Molecular Neuroimaging of the Dopamine Transporter as a Patient Enrichment Biomarker for Clinical Trials for Early Parkinson's Disease

by Klaus Romero, Daniela Conrado, Jackson Burton, Timothy Nicholas, Vikram Sinha, Sreeraj Macha, Malidi Ahamadi, Jesse Cedarbaum, John Seibyl, Kenneth Marek, Peter Basseches, Derek Hill, Ed Somer, Jill Gallagher, David T. Dexter, Arthur Roach, Diane Stephenson, for the Critical Path for Parkinson's (CPP) Consortium, the Parkinson's Progression Markers Initiative (PPMI)
Published 2019-05-01

The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort.

by Marek, Kenneth, Chowdhury, Sohini, Siderowf, Andrew, Lasch, Shirley, Coffey, Christopher S, Caspell-Garcia, Chelsea, Simuni, Tanya, Jennings, Danna, Tanner, Caroline M, Trojanowski, John Q, Shaw, Leslie M, Seibyl, John, Schuff, Norbert, Singleton, Andrew, Kieburtz, Karl, Toga, Arthur W, Mollenhauer, Brit, Galasko, Doug, Chahine, Lana M, Weintraub, Daniel, Foroud, Tatiana, Tosun-Turgut, Duygu, Poston, Kathleen, Arnedo, Vanessa, Frasier, Mark, Sherer, Todd, Parkinson's Progression Markers Initiative
Published 2018

Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort.

by Simuni, Tanya, Siderowf, Andrew, Lasch, Shirley, Coffey, Chris S, Caspell-Garcia, Chelsea, Jennings, Danna, Tanner, Caroline M, Trojanowski, John Q, Shaw, Leslie M, Seibyl, John, Schuff, Norbert, Singleton, Andrew, Kieburtz, Karl, Toga, Arthur W, Mollenhauer, Brit, Galasko, Doug, Chahine, Lana M, Weintraub, Daniel, Foroud, Tatiana, Tosun, Duygu, Poston, Kathleen, Arnedo, Vanessa, Frasier, Mark, Sherer, Todd, Chowdhury, Sohini, Marek, Kenneth, Parkinson's Progression Marker Initiative*
Published 2018

Estimating the Evolution of Disease in the Parkinson's Progression Markers Initiative.

by Iddi, Samuel, Li, Dan, Aisen, Paul S, Rafii, Michael S, Litvan, Irene, Thompson, Wesley K, Donohue, Michael C
Published 2018

Estimating the effect of early treatment initiation in Parkinson's disease using observational data

by Heuvel, L. van den, Evers, L., Meinders, M., Post, B., Stiggelbout, A., Heskes, T., Bloem, B., Krijthe, J.
Published 2020

Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study.

by Nalls, Mike A, McLean, Cory Y, Rick, Jacqueline, Eberly, Shirley, Hutten, Samantha J, Gwinn, Katrina, Sutherland, Margaret, Martinez, Maria, Heutink, Peter, Williams, Nigel M, Hardy, John, Gasser, Thomas, Brice, Alexis, Price, T Ryan, Nicolas, Aude, Keller, Margaux F, Molony, Cliona, Gibbs, J Raphael, Chen-Plotkin, Alice, Suh, Eunran, Letson, Christopher, Fiandaca, Massimo S, Mapstone, Mark, Federoff, Howard J, Noyce, Alastair J, Morris, Huw, Van Deerlin, Vivianna M, Weintraub, Daniel, Zabetian, Cyrus, Hernandez, Dena G, Lesage, Suzanne, Mullins, Meghan, Conley, Emily Drabant, Northover, Carrie AM, Frasier, Mark, Marek, Ken, Day-Williams, Aaron G, Stone, David J, Ioannidis, John PA, Singleton, Andrew B, Parkinson's Disease Biomarkers Program and Parkinson's Progression Marker Initiative investigators
Published 2015

Estimating the Effect of Early Treatment Initiation in Parkinson's Disease Using Observational Data

by van den Heuvel, Lieneke (author), Evers, Luc (author), Meinders, Marjan (author), Post, Bart (author), Stiggelbout, Anne (author), Heskes, Tom (author), Bloem, Bastiaan (author), Krijthe, J.H. (author)
Published 2020

Evolution of Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Early Parkinson's Disease.

by Irwin, David J, Fedler, Janel, Coffey, Christopher S, Caspell-Garcia, Chelsea, Kang, Ju Hee, Simuni, Tanya, Foroud, Tatiana, Toga, Arthur W, Tanner, Caroline M, Kieburtz, Karl, Chahine, Lana M, Reimer, Alyssa, Hutten, Samantha, Weintraub, Daniel, Mollenhauer, Brit, Galasko, Douglas R, Siderowf, Andrew, Marek, Kenneth, Trojanowski, John Q, Shaw, Leslie M, Parkinson's Progression Marker Initiative
Published 2020

