GWAS in IMIDs

by Plenge, Robert M.
Published 2011

Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge

by Plenge, Robert M., Greenberg, Jeffrey D., Mangravite, Lara M., Derry, Jonathan M. J., Stahl, Eli A., Coenen, Marieke J. H., Barton, Anne, Padyukov, Leonid, Klareskog, Lars, Gregersen, Peter K., Mariette, Xavier, Moreland, Larry W., Bridges, S Louis, de Vries, Niek, Huizinga, Tom W. J., Guchelaar, Henk-Jan, Friend, Stephen H., Stolovitzky, Gustavo
Published 2014

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

by Daly, Mark J., Altshuler, David, Xavier, Ramnik J., Sklar, Pamela, Purcell, Shaun M., International Schizophrenia Consortium, Ng, Aylwin C. Y., Scolnick, Edward Mark, Rossin, Elizabeth, Plenge, Robert M., Raychaudhuri, Soumya
Published 2010

Identifying relationships among genomic disease regions: predicting= pathogenic SNP associations and rare deletions

by Raychaudhuri, Soumya, Plenge, Robert M., Rossin, Elizabeth, Ng, Aylwin C. Y., Purcell, Shaun M., Sklar, Pamela, Scolnick, Edward Mark, Xavier, Ramnik J., Altshuler, David, Daly, Mark J.
Published 2010

Data for Genetic Analysis Workshop 16 Problem 1, Association Analysis of Rheumatoid Arthritis Data

by Amos, Christopher I., Chen, Wei Vivien, Seldin, Michael F., Remmers, Elaine F., Taylor, Kimberly E., Criswell, Lindsey A., Lee, Annette T., Plenge, Robert M., Kastner, Daniel L., Gregersen, Peter K.
Published 2013

Analysis and Application of European Genetic Substructure Using 300 K SNP Information

by Tian, Chao, Ransom, Michael, Lee, Annette, Villoslada, Pablo, Selmi, Carlo, Klareskog, Lars, Pulver, Ann E, Qi, Lihong, Gregersen, Peter K, Seldin, Michael F, Plenge, Robert M.
Published 2010

Polygenic Inheritance of Paclitaxel-Induced Sensory Peripheral Neuropathy Driven by Axon Outgrowth Gene Sets in CALGB 40101 (Alliance)

by Chhibber, Aparna, Mefford, Joel, Stahl, Eli A., Pendergrass, Sarah A., Baldwin, R. Michael, Owzar, Kouros, Li, Megan, Winer, Eric P., Hudis, Clifford A., Zembutsu, Hitoshi, Kubo, Michiaki, Nakamura, Yusuke, McLeod, Howard L., Ratain, Mark J., Shulman, Lawrence N., Ritchie, Marylyn D., Plenge, Robert M., Witte, John S., Kroetz, Deanna L.
Published 2015

Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis

by Fernando, Michelle M. A., Stevens, Christine R., Walsh, Emily C., De Jager, Philip Lawrence, Goyette, Philippe, Plenge, Robert M., Vyse, Timothy J., Rioux, John D.
Published 2012

Genomic atlas of the human plasma proteome.

by Sun, Benjamin B, Maranville, Joseph C, Peters, James E, Stacey, David, Staley, James R, Blackshaw, James, Burgess, Stephen, Jiang, Tao, Paige, Ellie, Surendran, Praveen, Oliver-Williams, Clare, Kamat, Mihir A, Prins, Bram P, Wilcox, Sheri K, Zimmerman, Erik S, Chi, An, Bansal, Narinder, Spain, Sarah L, Wood, Angela M, Morrell, Nicholas W, Bradley, John R, Janjic, Nebojsa, Roberts, David J, Ouwehand, Willem H, Todd, John A, Soranzo, Nicole, Suhre, Karsten, Paul, Dirk S, Fox, Caroline S, Plenge, Robert M, Danesh, John, Runz, Heiko, Butterworth, Adam S
Published 2018

High-throughput phenotyping with electronic medical record data using a common semi-supervised approach (PheCAP)

by Zhang, Yichi, Cai, Tianrun, Yu, Sheng, Cho, Kelly, Hong, Chuan, Sun, Jiehuan, Huang, Jie, Ho, Yuk-Lam, Ananthakrishnan, Ashwin N, Xia, Zongqi, Shaw, Stanley Y, Gainer, Vivian, Castro, Victor, Link, Nicholas, Honerlaw, Jacqueline, Huang, Sicong, Gagnon, David, Karlson, Elizabeth W, Plenge, Robert M, Szolovits, Peter, Savova, Guergana, Churchill, Susanne, O’Donnell, Christopher, Murphy, Shawn N, Gaziano, J Michael, Kohane, Isaac, Cai, Tianxi, Liao, Katherine P
Published 2021

PhIP-Seq Characterization of Autoantibodies From Patients With Multiple Sclerosis, Type 1 Diabetes and Rheumatoid Arthritis

by Larman, H. Benjamin, Laserson, Uri, Querol, Luis, Verhaeghen, Katrijn, Solimini, Nicole L., Xu, George, Klarenbeek, Paul L., Church, George, Hafler, David A., Plenge, Robert M., Nigrovic, Peter, De Jager, Philip, Weets, Ilse, Martens, Geert A., O'Connor, Kevin C., Elledge, Stephen
Published 2022

