Naturally Occurring Canine Melanoma as a Predictive Comparative Oncology Model for Human Mucosal and Other Triple Wild-Type Melanomas

by Belen Hernandez, Hibret A. Adissu, Bih-Rong Wei, Helen T. Michael, Glenn Merlino, R. Mark Simpson
Published 2018-01-01

Investigation into diagnostic agreement using automated computer-assisted histopathology pattern recognition image analysis

by Joshua D Webster, Aleksandra M Michalowski, Jennifer E Dwyer, Kara N Corps, Bih-Rong Wei, Tarja Juopperi, Shelley B Hoover, R Mark Simpson
Published 2012-01-01

Functional analysis of prognostic gene expression network genes in metastatic breast cancer models.

by Thomas R Geiger, Ngoc-Han Ha, Farhoud Faraji, Helen T Michael, Loren Rodriguez, Renard C Walker, Jeffery E Green, R Mark Simpson, Kent W Hunter
Published 2014-01-01

Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs

by Bih-Rong Wei, Bih-Rong Wei, Cody J. Peer, William J. Richardson, Stephen M. Hewitt, William D. Figg, William D. Figg, R. Mark Simpson
Published 2022-12-01

cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma

by Yunlong He, Wentao Zhu, Min Hwa Shin, Joy Gary, Chengyu Liu, Wendy Dubois, Shelley B. Hoover, Shunlin Jiang, Eryney Marrogi, Beverly Mock, R. Mark Simpson, Jing Huang
Published 2017-06-01

Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence.

by Vanesa C Sanchez, Howard H Yang, Alayna Craig-Lucas, Wendy Dubois, Brandi L Carofino, Justin Lack, Jennifer E Dwyer, R Mark Simpson, Christophe Cataisson, Max P Lee, Ji Luo, Kent W Hunter, Stuart H Yuspa
Published 2022-06-01

Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

by Ruhul Amin, Anjali Shukla, Jacqueline Jufen Zhu, Sohyoung Kim, Ping Wang, Simon Zhongyuan Tian, Andy D. Tran, Debasish Paul, Steven D. Cappell, Sandra Burkett, Huaitian Liu, Maxwell P. Lee, Michael J. Kruhlak, Jennifer E. Dwyer, R. Mark Simpson, Gordon L. Hager, Yijun Ruan, Kent W. Hunter
Published 2021-12-01

CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development

by Etienne S. Melese, Elizabeth Franks, Rachel A. Cederberg, Bryant T. Harbourne, Rocky Shi, Brennan J. Wadsworth, Jenna L. Collier, Elizabeth C. Halvorsen, Fraser Johnson, Jennifer Luu, Min Hee Oh, Vivian Lam, Gerald Krystal, Shelley B. Hoover, Mark Raffeld, R. Mark Simpson, Arun M. Unni, Wan L. Lam, Stephen Lam, Ninan Abraham, Kevin L. Bennewith, William W. Lockwood
Published 2022-01-01

Serum S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients.

by Bih-Rong Wei, Shelley B Hoover, Mark M Ross, Weidong Zhou, Francesco Meani, Jennifer B Edwards, Elizabeth I Spehalski, John I Risinger, W Gregory Alvord, Octavio A Quiñones, Claudio Belluco, Luca Martella, Elio Campagnutta, Antonella Ravaggi, Ren-Ming Dai, Paul K Goldsmith, Kevin D Woolard, Sergio Pecorelli, Lance A Liotta, Emanuel F Petricoin, R Mark Simpson
Published 2009-10-01

Automated computational detection, quantitation, and mapping of mitosis in whole-slide images for clinically actionable surgical pathology decision support

by Munish Puri, Shelley B Hoover, Stephen M Hewitt, Bih-Rong Wei, Hibret Amare Adissu, Charles H C Halsey, Jessica Beck, Charles Bradley, Sarah D Cramer, Amy C Durham, D Glen Esplin, Chad Frank, L Tiffany Lyle, Lawrence D McGill, Melissa D Sánchez, Paula A Schaffer, Ryan P Traslavina, Elizabeth Buza, Howard H Yang, Maxwell P Lee, Jennifer E Dwyer, R Mark Simpson
Published 2019-01-01

Agreement in Histological Assessment of Mitotic Activity Between Microscopy and Digital Whole Slide Images Informs Conversion for Clinical Diagnosis

by Bih-Rong Wei PhD, Charles H. Halsey DVM, PhD, Shelley B. Hoover BS, Munish Puri PhD, Howard H. Yang PhD, Brandon D. Gallas PhD, Maxwell P. Lee PhD, Weijie Chen PhD, Amy C. Durham MS, VMD, Jennifer E. Dwyer MS, Melissa D. Sánchez VMD, PhD, Ryan P. Traslavina DVM, Chad Frank MS, DVM, Charles Bradley VMD, Lawrence D. McGill DVM, PhD, D. Glen Esplin DVM, PhD, Paula A. Schaffer DVM, MS, Sarah D. Cramer DVM, PhD, L. Tiffany Lyle DVM, PhD, Jessica Beck DVM, Elizabeth Buza DVM, Qi Gong MS, Stephen M. Hewitt MD, PhD, R. Mark Simpson DVM, PhD
Published 2019-07-01