No evidence for activation of TH1 or TH17 pathways in unstimulated peripheral blood mononuclear cells from children with β-cell autoimmunity or T1D

by Jenny Walldén, Jarno Honkanen, Jorma Ilonen, Johnny Ludvigsson, Outi Vaarala
Published 2008-09-01

Bronchial extracellular matrix from COPD patients induces altered gene expression in repopulated primary human bronchial epithelial cells

by Ulf Hedström, Oskar Hallgren, Lisa Öberg, Amy DeMicco, Outi Vaarala, Gunilla Westergren-Thorsson, Xiaohong Zhou
Published 2018-02-01

The increased risk for autoimmune diseases in patients with eating disorders.

by Anu Raevuori, Jari Haukka, Outi Vaarala, Jaana M Suvisaari, Mika Gissler, Marjut Grainger, Milla S Linna, Jaana T Suokas
Published 2014-01-01

Dendritic cells from Crohn's disease patients show aberrant STAT1 and STAT3 signaling.

by Janne K Nieminen, Mirja Niemi, Taina Sipponen, Harri M Salo, Paula Klemetti, Martti Färkkilä, Jukka Vakkila, Outi Vaarala
Published 2013-01-01

MEK inhibition drives anti-viral defence in RV but not RSV challenged human airway epithelial cells through AKT/p70S6K/4E-BP1 signalling

by Engin Baturcam, Stefan Vollmer, Holger Schlüter, Rose A. Maciewicz, Nisha Kurian, Outi Vaarala, Stephan Ludwig, Danen Mootoosamy Cunoosamy
Published 2019-07-01

LFRET, a novel rapid assay for anti-tissue transglutaminase antibody detection.

by Juuso Rusanen, Anne Toivonen, Jussi Hepojoki, Satu Hepojoki, Pekka Arikoski, Markku Heikkinen, Outi Vaarala, Jorma Ilonen, Klaus Hedman
Published 2019-01-01

Altered activation of innate immunity associates with white matter volume and diffusion in first-episode psychosis.

by Teemu Mäntylä, Outi Mantere, Tuukka T Raij, Tuula Kieseppä, Hanna Laitinen, Jaana Leiviskä, Minna Torniainen, Lauri Tuominen, Outi Vaarala, Jaana Suvisaari
Published 2015-01-01

No evidence of autoimmunity to human OX1 or OX2 orexin receptors in Pandemrix-vaccinated narcoleptic children

by Krister Melén, Pinja Jalkanen, Jyrki P. Kukkonen, Markku Partinen, Hanna Nohynek, Arja Vuorela, Outi Vaarala, Tobias L. Freitag, Seppo Meri, Ilkka Julkunen
Published 2020-01-01

AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in Finland.

by Hanna Nohynek, Jukka Jokinen, Markku Partinen, Outi Vaarala, Turkka Kirjavainen, Jonas Sundman, Sari-Leena Himanen, Christer Hublin, Ilkka Julkunen, Päivi Olsén, Outi Saarenpää-Heikkilä, Terhi Kilpi
Published 2012-01-01

A MALT1 inhibitor suppresses human myeloid DC, effector T-cell and B-cell responses and retains Th1/regulatory T-cell homeostasis.

by Celine Dumont, Ulf Sivars, Theresa Andreasson, Lina Odqvist, Johan Mattsson, Amy DeMicco, Katerina Pardali, Gustav Johansson, Linda Yrlid, Rhona J Cox, Frank Seeliger, Marie Larsson, Ulf Gehrmann, Andrew M Davis, Outi Vaarala
Published 2020-01-01

Altered regulation and expression of genes by BET family of proteins in COPD patients.

by Rajneesh Malhotra, Nisha Kurian, Xiao-Hong Zhou, Fanyi Jiang, Susan Monkley, Amy DeMicco, Ib G Clausen, Göran Dellgren, Goran Edenro, Miika J Ahdesmäki, Maryam Clausen, Lisa Öberg, Elisabeth Israelsson, Graham Belfield, Outi Vaarala
Published 2017-01-01

No serological evidence of influenza A H1N1pdm09 virus infection as a contributing factor in childhood narcolepsy after Pandemrix vaccination campaign in Finland.

by Krister Melén, Markku Partinen, Janne Tynell, Maarit Sillanpää, Sari-Leena Himanen, Outi Saarenpää-Heikkilä, Christer Hublin, Päivi Olsen, Jorma Ilonen, Hanna Nohynek, Ritva Syrjänen, Terhi Kilpi, Arja Vuorela, Turkka Kirjavainen, Outi Vaarala, Ilkka Julkunen
Published 2013-01-01

Correction: Altered regulation and expression of genes by BET family of proteins in COPD patients.

by Rajneesh Malhotra, Nisha Kurian, Xiao-Hong Zhou, Fanyi Jiang, Susan Monkley, Amy DeMicco, Ib G Clausen, Göran Dellgren, Goran Edenro, Miika J Ahdesmäki, Maryam Clausen, Lisa Öberg, Elisabeth Israelsson, Graham Belfield, Outi Vaarala
Published 2017-01-01

