Using a biologically annotated library to analyze the anticancer mechanism of serine palmitoyl transferase (SPT) inhibitors

by Osamu Sano, Ken‐ichi Kazetani, Ryutaro Adachi, Osamu Kurasawa, Tomohiro Kawamoto, Hidehisa Iwata
Published 2017-04-01

Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles

by Kentaro Otake, Keiko Adachi‐Tominari, Hiroaki Nagai, Masayo Saito, Osamu Sano, Yoshihiko Hirozane, Hidehisa Iwata
Published 2021-02-01

Sphingomyelin-dependence of cholesterol efflux mediated by ABCG1s⃞

by Osamu Sano, Aya Kobayashi, Kohjiro Nagao, Keigo Kumagai, Noriyuki Kioka, Kentaro Hanada, Kazumitsu Ueda, Michinori Matsuo
Published 2007-11-01

Feedback activation of AMPK-mediated autophagy acceleration is a key resistance mechanism against SCD1 inhibitor-induced cell growth inhibition.

by Akito Ono, Osamu Sano, Ken-Ichi Kazetani, Takamichi Muraki, Keisuke Imamura, Hiroyuki Sumi, Junji Matsui, Hidehisa Iwata
Published 2017-01-01

ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production.

by Osamu Sano, Maki Tsujita, Yuji Shimizu, Reiko Kato, Aya Kobayashi, Noriyuki Kioka, Alan T Remaley, Makoto Michikawa, Kazumitsu Ueda, Michinori Matsuo
Published 2016-01-01

ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane.

by Osamu Sano, Shiho Ito, Reiko Kato, Yuji Shimizu, Aya Kobayashi, Yasuhisa Kimura, Noriyuki Kioka, Kentaro Hanada, Kazumitsu Ueda, Michinori Matsuo
Published 2014-01-01

A Cell-Based High-Throughput Screening Identified Two Compounds that Enhance PINK1-Parkin Signaling

by Kahori Shiba-Fukushima, Tsuyoshi Inoshita, Osamu Sano, Hidehisa Iwata, Kei-ichi Ishikawa, Hideyuki Okano, Wado Akamatsu, Yuzuru Imai, Nobutaka Hattori
Published 2020-05-01

Synthetic mRNA‐based differentiation method enables early detection of Parkinson's phenotypes in neurons derived from Gaucher disease‐induced pluripotent stem cells

by Tomohiko Akiyama, Saeko Sato, Shigeru B. H. Ko, Osamu Sano, Sho Sato, Masayo Saito, Hiroaki Nagai, Minoru S. H. Ko, Hidehisa Iwata
Published 2021-04-01

Identification of hub molecules of FUS-ALS by Bayesian gene regulatory network analysis of iPSC model: iBRN

by Masahiro Nogami, Mitsuru Ishikawa, Atsushi Doi, Osamu Sano, Takefumi Sone, Tetsuya Akiyama, Masashi Aoki, Atsushi Nakanishi, Kazuhiro Ogi, Masato Yano, Hideyuki Okano
Published 2021-07-01

A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells

by Masahiro Wakita, Akiko Takahashi, Osamu Sano, Tze Mun Loo, Yoshinori Imai, Megumi Narukawa, Hidehisa Iwata, Tatsuyuki Matsudaira, Shimpei Kawamoto, Naoko Ohtani, Tamotsu Yoshimori, Eiji Hara
Published 2020-04-01

DNA damage stress-induced translocation of mutant FUS proteins into cytosolic granules and screening for translocation inhibitors

by Masahiro Nogami, Masahiro Nogami, Osamu Sano, Keiko Adachi-Tominari, Yoshika Hayakawa-Yano, Yoshika Hayakawa-Yano, Takako Furukawa, Hidehisa Iwata, Kazuhiro Ogi, Kazuhiro Ogi, Hideyuki Okano, Masato Yano, Masato Yano
Published 2022-12-01