The Intricate Epigenetic and Transcriptional Alterations in Pediatric High-Grade Gliomas: Targeting the Crosstalk as the Oncogenic Achilles’ Heel

by Paul Huchedé, Pierre Leblond, Marie Castets
Published 2022-06-01

Elicitation of Antimicrobial Active Compounds by <i>Streptomyces</i>-Fungus Co-Cultures

by Matthieu Nicault, Ali Zaiter, Stéphane Dumarcay, Patrick Chaimbault, Eric Gelhaye, Pierre Leblond, Cyril Bontemps
Published 2021-01-01

Bone Morphogenic Proteins in Pediatric Diffuse Midline Gliomas: How to Make New Out of Old?

by Clément Berthelot, Paul Huchedé, Adrien Bertrand-Chapel, Pierre-Aurélien Beuriat, Pierre Leblond, Marie Castets
Published 2024-03-01

Negative Correlation between Lipid Content and Antibiotic Activity in <i>Streptomyces</i>: General Rule and Exceptions

by Michelle David, Clara Lejeune, Sonia Abreu, Annabelle Thibessard, Pierre Leblond, Pierre Chaminade, Marie-Joelle Virolle
Published 2020-05-01

Mining the Biosynthetic Potential for Specialized Metabolism of a <i>Streptomyces</i> Soil Community

by Matthieu Nicault, Abdoul-Razak Tidjani, Anthony Gauthier, Stéphane Dumarcay, Eric Gelhaye, Cyril Bontemps, Pierre Leblond
Published 2020-05-01

Bevacizumab as Single Agent in Children and Teenagers with Optic Pathway Glioma

by Pierluigi Calò, Nicolas Pianton, Alexandre Basle, Alexandre Vasiljevic, Marc Barritault, Pierre Aurélien Beuriat, Cécile Faure-Conter, Pierre Leblond
Published 2023-02-01

Growth Hormone Replacement Therapy Seems to Be Safe in Children with Low-Grade Midline Glioma: A Series of 124 Cases with Review of the Literature

by Coline Puvilland, Carine Villanueva, Anaëlle Hemmendinger, Laure Kornreich, Iva Gueorguieva, Mélodie-Anne Karnoub, Pierre Aurélien Beuriat, Pierre Leblond
Published 2022-12-01

Massive Gene Flux Drives Genome Diversity between Sympatric <italic toggle="yes">Streptomyces</italic> Conspecifics

by Abdoul-Razak Tidjani, Jean-Noël Lorenzi, Maxime Toussaint, Erwin van Dijk, Delphine Naquin, Olivier Lespinet, Cyril Bontemps, Pierre Leblond
Published 2019-10-01

Evofosfamide Is Effective against Pediatric Aggressive Glioma Cell Lines in Hypoxic Conditions and Potentiates the Effect of Cytotoxic Chemotherapy and Ionizing Radiations

by Quentin Bailleul, Pauline Navarin, Mélanie Arcicasa, Christine Bal-Mahieu, Angel Montero Carcaboso, Xuefen Le Bourhis, Alessandro Furlan, Samuel Meignan, Pierre Leblond
Published 2021-04-01

A single Sfp-type phosphopantetheinyl transferase plays a major role in the biosynthesis of PKS and NRPS derived metabolites in Streptomyces ambofaciens ATCC23877.

by Robert Bunet, Ramona Riclea, Luisa Laureti, Laurence Hôtel, Cédric Paris, Jean-Michel Girardet, Dieter Spiteller, Jeroen S Dickschat, Pierre Leblond, Bertrand Aigle
Published 2014-01-01

Comparative Genomics among Closely Related Streptomyces Strains Revealed Specialized Metabolite Biosynthetic Gene Cluster Diversity

by Cláudia M. Vicente, Annabelle Thibessard, Jean-Noël Lorenzi, Mabrouka Benhadj, Laurence Hôtel, Djamila Gacemi-Kirane, Olivier Lespinet, Pierre Leblond, Bertrand Aigle
Published 2018-10-01

