Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

by Jun Fang, Jinping Jia, Matthew Makowski, Mai Xu, Zhaoming Wang, Tongwu Zhang, Jason W. Hoskins, Jiyeon Choi, Younghun Han, Mingfeng Zhang, Janelle Thomas, Michael Kovacs, Irene Collins, Marta Dzyadyk, Abbey Thompson, Maura O'Neill, Sudipto Das, Qi Lan, Roelof Koster, PanScan Consortium, TRICL Consortium, GenoMEL Consortium, Rachael S. Stolzenberg-Solomon, Peter Kraft, Brian M. Wolpin, Pascal W. T. C. Jansen, Sara Olson, Katherine A. McGlynn, Peter A. Kanetsky, Nilanjan Chatterjee, Jennifer H. Barrett, Alison M. Dunning, John C. Taylor, Julia A. Newton-Bishop, D. Timothy Bishop, Thorkell Andresson, Gloria M. Petersen, Christopher I. Amos, Mark M. Iles, Katherine L. Nathanson, Maria Teresa Landi, Michiel Vermeulen, Kevin M. Brown, Laufey T. Amundadottir
Published 2017-04-01

Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies.

by Katherine S Elliott, Eleftheria Zeggini, Mark I McCarthy, Julius Gudmundsson, Patrick Sulem, Simon N Stacey, Steinunn Thorlacius, Laufey Amundadottir, Henrik Grönberg, Jianfeng Xu, Valerie Gaborieau, Rosalind A Eeles, David E Neal, Jenny L Donovan, Freddie C Hamdy, Kenneth Muir, Shih-Jen Hwang, Margaret R Spitz, Brent Zanke, Luis Carvajal-Carmona, Kevin M Brown, Australian Melanoma Family Study Investigators, Nicholas K Hayward, Stuart Macgregor, Ian P M Tomlinson, Mathieu Lemire, Christopher I Amos, Joanne M Murabito, William B Isaacs, Douglas F Easton, Paul Brennan, PanScan Consortium, Rosa B Barkardottir, Daniel F Gudbjartsson, Thorunn Rafnar, David J Hunter, Stephen J Chanock, Kari Stefansson, John P A Ioannidis
Published 2010-05-01

Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data.

by Jianxin Shi, Ju-Hyun Park, Jubao Duan, Sonja T Berndt, Winton Moy, Kai Yu, Lei Song, William Wheeler, Xing Hua, Debra Silverman, Montserrat Garcia-Closas, Chao Agnes Hsiung, Jonine D Figueroa, Victoria K Cortessis, Núria Malats, Margaret R Karagas, Paolo Vineis, I-Shou Chang, Dongxin Lin, Baosen Zhou, Adeline Seow, Keitaro Matsuo, Yun-Chul Hong, Neil E Caporaso, Brian Wolpin, Eric Jacobs, Gloria M Petersen, Alison P Klein, Donghui Li, Harvey Risch, Alan R Sanders, Li Hsu, Robert E Schoen, Hermann Brenner, MGS (Molecular Genetics of Schizophrenia) GWAS Consortium, GECCO (The Genetics and Epidemiology of Colorectal Cancer Consortium), GAME-ON/TRICL (Transdisciplinary Research in Cancer of the Lung) GWAS Consortium, PRACTICAL (PRostate cancer AssoCiation group To Investigate Cancer Associated aLterations) Consortium, PanScan Consortium, GAME-ON/ELLIPSE Consortium, Rachael Stolzenberg-Solomon, Pablo Gejman, Qing Lan, Nathaniel Rothman, Laufey T Amundadottir, Maria Teresa Landi, Douglas F Levinson, Stephen J Chanock, Nilanjan Chatterjee
Published 2016-12-01

Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data

by Shi J., Park J.-H., Duan J., Berndt S.T., Moy W., Yu K., Song L., Wheeler W., Hua X., Silverman D., Garcia-Closas M., Hsiung C.A., Figueroa J.D., Cortessis V.K., Malats N., Karagas M.R., Vineis P., Chang I.-S., Lin D., Zhou B., Seow A., Matsuo K., Hong Y.-C., Caporaso N.E., Wolpin B., Jacobs E., Petersen G.M., Klein A.P., Li D., Risch H., Sanders A.R., Hsu L., Schoen R.E., Brenner H., MGS (Molecular Genetics of Schizophrenia) GWAS Consortium, GECCO (The Genetics and Epidemiology of Colorectal Cancer Consortium), The GAME-ON/TRICL (Transdisciplinary Research in Cancer of the Lung) GWAS Consortium, PRACTICAL (PRostate cancer AssoCiation group To Investigate Cancer Associated aLterations) Consortium, PanScan Consortium, The GAME-ON/ELLIPSE Consortium, Stolzenberg-Solomon R., Gejman P., Lan Q., Rothman N., Amundadottir L.T., Landi M.T., Levinson D.F., Chanock S.J., Chatterjee N.
Published 2018

Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

by Fang, J., Jia, J.P., Makowski, M., Xu, M., Wang, Z.M., Zhang, T.W., Hoskins, J.W., Choi, J., Han, Y.H., Zhang, M.F., Thomas, J., Kovacs, M., Collins, I., Dzyadyk, M., Thompson, A., O'Neill, M., , S. das, Lan, Q., Koster, R., Stolzenberg-Solomon, R.S., Kraft, P., Wolpin, B.M., Jansen, P.W.T.C., Olson, S., McGlynn, K.A., Kanetsky, P.A., Chatterjee, N., Barrett, J.H., Dunning, A.M., Taylor, J.C., Newton-Bishop, J.A., Bishop, D.T., Andresson, T., Petersen, G.M., Amos, C.I., Iles, M.M., Nathanson, K.L., Landi, M.T., Vermeulen, M., Brown, K.M., Amundadottir, L.T., PanScan Consortium, TRICL Consortium, GenoMel Consortium
Published 2017

Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies.

by Elliott, Katherine S, Zeggini, Eleftheria, McCarthy, Mark I, Gudmundsson, Julius, Sulem, Patrick, Stacey, Simon N, Thorlacius, Steinunn, Amundadottir, Laufey, Grönberg, Henrik, Xu, Jianfeng, Gaborieau, Valerie, Eeles, Rosalind A, Neal, David E, Donovan, Jenny L, Hamdy, Freddie C, Muir, Kenneth, Hwang, Shih-Jen, Spitz, Margaret R, Zanke, Brent, Carvajal-Carmona, Luis, Brown, Kevin M, Australian Melanoma Family Study Investigators, Hayward, Nicholas K, Macgregor, Stuart, Tomlinson, Ian PM, Lemire, Mathieu, Amos, Christopher I, Murabito, Joanne M, Isaacs, William B, Easton, Douglas F, Brennan, Paul, PanScan Consortium, Barkardottir, Rosa B, Gudbjartsson, Daniel F, Rafnar, Thorunn, Hunter, David J, Chanock, Stephen J, Stefansson, Kari, Ioannidis, John PA
Published 2010

An absolute risk model to identify individuals at elevated risk for pancreatic cancer in the general population

by Klein, A, Lindström, S, Mendelsohn, J, Steplowski, E, Arslan, A, Bueno-De-Mesquita, H, Fuchs, C, Gallinger, S, Gross, M, Helzlsouer, K, Holly, E, Jacobs, E, Lacroix, A, Li, D, Mandelson, M, Olson, S, Petersen, G, Risch, H, Stolzenberg-Solomon, R, Zheng, W, Amundadottir, L, Albanes, D, Allen, N, Bamlet, W, Boutron-Ruault, M, Buring, J, Bracci, P, Canzian, F, Clipp, S, Cotterchio, M, Duell, E, Elena, J, Gaziano, J, Giovannucci, E, Goggins, M, Hallmans, G, Hassan, M, Hutchinson, A, Hunter, D, Kooperberg, C, Kurtz, R, Liu, S, Overvad, K, Palli, D, Patel, A, Rabe, K, Shu, X, Slimani, N, Tobias, G, Trichopoulos, D, Van Den Eeden, S, Vineis, P, Virtamo, J, Wactawski-Wende, J, Wolpin, B, Yu, H, Yu, K, Zeleniuch-Jacquotte, A, Chanock, S, Hoover, R, Hartge, P, Kraft, P
Published 2016

Evaluation of Association of HNF1B Variants with Diverse Cancers: Collaborative Analysis of Data from 19 Genome-Wide Association Studies

by Elliott, Katherine S., Zeggini, Eleftheria, McCarthy, Mark I., Gudmundsson, Julius, Sulem, Patrick, Stacey, Simon N., Thorlacius, Steinunn, Amundadottir, Laufey, Grönberg, Henrik, Xu, Jianfeng, Gaborieau, Valerie, Eeles, Rosalind A., Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Muir, Kenneth, Hwang, Shih-Jen, Spitz, Margaret R., Zanke, Brent, Carvajal-Carmona, Luis, Brown, Kevin M., Hayward, Nicholas K., Macgregor, Stuart, Tomlinson, Ian P. M., Lemire, Mathieu, Amos, Christopher I., Murabito, Joanne M., Isaacs, William B., Easton, Douglas F., Brennan, Paul, Barkardottir, Rosa B., Gudbjartsson, Daniel F., Rafnar, Thorunn, Chanock, Stephen J., Stefansson, Kari, Australian Melanoma Family Study Investigators, The PanScan Consortium, Hunter, David J., Ioannidis, John
Published 2010

An Absolute Risk Model to Identify Individuals at Elevated Risk for Pancreatic Cancer in the General Population

by Klein, Alison P., Lindström, Sara, Mendelsohn, Julie B., Steplowski, Emily, Arslan, Alan A., Bueno-de-Mesquita, H. Bas, Fuchs, Charles S., Gallinger, Steven, Gross, Myron, Helzlsouer, Kathy, Holly, Elizabeth A., Jacobs, Eric J., LaCroix, Andrea, Li, Donghui, Mandelson, Margaret T., Olson, Sara H., Petersen, Gloria M., Risch, Harvey A., Stolzenberg-Solomon, Rachael Z., Zheng, Wei, Amundadottir, Laufey, Albanes, Demetrius, Allen, Naomi E., Bamlet, William R., Boutron-Ruault, Marie-Christine, Buring, Julie E., Bracci, Paige M., Canzian, Federico, Clipp, Sandra, Cotterchio, Michelle, Duell, Eric J., Elena, Joanne, Gaziano, J. Michael, Giovannucci, Edward L., Goggins, Michael, Hallmans, Göran, Hassan, Manal, Hutchinson, Amy, Hunter, David J., Kooperberg, Charles, Kurtz, Robert C., Liu, Simin, Overvad, Kim, Palli, Domenico, Patel, Alpa V., Rabe, Kari G., Shu, Xiao-Ou, Slimani, Nadia, Tobias, Geoffrey S., Trichopoulos, Dimitrios, Van Den Eeden, Stephen K., Vineis, Paolo, Virtamo, Jarmo, Wactawski-Wende, Jean, Wolpin, Brian M., Yu, Herbert, Yu, Kai, Zeleniuch-Jacquotte, Anne, Chanock, Stephen J., Hoover, Robert N., Hartge, Patricia, Kraft, Peter
Published 2014