OmicsVolcano: Software for intuitive visualization and interactive exploration of high-throughput biological data

by Irina Kuznetsova, Artur Lugmayr, Oliver Rackham, Aleksandra Filipovska
Published 2021-03-01

CirGO: an alternative circular way of visualising gene ontology terms

by Irina Kuznetsova, Artur Lugmayr, Stefan J. Siira, Oliver Rackham, Aleksandra Filipovska
Published 2019-02-01

Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins

by Henrik Spåhr, Tiongsun Chia, James P. Lingford, Stefan J. Siira, Scott B. Cohen, Aleksandra Filipovska, Oliver Rackham
Published 2018-06-01

LRPPRC-mediated folding of the mitochondrial transcriptome

by Stefan J. Siira, Henrik Spåhr, Anne-Marie J. Shearwood, Benedetta Ruzzenente, Nils-Göran Larsson, Oliver Rackham, Aleksandra Filipovska
Published 2017-11-01

Mitochondrial gene expression is required for platelet function and blood clotting

by Tara R. Richman, Judith A. Ermer, Jessica Baker, Stefan J. Siira, Benjamin T. Kile, Matthew D. Linden, Oliver Rackham, Aleksandra Filipovska
Published 2023-11-01

Mapping of Mitochondrial RNA-Protein Interactions by Digital RNase Footprinting

by Ganqiang Liu, Timothy R. Mercer, Anne-Marie J. Shearwood, Stefan J. Siira, Moira E. Hibbs, John S. Mattick, Oliver Rackham, Aleksandra Filipovska
Published 2013-11-01

Stepwise maturation of the peptidyl transferase region of human mitoribosomes

by Tea Lenarčič, Mateusz Jaskolowski, Marc Leibundgut, Alain Scaiola, Tanja Schönhut, Martin Saurer, Richard G. Lee, Oliver Rackham, Aleksandra Filipovska, Nenad Ban
Published 2021-06-01

The FASTK family proteins fine-tune mitochondrial RNA processing

by Akira Ohkubo, Lindsey Van Haute, Danielle L. Rudler, Maike Stentenbach, Florian A. Steiner, Oliver Rackham, Michal Minczuk, Aleksandra Filipovska, Jean-Claude Martinou
Published 2021-11-01

The FASTK family proteins fine-tune mitochondrial RNA processing.

by Akira Ohkubo, Lindsey Van Haute, Danielle L Rudler, Maike Stentenbach, Florian A Steiner, Oliver Rackham, Michal Minczuk, Aleksandra Filipovska, Jean-Claude Martinou
Published 2021-11-01

Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction.

by Tara R Richman, Judith A Ermer, Stefan M K Davies, Kara L Perks, Helena M Viola, Anne-Marie J Shearwood, Livia C Hool, Oliver Rackham, Aleksandra Filipovska
Published 2015-03-01

Computationally designed hyperactive Cas9 enzymes

by Pascal D. Vos, Giulia Rossetti, Jessica L. Mantegna, Stefan J. Siira, Andrianto P. Gandadireja, Mitchell Bruce, Samuel A. Raven, Olga Khersonsky, Sarel J. Fleishman, Aleksandra Filipovska, Oliver Rackham
Published 2022-05-01

Multi‐omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer

by Maike Stentenbach, Judith A Ermer, Danielle L Rudler, Kara L Perks, Samuel A Raven, Richard G Lee, Tim McCubbin, Esteban Marcellin, Stefan J Siira, Oliver Rackham, Aleksandra Filipovska
Published 2023-06-01

Copy number variation in tRNA isodecoder genes impairs mammalian development and balanced translation

by Laetitia A. Hughes, Danielle L. Rudler, Stefan J. Siira, Tim McCubbin, Samuel A. Raven, Jasmin M. Browne, Judith A. Ermer, Jeanette Rientjes, Jennifer Rodger, Esteban Marcellin, Oliver Rackham, Aleksandra Filipovska
Published 2023-04-01

Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice

by Tara R. Richman, Henrik Spåhr, Judith A. Ermer, Stefan M. K. Davies, Helena M. Viola, Kristyn A. Bates, John Papadimitriou, Livia C. Hool, Jennifer Rodger, Nils-Göran Larsson, Oliver Rackham, Aleksandra Filipovska
Published 2016-06-01

Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease.

by Nicola Ferreira, Christopher E Andoniou, Kara L Perks, Judith A Ermer, Danielle L Rudler, Giulia Rossetti, Ambika Periyakaruppiah, Jamie K Y Wong, Oliver Rackham, Peter G Noakes, Mariapia A Degli-Esposti, Aleksandra Filipovska
Published 2020-03-01

Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly

by Oliver Rackham, Jakob D. Busch, Stanka Matic, Stefan J. Siira, Irina Kuznetsova, Ilian Atanassov, Judith A. Ermer, Anne-Marie J. Shearwood, Tara R. Richman, James B. Stewart, Arnaud Mourier, Dusanka Milenkovic, Nils-Göran Larsson, Aleksandra Filipovska
Published 2016-08-01

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria

by Stanka Matic, Min Jiang, Thomas J. Nicholls, Jay P. Uhler, Caren Dirksen-Schwanenland, Paola Loguercio Polosa, Marie-Lune Simard, Xinping Li, Ilian Atanassov, Oliver Rackham, Aleksandra Filipovska, James B. Stewart, Maria Falkenberg, Nils-Göran Larsson, Dusanka Milenkovic
Published 2018-03-01

ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing

by Paula Clemente, Javier Calvo-Garrido, Sarah F. Pearce, Florian A. Schober, Megumi Shigematsu, Stefan J. Siira, Isabelle Laine, Henrik Spåhr, Christian Steinmetzger, Katja Petzold, Yohei Kirino, Rolf Wibom, Oliver Rackham, Aleksandra Filipovska, Joanna Rorbach, Christoph Freyer, Anna Wredenberg
Published 2022-09-01

PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly

by Kara L. Perks, Giulia Rossetti, Irina Kuznetsova, Laetitia A. Hughes, Judith A. Ermer, Nicola Ferreira, Jakob D. Busch, Danielle L. Rudler, Henrik Spahr, Thomas Schöndorf, Ann-Marie J. Shearwood, Helena M. Viola, Stefan J. Siira, Livia C. Hool, Dusanka Milenkovic, Nils-Göran Larsson, Oliver Rackham, Aleksandra Filipovska
Published 2018-04-01