Multiple and variable NHEJ-like genes are involved in resistance to DNA damage in Streptomyces ambofaciens

by Grégory Hoff, Claire Bertrand, Lingli Zhang, Emilie Piotrowski, Ludovic Chipot, Cyril Bontemps, Fabrice Confalonieri, Stephen McGovern, François Lecointe, Annabelle Thibessard, Pierre Leblond
Published 2016-11-01

Genome Analysis of a Variant of <i>Streptomyces coelicolor</i> M145 with High Lipid Content and Poor Ability to Synthetize Antibiotics

by Thierry Dulermo, Clara Lejeune, Ece Aybeke, Sonia Abreu, Jean Bleton, Michelle David, Ariane Deniset-Besseau, Pierre Chaminade, Annabelle Thibessard, Pierre Leblond, Marie-Joelle Virolle
Published 2023-05-01

Mortality in Children with Optic Pathway Glioma Treated with Up-Front BB-SFOP Chemotherapy.

by Josué Rakotonjanahary, Emilie De Carli, Matthieu Delion, Chantal Kalifa, Jacques Grill, François Doz, Pierre Leblond, Anne-Isabelle Bertozzi, Xavier Rialland, Brain Tumor Committee of SFCE
Published 2015-01-01

Prevalence and mobility of integrative and conjugative elements within a Streptomyces natural population

by Caroline Choufa, Abdoul-Razak Tidjani, Abdoul-Razak Tidjani, Anthony Gauthier, Manar Harb, Manar Harb, Julie Lao, Nathalie Leblond-Bourget, Michiel Vos, Pierre Leblond, Cyril Bontemps
Published 2022-09-01

Toward Improved Diagnosis Accuracy and Treatment of Children, Adolescents, and Young Adults With Ependymoma: The International SIOP Ependymoma II Protocol

by Pierre Leblond, Maura Massimino, Martin English, Timothy A. Ritzmann, Lorenza Gandola, Gabriele Calaminus, Sophie Thomas, Sophie Thomas, David Pérol, Julien Gautier, Richard G. Grundy, Didier Frappaz
Published 2022-06-01

Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance

by Clémence Deligne, Johan Hachani, Sophie Duban-Deweer, Samuel Meignan, Pierre Leblond, Angel M. Carcaboso, Yasuteru Sano, Fumitaka Shimizu, Takashi Kanda, Fabien Gosselet, Marie-Pierre Dehouck, Caroline Mysiorek
Published 2020-06-01

Human Radiosensitivity and Radiosusceptibility: What Are the Differences?

by Laura El-Nachef, Joelle Al-Choboq, Juliette Restier-Verlet, Adeline Granzotto, Elise Berthel, Laurène Sonzogni, Mélanie L. Ferlazzo, Audrey Bouchet, Pierre Leblond, Patrick Combemale, Stéphane Pinson, Michel Bourguignon, Nicolas Foray
Published 2021-07-01

Retrospective National “Real Life” Experience of the SFCE with the Metronomic MEMMAT and MEMMAT-like Protocol

by Camille Winnicki, Pierre Leblond, Franck Bourdeaut, Anne Pagnier, Gilles Paluenzela, Pascal Chastagner, Gwenaelle Duhil-De Benaze, Victoria Min, Hélène Sudour-Bonnange, Catherine Piette, Natacha Entz-Werle, Sylvie Chabaud, Nicolas André
Published 2023-02-01

Improved Long-Term Survival of Patients with Recurrent Medulloblastoma Treated with a “MEMMAT-like” Metronomic Antiangiogenic Approach

by Irene Slavc, Lisa Mayr, Natalia Stepien, Johannes Gojo, Maria Aliotti Lippolis, Amedeo A. Azizi, Monika Chocholous, Alicia Baumgartner, Cora S. Hedrich, Stefan Holm, Astrid Sehested, Pierre Leblond, Karin Dieckmann, Christine Haberler, Thomas Czech, Marcel Kool, Andreas Peyrl
Published 2022-10-01