A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors

by Paweletz Cloud, Nagashima Kumiko, Andersen Jannik, Haines Brian, Chenard Melissa, Zhang Theresa, Roberts Brian, Arthur William, Chastain Michael, Frazier Jason, Klinghoffer Rich, Nebozhyn Michael, Loboda Andrey, Lynch Bethany, Feldman Igor, Dai Hongyue, Huang Pearl, Watters James
Published 2010-06-01

Genomic Analysis of Plasma Cell-Free DNA in Patients With Cancer

by Oxnard, Geoffrey Raymond, Paweletz, Cloud, Sholl, Lynette Marie
Published 2017

Embryonic transcription factor SOX9 drives breast cancer endocrine resistance.

by Jeselsohn, Rinath, Cornwell, MacIntosh, Pun, Matthew, Buchwalter, Gilles, Nguyen, Mai, Bango, Clyde, Huang, Ying, Kuang, Yanan, Paweletz, Cloud, Fu, Xiaoyong, Nardone, Agostina, De Angelis, Carmine, Detre, Simone, Dodson, Andrew, Mohammed, Hisham, Carroll, Jason S, Bowden, Michaela, Rao, Prakash, Long, Henry W, Li, Fugen, Dowsett, Mitchell, Schiff, Rachel, Brown, Myles
Published 2019

In situ single cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2+ breast cancer

by Janiszewska, Michalina, Liu, Lin, Almendro, Vanessa, Kuang, Yanan, Paweletz, Cloud, Sakr, Rita A., Weigelt, Britta, Hanker, Ariella B., Chandarlapaty, Sarat, King, Tari A., Reis-Filho, Jorge S., Arteaga, Carlos L., Park, So Yeon, Michor, Franziska, Polyak, Kornelia
Published 2016

Phase II study of tivantinib (ARQ 197) in patients with metastatic triple-negative breast cancer

by Tolaney, Sara M., Tan, Sally, Guo, Hao, Barry, William, Van Allen, Eliezer, Wagle, Nikhil, Brock, Jane, Larrabee, Katherine, Paweletz, Cloud, Ivanova, Elena, Janne, Pasi, Overmoyer, Beth, Wright, John J., Shapiro, Geoffrey I., Winer, Eric P., Krop, Ian E.
Published 2016

Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses.

by Cañadas, Israel, Thummalapalli, Rohit, Kim, Jong Wook, Kitajima, Shunsuke, Jenkins, Russell William, Christensen, Camilla Laulund, Campisi, Marco, Kuang, Yanan, Zhang, Yanxi, Gjini, Evisa, Zhang, Gao, Tian, Tian, Sen, Debattama Rai, Miao, Diana, Imamura, Yu, Thai, Tran, Piel, Brandon, Terai, Hideki, Aref, Amir Reza, Hagan, Timothy, Koyama, Shohei, Watanabe, Masayuki, Baba, Hideo, Adeni, Anika Elise, Lydon, Christine Anne, Tamayo, Pablo, Wei, Zhi, Herlyn, Meenhard, Barbie, Thanh Uyen, Uppaluri, Ravindra, Sholl, Lynnette Marie, Sicinska, Ewa, Sands, Jacob, Rodig, Scott, Wong, Kwok Kin, Paweletz, Cloud Peter, Watanabe, Hideo, Barbie, David Allen
Published 2018

3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade

by Portell, Andrew, Larios, Dalia, Piel, Brandon P., Mathur, Natasha, Zhou, Chensheng, Coakley, Raven Vlahos, Bartels, Alan, Bowden, Michaela, Herbert, Zach, Gilhooley, Sean, Carter, Jacob, Cañadas, Israel, Thai, Tran C., Kitajima, Shunsuke, Chiono, Valeria, Paweletz, Cloud P., Jenkins, Russell W., Aref, Amir Reza, Ivanova, Elena, Campisi, Marco, Hill, Sarah J, Barbie, David, Kamm, Roger Dale
Published 2018

Dacomitinib as first-line treatment in patients with clinically or molecularly selected advanced non-small-cell lung cancer: a multicentre, open-label, phase 2 trial

by Jaenne, Pasi A., Ou, Sai-Hong I., Kim, Dong-Wan, Oxnard, Geoffrey R., Martins, Renato, Kris, Mark G., Dunphy, Frank, Nishio, Makoto, O'Connell, Joseph, Paweletz, Cloud, Taylor, Ian, Zhang, Hui, Goldberg, Zelanna, Mok, Tony
Published 2020