Validation and Trustworthiness of Multiscale Models of Cardiac Electrophysiology

by Pras Pathmanathan, Richard A. Gray
Published 2018-02-01

A Parsimonious Model of the Rabbit Action Potential Elucidates the Minimal Physiological Requirements for Alternans and Spiral Wave Breakup.

by Richard A Gray, Pras Pathmanathan
Published 2016-10-01

Evaluation framework for systems models

by Sietse Braakman, Pras Pathmanathan, Helen Moore
Published 2022-03-01

Validation framework for epidemiological models with application to COVID-19 models.

by Kimberly A Dautel, Ephraim Agyingi, Pras Pathmanathan
Published 2023-03-01

A computational modeling framework for pre-clinical evaluation of cardiac mapping systems

by Suran Galappaththige, Pras Pathmanathan, Richard A. Gray
Published 2023-07-01

Modelling the effect of gap junctions on tissue-level cardiac electrophysiology

by Doug Bruce, Pras Pathmanathan, Jonathan P. Whiteley
Published 2012-08-01

Comprehensive Uncertainty Quantification and Sensitivity Analysis for Cardiac Action Potential Models

by Pras Pathmanathan, Jonathan M. Cordeiro, Richard A. Gray
Published 2019-06-01

Advancing Regulatory Science With Computational Modeling for Medical Devices at the FDA's Office of Science and Engineering Laboratories

by Tina M. Morrison, Pras Pathmanathan, Mariam Adwan, Edward Margerrison
Published 2018-09-01

Effect of Heart Structure on Ventricular Fibrillation in the Rabbit: A Simulation Study

by Suran K. Galappaththige, Pras Pathmanathan, Martin J. Bishop, Richard A. Gray
Published 2019-05-01

Credibility assessment of patient-specific computational modeling using patient-specific cardiac modeling as an exemplar

by Suran Galappaththige, Richard A. Gray, Caroline Mendonca Costa, Steven Niederer, Pras Pathmanathan
Published 2022-10-01

Credibility Assessment of a Subject-Specific Mathematical Model of Blood Volume Kinetics for Prediction of Physiological Response to Hemorrhagic Shock and Fluid Resuscitation

by Bahram Parvinian, Ramin Bighamian, Christopher George Scully, Jin-Oh Hahn, Pras Pathmanathan
Published 2021-09-01

Credibility assessment of patient-specific computational modeling using patient-specific cardiac modeling as an exemplar.

by Suran Galappaththige, Richard A Gray, Caroline Mendonca Costa, Steven Niederer, Pras Pathmanathan
Published 2022-10-01

Development and validation of a mathematical model of heart rate response to fluid perturbation

by Varun Kanal, Pras Pathmanathan, Jin-Oh Hahn, George Kramer, Christopher Scully, Ramin Bighamian
Published 2022-12-01

Data-Driven Uncertainty Quantification for Cardiac Electrophysiological Models: Impact of Physiological Variability on Action Potential and Spiral Wave Dynamics

by Pras Pathmanathan, Suran K. Galappaththige, Jonathan M. Cordeiro, Abouzar Kaboudian, Flavio H. Fenton, Richard A. Gray
Published 2020-11-01

Quantitative study of the effect of tissue microstructure on contraction in a computational model of rat left ventricle.

by Valentina Carapella, Rafel Bordas, Pras Pathmanathan, Maelene Lohezic, Jurgen E Schneider, Peter Kohl, Kevin Burrage, Vicente Grau
Published 2014-01-01

Design and execution of a verification, validation, and uncertainty quantification plan for a numerical model of left ventricular flow after LVAD implantation.

by Alfonso Santiago, Constantine Butakoff, Beatriz Eguzkitza, Richard A Gray, Karen May-Newman, Pras Pathmanathan, Vi Vu, Mariano Vázquez
Published 2022-06-01

Credibility Evidence for Computational Patient Models Used in the Development of Physiological Closed-Loop Controlled Devices for Critical Care Medicine

by Bahram Parvinian, Pras Pathmanathan, Chathuri Daluwatte, Farid Yaghouby, Richard A. Gray, Sandy Weininger, Tina M. Morrison, Christopher G. Scully
Published 2019-03-01

Chaste: an open source C++ library for computational physiology and biology.

by Gary R Mirams, Christopher J Arthurs, Miguel O Bernabeu, Rafel Bordas, Jonathan Cooper, Alberto Corrias, Yohan Davit, Sara-Jane Dunn, Alexander G Fletcher, Daniel G Harvey, Megan E Marsh, James M Osborne, Pras Pathmanathan, Joe Pitt-Francis, James Southern, Nejib Zemzemi, David J Gavaghan
Published 2013-01-01