A unifying framework for evaluating the predictive power of genetic variants based on the level of heritability explained.

by Hon-Cheong So, Pak C Sham
Published 2010-12-01

SNPTracker: A Swift Tool for Comprehensive Tracking and Unifying dbSNP rs IDs and Genomic Coordinates of Massive Sequence Variants

by Jia-En Deng, Pak C. Sham, Miao-Xin Li
Published 2016-01-01

The genetic basis of onset age in schizophrenia: evidence and models

by Na Zhan, Pak C. Sham, Pak C. Sham, Pak C. Sham, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Simon S. Y. Lui
Published 2023-06-01

Abnormal Brain Structure Morphology in Early-Onset Schizophrenia

by Jia Cai, Wei Wei, Liansheng Zhao, Mingli Li, Xiaojing Li, Sugai Liang, Wei Deng, Xiang Dong Du, Qiang Wang, Wan-jun Guo, Xiaohong Ma, Pak C. Sham, Pak C. Sham, Pak C. Sham, Tao Li, Tao Li
Published 2022-07-01

Immune dysregulation in depression: Evidence from genome-wide association

by Justin D. Tubbs, Jiahong Ding, Larry Baum, Pak C. Sham
Published 2020-08-01

Chronic Ketamine Exposure Causes White Matter Microstructural Abnormalities in Adolescent Cynomolgus Monkeys

by Qi Li, Qi Li, Qi Li, Lin Shi, Lin Shi, Gang Lu, Hong-Luan Yu, Fu-Ki Yeung, Nai-Kei Wong, Lin Sun, Kai Liu, David Yew, Fang Pan, De-Feng Wang, Pak C. Sham, Pak C. Sham, Pak C. Sham
Published 2017-05-01

A knowledge-based weighting framework to boost the power of genome-wide association studies.

by Miao-Xin Li, Pak C Sham, Stacey S Cherny, You-Qiang Song
Published 2010-01-01

Common and rare variant associations with latent traits underlying depression, bipolar disorder, and schizophrenia

by Saloni Dattani, Pak C. Sham, Bradley S. Jermy, Jonathan R. I. Coleman, David M. Howard, Cathryn M. Lewis
Published 2023-02-01

MaGIC: a program to generate targeted marker sets for genome-wide association studies

by Claire L. Simpson, Valerie K. Hansen, Pak C. Sham, Andrew Collins, John F. Powell, Ammar Al-Chalabi
Published 2004-12-01

Strategies for the study of neuropsychiatric disorders using endophenotypes in developing countries: a potential databank from China

by Raymond C Chan, Raymond C Chan, Irving I Gottesman, Irving I Gottesman, Xiaojia Ge, Pak C Sham
Published 2010-10-01

Predicting mendelian disease-causing non-synonymous single nucleotide variants in exome sequencing studies.

by Miao-Xin Li, Johnny S H Kwan, Su-Ying Bao, Wanling Yang, Shu-Leong Ho, Yong-Qiang Song, Pak C Sham
Published 2013-01-01

MRI study of minor physical anomaly in childhood autism implicates aberrant neurodevelopment in infancy.

by Charlton Cheung, Grainne M McAlonan, Yee Y Fung, Germaine Fung, Kevin K Yu, Kin-Shing Tai, Pak C Sham, Siew E Chua
Published 2011-01-01

Interleukin-18 levels in the hippocampus and behavior of adult rat offspring exposed to prenatal restraint stress during early and late pregnancy

by Mo-Xian Chen, Qiang Liu, Shu Cheng, Lei Lei, Ai-Jin Lin, Ran Wei, Tomy C K. Hui, Qi Li, Li-Juan Ao, Pak C Sham
Published 2020-01-01

Prenatal immune challenge is an environmental risk factor for brain and behavior change relevant to schizophrenia: evidence from MRI in a mouse model.

by Qi Li, Charlton Cheung, Ran Wei, Edward S Hui, Joram Feldon, Urs Meyer, Sookja Chung, Siew E Chua, Pak C Sham, Ed X Wu, Grainne M McAlonan
Published 2009-01-01

Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs.

by Liang-Dar Hwang, Justin D Tubbs, Justin Luong, Mischa Lundberg, Gunn-Helen Moen, Geng Wang, Nicole M Warrington, Pak C Sham, Gabriel Cuellar-Partida, David M Evans
Published 2020-10-01

Dysfunction of Myosin Light‐Chain 4 (MYL4) Leads to Heritable Atrial Cardiomyopathy With Electrical, Contractile, and Structural Components: Evidence From Genetically‐Engineered Ra...

by Wenhui Peng, Miaoxin Li, Hailing Li, Kai Tang, Jianhui Zhuang, Jianguo Zhang, Jingjing Xiao, Hui Jiang, Dali Li, Yongchun Yu, Pak C. Sham, Stanley Nattel, Yawei Xu
Published 2017-11-01

Interplay between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study.

by Antonella Trotta, Conrad Iyegbe, Marta Di Forti, Pak C Sham, Desmond D Campbell, Stacey S Cherny, Valeria Mondelli, Katherine J Aitchison, Robin M Murray, Evangelos Vassos, Helen L Fisher
Published 2016-01-01

Genome-wide association analysis with gray matter volume as a quantitative phenotype in first-episode treatment-naïve patients with schizophrenia.

by Qiang Wang, Bo Xiang, Wei Deng, Junyao Wu, Mingli Li, Xiaohong Ma, Yingcheng Wang, Lijun Jiang, Grainne McAlonan, Siew E Chua, Pak C Sham, Xun Hu, Tao Li
Published 2013-01-01

DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics

by Vivian Tam, Peikai Chen, Anita Yee, Nestor Solis, Theo Klein, Mateusz Kudelko, Rakesh Sharma, Wilson CW Chan, Christopher M Overall, Lisbet Haglund, Pak C Sham, Kathryn Song Eng Cheah, Danny Chan
Published 2020-12-01

Haplotype analysis reveals a possible founder effect of RET mutation R114H for Hirschsprung's disease in the Chinese population.

by Belinda K Cornes, Clara S Tang, Thomas Y Y Leon, Kenneth J W S Hui, Man-Ting So, Xiaoping Miao, Stacey S Cherny, Pak C Sham, Paul K H Tam, Maria-Merce Garcia-Barcelo
Published 2010-01-01