Influence of the Tumor Microenvironment on NK Cell Function in Solid Tumors

by Ombretta Melaiu, Ombretta Melaiu, Valeria Lucarini, Loredana Cifaldi, Doriana Fruci
Published 2020-01-01

Editorial: Cell network in antitumor immunity of pediatric and adult solid tumors

by Silvia Pesce, Ombretta Melaiu
Published 2023-07-01

Targeting the antigen processing and presentation pathway to overcome resistance to immune checkpoint therapy

by Silvia D’Amico, Patrizia Tempora, Ombretta Melaiu, Ombretta Melaiu, Valeria Lucarini, Loredana Cifaldi, Loredana Cifaldi, Franco Locatelli, Franco Locatelli, Doriana Fruci
Published 2022-07-01

Two bullets in the gun: combining immunotherapy with chemotherapy to defeat neuroblastoma by targeting adrenergic-mesenchymal plasticity

by Silvia D’Amico, Patrizia Tempora, Paula Gragera, Kamila Król, Ombretta Melaiu, Ombretta Melaiu, Maria Antonietta De Ioris, Franco Locatelli, Franco Locatelli, Doriana Fruci
Published 2023-10-01

Impact of Natural Occurring <i>ERAP1</i> Single Nucleotide Polymorphisms within miRNA-Binding Sites on HCMV Infection

by Ombretta Melaiu, Silvia D’Amico, Patrizia Tempora, Valeria Lucarini, Doriana Fruci
Published 2020-08-01

The Multiple Roles of CD147 in the Development and Progression of Oral Squamous Cell Carcinoma: An Overview

by Giovanni Barillari, Ombretta Melaiu, Marco Gargari, Silvia Pomella, Roberto Bei, Vincenzo Campanella
Published 2022-07-01

Quantification of the Immune Content in Neuroblastoma: Deep Learning and Topological Data Analysis in Digital Pathology

by Nicole Bussola, Bruno Papa, Ombretta Melaiu, Aurora Castellano, Doriana Fruci, Giuseppe Jurman
Published 2021-08-01

Dendritic Cells: Behind the Scenes of T-Cell Infiltration into the Tumor Microenvironment

by Valeria Lucarini, Ombretta Melaiu, Patrizia Tempora, Silvia D’Amico, Franco Locatelli, Doriana Fruci
Published 2021-01-01

Identification of Overexpressed Genes in Malignant Pleural Mesothelioma

by Federica Morani, Luisa Bisceglia, Giulia Rosini, Luciano Mutti, Ombretta Melaiu, Stefano Landi, Federica Gemignani
Published 2021-03-01

ERAP1 and ERAP2 Enzymes: A Protective Shield for RAS against COVID-19?

by Silvia D’Amico, Patrizia Tempora, Valeria Lucarini, Ombretta Melaiu, Stefania Gaspari, Mattia Algeri, Doriana Fruci
Published 2021-02-01

DNA Damage Response Gene Signature as Potential Treatment Markers for Oral Squamous Cell Carcinoma

by Silvia Pomella, Matteo Cassandri, Ombretta Melaiu, Francesco Marampon, Marco Gargari, Vincenzo Campanella, Rossella Rota, Giovanni Barillari
Published 2023-01-01

DNAM-1 chimeric receptor-engineered NK cells: a new frontier for CAR-NK cell-based immunotherapy

by Loredana Cifaldi, Ombretta Melaiu, Roberto Giovannoni, Monica Benvenuto, Monica Benvenuto, Chiara Focaccetti, Daniela Nardozi, Giovanni Barillari, Roberto Bei
Published 2023-06-01

The Combination of Bioavailable Concentrations of Curcumin and Resveratrol Shapes Immune Responses While Retaining the Ability to Reduce Cancer Cell Survival

by Chiara Focaccetti, Camilla Palumbo, Monica Benvenuto, Raffaele Carrano, Ombretta Melaiu, Daniela Nardozi, Valentina Angiolini, Valeria Lucarini, Bora Kërpi, Laura Masuelli, Loredana Cifaldi, Roberto Bei
Published 2023-12-01

MYCN is an immunosuppressive oncogene dampening the expression of ligands for NK-cell-activating receptors in human high-risk neuroblastoma

by Elisa Brandetti, Irene Veneziani, Ombretta Melaiu, Annalisa Pezzolo, Aurora Castellano, Renata Boldrini, Elisa Ferretti, Doriana Fruci, Lorenzo Moretta, Vito Pistoia, Franco Locatelli, Loredana Cifaldi
Published 2017-06-01

The Combination of Immune Checkpoint Blockade with Tumor Vessel Normalization as a Promising Therapeutic Strategy for Breast Cancer: An Overview of Preclinical and Clinical Studies

by Ombretta Melaiu, Gianluca Vanni, Ilaria Portarena, Chiara Adriana Pistolese, Lucia Anemona, Silvia Pomella, Roberto Bei, Oreste Claudio Buonomo, Mario Roselli, Alessandro Mauriello, Giovanni Barillari
Published 2023-02-01

Correction: MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma.

by Ombretta Melaiu, Justin Stebbing, Ylenia Lombardo, Elisa Bracci, Norihisa Uehara, Alessandra Bonotti, Alfonso Cristaudo, Rudy Foddis, Luciano Mutti, Roberto Barale, Federica Gemignani, Georgios Giamas, Stefano Landi
Published 2017-01-01

MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma.

by Ombretta Melaiu, Justin Stebbing, Ylenia Lombardo, Elisa Bracci, Norihisa Uehara, Alessandra Bonotti, Alfonso Cristaudo, Rudy Foddis, Luciano Mutti, Roberto Barale, Federica Gemignani, Georgios Giamas, Stefano Landi
Published 2014-01-01

Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma

by Ombretta Melaiu, Marco Chierici, Valeria Lucarini, Giuseppe Jurman, Libenzio Adrian Conti, Rita De Vito, Renata Boldrini, Loredana Cifaldi, Aurora Castellano, Cesare Furlanello, Vincenzo Barnaba, Franco Locatelli, Doriana Fruci
Published 2020-11-01

ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function

by Silvia D’Amico, Valerio D’Alicandro, Mirco Compagnone, Patrizia Tempora, Giusy Guida, Paolo Romania, Valeria Lucarini, Ombretta Melaiu, Michela Falco, Mattia Algeri, Daniela Pende, Loredana Cifaldi, Loredana Cifaldi, Doriana Fruci
Published 2021-11-01

Tumor-infiltrating T cells and PD-L1 expression in childhood malignant extracranial germ-cell tumors

by Renata Boldrini, Maria Debora De Pasquale, Ombretta Melaiu, Marco Chierici, Giuseppe Jurman, Maria Chiara Benedetti, Nunzio C. Salfi, Aurora Castellano, Paola Collini, Cesare Furlanello, Vito Pistoia, Loredana Cifaldi, Monica Terenziani, Doriana Fruci
Published 2019-02-01