Tuft and Cancer Stem Cell Marker DCLK1: A New Target to Enhance Anti-Tumor Immunity in the Tumor Microenvironment

by Zhiyun Cao, Nathaniel Weygant, Parthasarathy Chandrakesan, Courtney W. Houchen, Jun Peng, Dongfeng Qu
Published 2020-12-01

Differential effects of β-catenin and NF-κB interplay in the regulation of cell proliferation, inflammation and tumorigenesis in response to bacterial infection.

by Parthasarathy Chandrakesan, Laxmi Uma Maheswar Rao Jakkula, Ishfaq Ahmed, Badal Roy, Shrikant Anant, Shahid Umar
Published 2013-01-01

Inflammatory Mediators and Gut Microbial Toxins Drive Colon Tumorigenesis by IL-23 Dependent Mechanism

by Janani Panneerselvam, Venkateshwar Madka, Rajani Rai, Katherine T. Morris, Courtney W. Houchen, Parthasarathy Chandrakesan, Chinthalapally V. Rao
Published 2021-10-01

Elevated doublecortin-like kinase 1 serum levels revert to baseline after therapy in early stage esophageal adenocarcinoma

by Emily M. Christman, Parthasarathy Chandrakesan, Nathaniel Weygant, John T. Maple, William M. Tierney, Kenneth J. Vega, Courtney W. Houchen
Published 2019-03-01

Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis.

by Dongfeng Qu, Nathaniel Weygant, Randal May, Parthasarathy Chandrakesan, Mohammad Madhoun, Naushad Ali, Sripathi M Sureban, Guangyu An, Michael J Schlosser, Courtney W Houchen
Published 2015-01-01

Bufalin Inhibits Tumorigenesis, Stemness, and Epithelial–Mesenchymal Transition in Colorectal Cancer through a C-Kit/Slug Signaling Axis

by Ling Ding, Yuning Yang, Qin Lu, Dongfeng Qu, Parthasarathy Chandrakesan, Hailan Feng, Hong Chen, Xuzheng Chen, Zhuhui Liao, Jian Du, Zhiyun Cao, Nathaniel Weygant
Published 2022-11-01

Dietary Pectin Increases Intestinal Crypt Stem Cell Survival following Radiation Injury.

by Sripathi M Sureban, Randal May, Dongfeng Qu, Parthasarathy Chandrakesan, Nathaniel Weygant, Naushad Ali, Stan A Lightfoot, Kai Ding, Shahid Umar, Michael J Schlosser, Courtney W Houchen
Published 2015-01-01

DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer.

by Sripathi M Sureban, Randal May, Dongfeng Qu, Nathaniel Weygant, Parthasarathy Chandrakesan, Naushad Ali, Stan A Lightfoot, Panayotis Pantazis, Chinthalapally V Rao, Russell G Postier, Courtney W Houchen
Published 2013-01-01

DCLK1 Regulates Tumor Stemness and Cisplatin Resistance in Non-small Cell Lung Cancer via ABCD-Member-4

by Janani Panneerselvam, Priyanga Mohandoss, Ravi Patel, Hamza Gillan, Michael Li, Kirtana Kumar, DangHuy Nguyen, Nathaniel Weygant, Dongfeng Qu, Kamille Pitts, Stanley Lightfoot, Chinthalapally Rao, Courtney Houchen, Michael Bronze, Parthasarathy Chandrakesan
Published 2020-09-01

Correction: Fluvastatin Interferes with Hepatitis C Virus Replication via Microtubule Bundling and a Doublecortin-like Kinase-Mediated Mechanism.

by Naushad Ali, Heba Allam, Ted Bader, Randal May, Kanthesh M. Basalingappa, William L. Berry, Parthasarathy Chandrakesan, Dongfeng Qu, Nathaniel Weygant, Michael S. Bronze, Shahid Umar, Ralf Janknecht, Sripathi M. Sureban, Mark Huycke, Courtney W. Houchen
Published 2013-01-01

Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism.

by Naushad Ali, Heba Allam, Ted Bader, Randal May, Kanthesh M Basalingappa, William L Berry, Parthasarathy Chandrakesan, Dongfeng Qu, Nathaniel Weygant, Michael S Bronze, Shahid Umar, Ralf Janknecht, Sripathi M Sureban, Mark Huycke, Courtney W Houchen
Published 2013-01-01

Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells.

by Dongfeng Qu, Jeremy Johnson, Parthasarathy Chandrakesan, Nathaniel Weygant, Randal May, Nicole Aiello, Andrew Rhim, Lichao Zhao, Wei Zheng, Stanley Lightfoot, Shubham Pant, Jeremy Irvan, Russell Postier, James Hocker, Jay S Hanas, Naushad Ali, Sripathi M Sureban, Guangyu An, Michael J Schlosser, Ben Stanger, Courtney W Houchen
Published 2015-01-01