Fenofibrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis

by Shaikh Mizanoor Rahman, Ishtiaq Qadri, Rachel C. Janssen, Jacob E. Friedman
Published 2009-11-01

Pediatric Non-Alcoholic Fatty Liver Disease: Nutritional Origins and Potential Molecular Mechanisms

by Ashok Mandala, Rachel C. Janssen, Sirish Palle, Kevin R. Short, Jacob E. Friedman
Published 2020-10-01

Maternal Fat-1 Transgene Protects Offspring from Excess Weight Gain, Oxidative Stress, and Reduced Fatty Acid Oxidation in Response to High-Fat Diet

by Kristen E. Boyle, Margaret J. Magill-Collins, Sean A. Newsom, Rachel C. Janssen, Jacob E. Friedman
Published 2020-03-01

Transgenic increase in N-3/n-6 Fatty Acid ratio reduces maternal obesity-associated inflammation and limits adverse developmental programming in mice.

by Margaret J R Heerwagen, Michael S Stewart, Becky A de la Houssaye, Rachel C Janssen, Jacob E Friedman
Published 2013-01-01

Vertical Transfer of Maternal Gut Microbes to Offspring of Western Diet-Fed Dams Drives Reduced Levels of Tryptophan Metabolites and Postnatal Innate Immune Response

by Kameron Y. Sugino, Rachel C. Janssen, Rachel H. McMahan, Chelsea Zimmerman, Jacob E. Friedman, Karen R. Jonscher
Published 2024-06-01

Maternal Pyrroloquinoline Quinone Supplementation Improves Offspring Liver Bioactive Lipid Profiles throughout the Lifespan and Protects against the Development of Adult NAFLD

by Ashok Mandala, Evgenia Dobrinskikh, Rachel C. Janssen, Oliver Fiehn, Angelo D’Alessandro, Jacob E. Friedman, Karen R. Jonscher
Published 2022-05-01

Isolating mononuclear cells from fetal bone and liver for metabolic, functional, and immunophenotypic analyses in nonhuman primates

by Michael J. Nash, Evgenia Dobrinskikh, Dong Wang, Eric M. Pietras, Rachel C. Janssen, Jacob E. Friedman, Stephanie R. Wesolowski
Published 2024-03-01

Gestational diabetes is characterized by reduced mitochondrial protein expression and altered calcium signaling proteins in skeletal muscle.

by Kristen E Boyle, Hyonson Hwang, Rachel C Janssen, James M DeVente, Linda A Barbour, Teri L Hernandez, Lawrence J Mandarino, Martha Lappas, Jacob E Friedman
Published 2014-01-01

Maternal Western diet exposure increases periportal fibrosis beginning in utero in nonhuman primate offspring

by Michael J. Nash, Evgenia Dobrinskikh, Sean A. Newsom, Ilhem Messaoudi, Rachel C. Janssen, Kjersti M. Aagaard, Carrie E. McCurdy, Maureen Gannon, Paul Kievit, Jacob E. Friedman, Stephanie R. Wesolowski
Published 2021-12-01

Maternal Western diet is associated with distinct preclinical pediatric NAFLD phenotypes in juvenile nonhuman primate offspring

by Michael J. Nash, Evgenia Dobrinskikh, Rachel C. Janssen, Mark A. Lovell, Deborah A. Schady, Claire Levek, Kenneth L. Jones, Angelo D’Alessandro, Paul Kievit, Kjersti M. Aagaard, Carrie E. McCurdy, Maureen Gannon, Jacob E. Friedman, Stephanie R. Wesolowski
Published 2023-02-01

Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants

by Kristen E. Boyle, Zachary W. Patinkin, Allison L.B. Shapiro, Carly Bader, Lauren Vanderlinden, Katerina Kechris, Rachel C. Janssen, Rebecca J. Ford, Brennan K. Smith, Gregory R. Steinberg, Elizabeth J. Davidson, Ivana V. Yang, Dana Dabelea, Jacob E. Friedman
Published 2017-11-01

Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates

by Stephanie R. Wesolowski, Christopher M. Mulligan, Rachel C. Janssen, Peter R. Baker, II, Bryan C. Bergman, Angelo D'Alessandro, Travis Nemkov, Kenneth N. Maclean, Hua Jiang, Tyler A. Dean, Diana L. Takahashi, Paul Kievit, Carrie E. McCurdy, Kjersti M. Aagaard, Jacob E. Friedman
Published 2018-12-01

Gestational Diabetes Is Uniquely Associated With Altered Early Seeding of the Infant Gut Microbiota

by Taylor K. Soderborg, Charles M. Carpenter, Rachel C. Janssen, Tiffany L. Weir, Charles E. Robertson, Diana Ir, Bridget E. Young, Nancy F. Krebs, Teri L. Hernandez, Teri L. Hernandez, Linda A. Barbour, Linda A. Barbour, Daniel N. Frank, Miranda Kroehl, Jacob E. Friedman, Jacob E. Friedman
Published 2020-11-01

Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring

by Michael J. Nash, Evgenia Dobrinskikh, Taylor K. Soderborg, Rachel C. Janssen, Diana L. Takahashi, Tyler A. Dean, Oleg Varlamov, Jon D. Hennebold, Maureen Gannon, Kjersti M. Aagaard, Carrie E. McCurdy, Paul Kievit, Bryan C. Bergman, Kenneth L. Jones, Eric M. Pietras, Stephanie R. Wesolowski, Jacob E. Friedman
Published 2023-04-01

Western diet-induced shifts in the maternal microbiome are associated with altered microRNA expression in baboon placenta and fetal liver

by Kameron Y. Sugino, Ashok Mandala, Rachel C. Janssen, Sunam Gurung, MaJoi Trammell, Michael W. Day, Richard S. Brush, James F. Papin, David W. Dyer, Martin-Paul Agbaga, Martin-Paul Agbaga, Jacob E. Friedman, Jacob E. Friedman, Marisol Castillo-Castrejon, Marisol Castillo-Castrejon, Karen R. Jonscher, Karen R. Jonscher, Dean A. Myers
Published 2022-09-01

The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

by Taylor K. Soderborg, Sarah E. Clark, Christopher E. Mulligan, Rachel C. Janssen, Lyndsey Babcock, Diana Ir, Bridget Young, Nancy Krebs, Dominick J. Lemas, Linda K. Johnson, Tiffany Weir, Laurel L. Lenz, Daniel N. Frank, Teri L. Hernandez, Kristine A. Kuhn, Angelo D’Alessandro, Linda A. Barbour, Karim C. El Kasmi, Jacob E. Friedman
Published 2018-10-01

Author Correction: The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

by Taylor K. Soderborg, Sarah E. Clark, Christopher E. Mulligan, Rachel C. Janssen, Lyndsey Babcock, Diana Ir, Bridget Young, Nancy F. Krebs, Dominick J. Lemas, Linda K. Johnson, Tiffany Weir, Laurel L. Lenz, Daniel N. Frank, Teri L. Hernandez, Kristine A. Kuhn, Angelo D’Alessandro, Linda A. Barbour, Karim C. El Kasmi, Jacob E. Friedman
Published 2019-07-01

Gestational Diabetes Is Characterized by Reduced Mitochondrial Protein Expression and Altered Calcium Signaling Proteins in Skeletal Muscle

by Boyle, Kristen E., Hwang, Hyonson, Janssen, Rachel C., DeVente, James M., Barbour, Linda A., Hernandez, Teri L., Mandarino, Lawrence J., Lappas, Martha, Friedman, Jacob E.
Published 2014