The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1

by Li, Gang, Cunin, Pierre, Wu, Di, Diogo, Dorothée, Yang, Yu, Okada, Yukinori, Plenge, Robert M., Nigrovic, Peter A.
Published 2016

The Influence of Polygenic Risk Scores on Heritability of Anti-CCP Level in RA

by Cui, Jing, Taylor, Kimberly E., Lee, Yvonne C., Källberg, Henrik, Weinblatt, Michael E., Coblyn, Jonathan S., Klareskog, Lars, Criswell, Lindsey A., Gregersen, Peter K., Shadick, Nancy A., Plenge, Robert M., Karlson, Elizabeth W.
Published 2014

Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines

by Yelensky, Roman, Bonakdar, Sasha, Wolfish, Cara S., Cotsapas, Chris, Rivas, Manuel, Dermitzakis, Emmanouil T., Choy, Edwin, Plenge, Robert M., Saxena, Richa, De Jager, Philip Lawrence, Shaw, Stanley Yang, Slavik, Jacqueline Marie, Cahir-McFarland, Ellen D., Kieff, Elliott D., Hafler, David A., Daly, Mark Joseph, Altshuler, David Matthew
Published 2010

Data for Genetic Analysis Workshop (GAW) 15 Problem 2, Genetic Causes of Rheumatoid Arthritis and Associated Traits

by Amos, Christopher I, Remmers, Elaine, Siminovitch, Katherine A, Seldin, Michael F, Criswell, Lindsey A, Lee, Annette T, John, Sally, Shephard, Neil D, Worthington, Jane, Cornelis, Francois, Begovich, Ann B, Dyer, Thomas D, Kastner, Daniel L, Gregersen, Peter K, Plenge, Robert M., Chen, Wei Vivien
Published 2011

Identification of the NF-κB activating protein-like locus as a risk locus for rheumatoid arthritis

by Xie, Gang, Lu, Yue, Sun, Ye, Zhang, Steven Shiyang, Keystone, Edward Clark, Gregersen, Peter K, Plenge, Robert M, Amos, Christopher I, Siminovitch, Katherine A
Published 2014

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.

by Eyre, Steve, Bowes, John, Diogo, Dorothée, Lee, Annette, Barton, Anne, Martin, Paul, Zhernakova, Alexandra, Stahl, Eli, Viatte, Sebastien, McAllister, Kate, Amos, Christopher I, Padyukov, Leonid, Toes, Rene EM, Huizinga, Tom WJ, Wijmenga, Cisca, Trynka, Gosia, Franke, Lude, Westra, Harm-Jan, Alfredsson, Lars, Hu, Xinli, Sandor, Cynthia, de Bakker, Paul IW, Davila, Sonia, Khor, Chiea Chuen, Heng, Khai Koon, Andrews, Robert, Edkins, Sarah, Hunt, Sarah E, Langford, Cordelia, Symmons, Deborah, Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate, Wellcome Trust Case Control Consortium, Concannon, Pat, Onengut-Gumuscu, Suna, Rich, Stephen S, Deloukas, Panos, Gonzalez-Gay, Miguel A, Rodriguez-Rodriguez, Luis, Ärlsetig, Lisbeth, Martin, Javier, Rantapää-Dahlqvist, Solbritt, Plenge, Robert M, Raychaudhuri, Soumya, Klareskog, Lars, Gregersen, Peter K, Worthington, Jane
Published 2021

Similar Risk of Depression and Anxiety Following Surgery or Hospitalization for Crohn's Disease and Ulcerative Colitis

by Ananthakrishnan, Ashwin N, Gainer, Vivian S, Cai, Tianxi, Perez, Raul Guzman, Cheng, Su-Chun, Savova, Guergana, Chen, Pei, Szolovits, Peter, Xia, Zongqi, De Jager, Philip L, Shaw, Stanley, Churchill, Susanne, Karlson, Elizabeth W, Kohane, Isaac, Perlis, Roy H, Plenge, Robert M, Murphy, Shawn N, Liao, Katherine P
Published 2017

Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction

by Klarenbeek, Paul L., Doorenspleet, Marieke E., Esveldt, Rebecca E. E., van Schaik, Barbera D. C., Lardy, Neubury, van Kampen, Antoine H. C., Tak, Paul P., Plenge, Robert M., Baas, Frank, de Bakker, Paul I. W., de Vries, Niek
Published 2015

Quantifying Missing Heritability at Known GWAS Loci

by Gusev, Alexander, Bhatia, Gaurav, Zaitlen, Noah, Vilhjalmsson, Bjarni J., Diogo, Dorothée, Stahl, Eli A., Gregersen, Peter K., Worthington, Jane, Klareskog, Lars, Raychaudhuri, Soumya, Plenge, Robert M., Pasaniuc, Bogdan, Price, Alkes L.
Published 2014