Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon...

by Anna Tikka, Jarkko Soronen, Pirkka‑Pekka Laurila, Jari Metso, Christian Ehnholm, Matti Jauhiainen
Published 2014-12-01

Enhanced vascular permeability facilitates entry of plasma HDL and promotes macrophage-reverse cholesterol transport from skin in mice

by Ilona Kareinen, Lídia Cedó, Reija Silvennoinen, Pirkka-Pekka Laurila, Matti Jauhiainen, Josep Julve, Francisco Blanco-Vaca, Joan Carles Escola-Gil, Petri T. Kovanen, Miriam Lee-Rueckert
Published 2015-02-01

Ryanodine receptor type 1 content decrease‐induced endoplasmic reticulum stress is a hallmark of myopathies

by Jeremy Vidal, Eric A. Fernandez, Martin Wohlwend, Pirkka‐Pekka Laurila, Andrea Lopez‐Mejia, Julien Ochala, Alexander J. Lobrinus, Bengt Kayser, Isabel C. Lopez‐Mejia, Nicolas Place, Nadège Zanou
Published 2023-12-01

Osbpl8 deficiency in mouse causes an elevation of high-density lipoproteins and gender-specific alterations of lipid metabolism.

by Olivier Béaslas, Jari Metso, Eija Nissilä, Pirkka-Pekka Laurila, Essi Kaiharju, Krishna Chaithanya Batchu, Leena Kaipiainen, Mikko I Mäyränpää, Daoguang Yan, Helena Gylling, Matti Jauhiainen, Vesa M Olkkonen
Published 2013-01-01

USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages

by Maija Ruuth, Jarkko Soronen, Essi Kaiharju, Krista Merikanto, Julia Perttilä, Jari Metso, Miriam Lee-Rueckert, Marja-Riitta Taskinen, Petri T. Kovanen, Katariina Öörni, Vesa M. Olkkonen, Matti S. Jauhiainen, Pirkka-Pekka Laurila
Published 2018-12-01

Hematopoietic upstream stimulating factor 1 deficiency is associated with increased atherosclerosis susceptibility in LDL receptor knockout mice

by Menno Hoekstra, Baoyan Ren, Pirkka-Pekka Laurila, Reeni B. Hildebrand, Jarkko Soronen, Vanessa Frodermann, Zhuang Li, Mariëtte R. Boon, Janine J. Geerling, Patrick C. N. Rensen, Matti Jauhiainen, Miranda Van Eck
Published 2021-08-01

Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction

by Martin Wohlwend, Pirkka-Pekka Laurila, Ludger JE Goeminne, Tanes Lima, Ioanna Daskalaki, Xiaoxu Li, Giacomo von Alvensleben, Barbara Crisol, Renata Mangione, Hector Gallart-Ayala, Amélia Lalou, Olivier Burri, Stephen Butler, Jonathan Morris, Nigel Turner, Julijana Ivanisevic, Johan Auwerx
Published 2024-03-01

Correction: Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction

by Martin Wohlwend, Pirkka-Pekka Laurila, Ludger JE Goeminne, Tanes Imamura de lima, Ioanna Daskalaki, Xiaoxu Li, Giacomo von Alvensleben, Barbara Crisol, Renata Mangione, Hector Gallart-Ayala, Amelia Lalou, Olivier Burri, Stephen Butler, Jonathan C Morris, Nigel Turner, Julijana Ivanisevic, Johan Auwerx
Published 2024-05-01

The Contribution of GWAS Loci in Familial Dyslipidemias.

by Pietari Ripatti, Joel T Rämö, Sanni Söderlund, Ida Surakka, Niina Matikainen, Matti Pirinen, Päivi Pajukanta, Antti-Pekka Sarin, Susan K Service, Pirkka-Pekka Laurila, Christian Ehnholm, Veikko Salomaa, Richard K Wilson, Aarno Palotie, Nelson B Freimer, Marja-Riitta Taskinen, Samuli Ripatti
Published 2016-05-01

Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.

by Michael Inouye, Samuli Ripatti, Johannes Kettunen, Leo-Pekka Lyytikäinen, Niku Oksala, Pirkka-Pekka Laurila, Antti J Kangas, Pasi Soininen, Markku J Savolainen, Jorma Viikari, Mika Kähönen, Markus Perola, Veikko Salomaa, Olli Raitakari, Terho Lehtimäki, Marja-Riitta Taskinen, Marjo-Riitta Järvelin, Mika Ala-Korpela, Aarno Palotie, Paul I W de Bakker
Published 2012-01-01

Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis

by Inouye, Michael, Ripatti, Samuli, Kettunen, Johannes, Lyytikäinen, Leo-Pekka, Oksala, Niku, Laurila, Pirkka-Pekka, Kangas, Antti J., Soininen, Pasi, Savolainen, Markku J., Viikari, Jorma, Kähönen, Mika, Perola, Markus, Salomaa, Veikko, Raitakari, Olli, Lehtimäki, Terho, Taskinen, Marja-Riitta, Järvelin, Marjo-Riitta, Ala-Korpela, Mika, Palotie, Aarno, de Bakker, Paul I Wen
Published 2013