Tissue Infiltrating LTi—Like Group 3 Innate Lymphoid Cells and T Follicular Helper Cells in Graves' and Hashimoto's Thyroiditis

by Audrey Mohr, Christophe Trésallet, Christophe Trésallet, Natacha Monot, Adeline Bauvois, Delphine Abiven, Muhammad Atif, Laetitia Claër, Rajneesh Malhotra, Gaëll Mayer, Robert Balderas, Outi Vaarala, Gabrielle Deniziaut, Isabelle Brocheriou, Camille Buffet, Laurence Leenhardt, Guy Gorochov, Makoto Miyara
Published 2020-04-01

Antigenic differences between AS03 adjuvanted influenza A (H1N1) pandemic vaccines: implications for pandemrix-associated narcolepsy risk.

by Outi Vaarala, Arja Vuorela, Markku Partinen, Marc Baumann, Tobias L Freitag, Seppo Meri, Päivi Saavalainen, Matti Jauhiainen, Rabah Soliymani, Turkka Kirjavainen, Päivi Olsen, Outi Saarenpää-Heikkilä, Juha Rouvinen, Merja Roivainen, Hanna Nohynek, Jukka Jokinen, Ilkka Julkunen, Terhi Kilpi
Published 2014-01-01

Fungal Dysbiosis and Intestinal Inflammation in Children With Beta-Cell Autoimmunity

by Jarno Honkanen, Arja Vuorela, Daniel Muthas, Laura Orivuori, Kristiina Luopajärvi, Mysore Vishakante Gowda Tejesvi, Anton Lavrinienko, Anton Lavrinienko, Anna Maria Pirttilä, Christopher L. Fogarty, Taina Härkönen, Taina Härkönen, Jorma Ilonen, Terhi Ruohtula, Mikael Knip, Mikael Knip, Janne J. Koskimäki, Outi Vaarala
Published 2020-03-01

Maturation of Gut Microbiota and Circulating Regulatory T Cells and Development of IgE Sensitization in Early Life

by Terhi Ruohtula, Marcus C. de Goffau, Janne K. Nieminen, Jarno Honkanen, Heli Siljander, Anu-Maaria Hämäläinen, Aleksandr Peet, Vallo Tillmann, Jorma Ilonen, Onni Niemelä, Gjalt W. Welling, Mikael Knip, Mikael Knip, Mikael Knip, Mikael Knip, Mikael Knip, Hermie J. Harmsen, Outi Vaarala
Published 2019-10-01

Predisposition to Childhood Otitis Media and Genetic Polymorphisms within the Toll-Like Receptor 4 (TLR4) Locus.

by Lena Hafrén, Elisabet Einarsdottir, Erna Kentala, Sari Hammarén-Malmi, Mahmood F Bhutta, Carol J MacArthur, Beth Wilmot, Margaretha Casselbrant, Yvette P Conley, Daniel E Weeks, Ellen M Mandel, Outi Vaarala, Anna Kallio, Merit Melin, Janne K Nieminen, Eira Leinonen, Juha Kere, Petri S Mattila
Published 2015-01-01

Associations Between Serum Fatty Acids and Immunological Markers in Children Developing Islet Autoimmunity—The TRIGR Nested Case–Control Study

by Sari Niinistö, Maija E. Miettinen, David Cuthbertson, Jarno Honkanen, Leena Hakola, Leena Hakola, Reija Autio, Iris Erlund, Petra Arohonka, Arja Vuorela, Taina Härkönen, Heikki Hyöty, Heikki Hyöty, Jeffrey P. Krischer, Outi Vaarala, Mikael Knip, Mikael Knip, Mikael Knip, Suvi M. Virtanen, Suvi M. Virtanen, Suvi M. Virtanen, Suvi M. Virtanen, TRIGR Investigators
Published 2022-05-01

Immunomodulatory Effects of Rhinovirus and Enterovirus Infections During the First Year of Life

by Terhi Ruohtula, Anita Kondrashova, Jussi Lehtonen, Sami Oikarinen, Anu-Maaria Hämäläinen, Onni Niemelä, Aleksandr Peet, Vallo Tillmann, Janne K. Nieminen, Jorma Ilonen, Mikael Knip, Mikael Knip, Mikael Knip, Mikael Knip, Outi Vaarala, Heikki Hyöty, Heikki Hyöty, the DIABIMMUNE Study Group, Mikael Knip, Taina Härkönen, Samppa Ryhänen, Heli Siljander, Katriina Koski, Matti Koski, Janne Nieminen, Terhi Ruohtula, Outi Vaarala, Onni Niemelä, Anu-Maaria Hämäläinen, Anne Ormisson, Aleksandr Peet, Vallo Tillmann, Valentina Ulich, Elena Kuzmicheva, Sergei Mokurov, Svetlana Markova, Svetlana Pylova, Marina Isakova, Elena Shakurova, Vladimir Petrov, Natalya V. Dorshakova, Tatyana Karapetyan, Tatyana Varlamova, Jorma Ilonen, Minna Kiviniemi, Kristi Alnek, Helis Janson, Raivo Uibo, Tiit Salum, Erika von Mutius, Juliane Weber, Helena Ahlfors, Henna Kallionpää, Essi Laajala, Riitta Lahesmaa, Harri Lähdesmäki, Robert Moulder, Heikki Hyöty, Hanna Honkanen, Anita Kondrashova, Sami Oikarinen, Hermie J. M. Harmsen, Marcus C. De Goffau, Gjalt Welling, Kirsi Alahuhta, Suvi M. Virtanen
Published 2021-02-01