Mitovesicles secreted into the extracellular space of brains with mitochondrial dysfunction impair synaptic plasticity

by Pasquale D’Acunzo, Elentina K. Argyrousi, Jonathan M. Ungania, Yohan Kim, Steven DeRosa, Monika Pawlik, Chris N. Goulbourne, Ottavio Arancio, Efrat Levy
Published 2024-04-01

c-FLIP regulates autophagy by interacting with Beclin-1 and influencing its stability

by Luana Tomaipitinca, Simonetta Petrungaro, Pasquale D’Acunzo, Angelo Facchiano, Amit Dubey, Salvatore Rizza, Federico Giulitti, Eugenio Gaudio, Antonio Filippini, Elio Ziparo, Francesco Cecconi, Claudia Giampietri
Published 2021-07-01

AMBRA1-Mediated Mitophagy Counteracts Oxidative Stress and Apoptosis Induced by Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells

by Anthea Di Rita, Anthea Di Rita, Anthea Di Rita, Pasquale D’Acunzo, Luca Simula, Silvia Campello, Silvia Campello, Flavie Strappazzon, Francesco Cecconi, Francesco Cecconi, Francesco Cecconi
Published 2018-04-01

Reversible induction of mitophagy by an optogenetic bimodular system

by Pasquale D’Acunzo, Flavie Strappazzon, Ignazio Caruana, Giacomo Meneghetti, Anthea Di Rita, Luca Simula, Gerrit Weber, Francesca Del Bufalo, Luisa Dalla Valle, Silvia Campello, Franco Locatelli, Francesco Cecconi
Published 2019-04-01

Cerebellar Kv3.3 potassium channels activate TANK-binding kinase 1 to regulate trafficking of the cell survival protein Hax-1

by Yalan Zhang, Luis Varela, Klara Szigeti-Buck, Adam Williams, Milan Stoiljkovic, Matija Šestan-Peša, Jorge Henao-Mejia, Pasquale D’Acunzo, Efrat Levy, Richard A. Flavell, Tamas L. Horvath, Leonard K. Kaczmarek
Published 2021-03-01

Cocaine perturbs mitovesicle biology in the brain

by Pasquale D'Acunzo, Jonathan M. Ungania, Yohan Kim, Bryana R. Barreto, Steven DeRosa, Monika Pawlik, Stefanie Canals‐Baker, Hediye Erdjument‐Bromage, Audrey Hashim, Chris N. Goulbourne, Thomas A. Neubert, Mariko Saito, Henry Sershen, Efrat Levy
Published 2023-01-01

HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα

by Anthea Di Rita, Angelo Peschiaroli, Pasquale D′Acunzo, Daniela Strobbe, Zehan Hu, Jens Gruber, Mads Nygaard, Matteo Lambrughi, Gerry Melino, Elena Papaleo, Jörn Dengjel, Said El Alaoui, Michelangelo Campanella, Volker Dötsch, Vladimir V. Rogov, Flavie Strappazzon, Francesco Cecconi
Published 2018-09-01