REM Sleep Behavior and Motor Findings in Parkinson’s Disease: A Cross-sectional Analysis

by Mahajan, Abhimanyu, Rosenthal, Liana S., Gamaldo, Charlene, Salas, Rachel E., Pontone, Gregory M., McCoy, Arita, Umeh, Chizoba, Mari, Zoltan
Published 2014

Regional expression of genes mediating trans-synaptic alpha-synuclein transfer predicts regional atrophy in Parkinson disease.

by Freeze, Benjamin, Acosta, Diana, Pandya, Sneha, Zhao, Yize, Raj, Ashish
Published 2018

Dynamical Role of Pivotal Brain Regions in Parkinson Symptomatology Uncovered with Deep Learning.

by Nguyen, Alex A, Maia, Pedro D, Gao, Xiao, F Damasceno, Pablo, Raj, Ashish
Published 2020

Regional transcriptional architecture of Parkinson's disease pathogenesis and network spread.

by Freeze, Benjamin, Pandya, Sneha, Zeighami, Yashar, Raj, Ashish
Published 2019

Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson's Disease.

by Kremer, Thomas, Taylor, Kirsten I, Siebourg-Polster, Juliane, Gerken, Thomas, Staempfli, Andreas, Czech, Christian, Dukart, Juergen, Galasko, Douglas, Foroud, Tatiana, Chahine, Lana M, Coffey, Christopher S, Simuni, Tanya, Weintraub, Daniel, Seibyl, John, Poston, Kathleen L, Toga, Arthur W, Tanner, Caroline M, Marek, Kenneth, Hutten, Samantha J, Dziadek, Sebastian, Trenkwalder, Claudia, Pagano, Gennaro, Mollenhauer, Brit
Published 2021

Predictive ability of cerebrospinal fluid biomarkers in diagnosing and evaluating Parkinson's disease

by Wang, Michelle J
Published 2014

Predictors of time to initiation of symptomatic therapy in early Parkinson's disease.

by Simuni, Tanya, Long, Jeffrey D, Caspell-Garcia, Chelsea, Coffey, Christopher S, Lasch, Shirley, Tanner, Caroline M, Jennings, Danna, Kieburtz, Karl D, Marek, Kenneth, PPMI Investigators
Published 2016

Cognition among individuals along a spectrum of increased risk for Parkinson’s disease

by Chahine, Lana M., Urbe, Liz, Caspell-Garcia, Chelsea, Aarsland, Dag, Alcalay, Roy Nissim, Barone, Paolo, Burn, David, Espay, Alberto J., Hamilton, Jamie L., Hawkins, Keith A., Lasch, Shirley, Leverenz, James B., Litvan, Irene, Richard, Irene, Siderowf, Andrew, Coffey, Christopher S., Simuni, Tanya, Weintraub, Daniel, Parkinson’s Progression Markers Initiative
Published 2018

Neuropsychiatric symptoms and cognitive abilities over the initial quinquennium of Parkinson disease.

by Weintraub, Daniel, Caspell-Garcia, Chelsea, Simuni, Tanya, Cho, Hyunkeun R, Coffey, Christopher S, Aarsland, Dag, Alcalay, Roy N, Barrett, Matthew J, Chahine, Lana M, Eberling, Jamie, Espay, Alberto J, Hamilton, Jamie, Hawkins, Keith A, Leverenz, James, Litvan, Irene, Richard, Irene, Rosenthal, Liana S, Siderowf, Andrew, York, Michele, Parkinson’s Progression Markers Initiative
Published 2020

Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression.

by Mollenhauer, Brit, Dakna, Mohammed, Kruse, Niels, Galasko, Douglas, Foroud, Tatiana, Zetterberg, Henrik, Schade, Sebastian, Gera, Roland G, Wang, Wenting, Gao, Feng, Frasier, Mark, Chahine, Lana M, Coffey, Christopher S, Singleton, Andrew B, Simuni, Tanya, Weintraub, Daniel, Seibyl, John, Toga, Arthur W, Tanner, Caroline M, Kieburtz, Karl, Marek, Kenneth, Siderowf, Andrew, Cedarbaum, Jesse M, Hutten, Samantha J, Trenkwalder, Claudia, Graham, Danielle
Published 2020

Data-Driven Subtyping of Parkinson's Disease Using Longitudinal Clinical Records: A Cohort Study.

by Zhang, Xi, Chou, Jingyuan, Liang, Jian, Xiao, Cao, Zhao, Yize, Sarva, Harini, Henchcliffe, Claire, Wang, Fei
Published 2019

Modeling progression of Parkinson's disease

by Ji, Christina X.(Christina Xinyue)
Published 2020