Rubinfeld, Rami N Hannoush, Yan Wu, Paul Polakis, Mike Costa
Published 2010-01-01

Senescent cells perturb intestinal stem cell differentiation through Ptk7 induced noncanonical Wnt and YAP signaling

by Jina Yun, Simon Hansen, Otto Morris, David T. Madden, Clare Peters Libeu, Arjun J. Kumar, Cameron Wehrfritz, Aaron H. Nile, Yingnan Zhang, Lijuan Zhou, Yuxin Liang, Zora Modrusan, Michelle B. Chen, Christopher C. Overall, David Garfield, Judith Campisi, Birgit Schilling, Rami N. Hannoush, Heinrich Jasper
Published 2023-01-01

Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6.

by Christopher E Heise, Jeremy Murray, Katherine E Augustyn, Brandon Bravo, Preeti Chugha, Frederick Cohen, Anthony M Giannetti, Paul Gibbons, Rami N Hannoush, Brian R Hearn, Priyadarshini Jaishankar, Cuong Q Ly, Kinjalkumar Shah, Karen Stanger, Micah Steffek, Yinyan Tang, Xianrui Zhao, Joseph W Lewcock, Adam R Renslo, John Flygare, Michelle R Arkin
Published 2012-01-01

The Small Molecule Dispergo Tubulates the Endoplasmic Reticulum and Inhibits Export

by Lu, Lei, Hannoush, Rami N., Goess, Brian C., Varadarajan, Shankar, Shair, Matthew David, Kirchhausen, Tomas Leopold
Published 2014