Mutational effects of Cys113 on structural dynamics of Pin1

by Teikichi Ikura, Yasushige Yonezawa, Nobutoshi Ito
Published 2019-11-01

Coarse snapshots of oxygen-dissociation intermediates of a giant hemoglobin elucidated by determining the oxygen saturation in individual subunits in the crystalline state

by Nobutaka Numoto, Yoshiaki Kawano, Hideo Okumura, Seiki Baba, Yoshihiro Fukumori, Kunio Miki, Nobutoshi Ito
Published 2021-11-01

Crystal structures of complexes of vitamin D receptor ligand-binding domain with lithocholic acid derivatives

by Hiroyuki Masuno, Teikichi Ikura, Daisuke Morizono, Isamu Orita, Sachiko Yamada, Masato Shimizu, Nobutoshi Ito
Published 2013-08-01

High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28.

by Kunitake Higo, Teikichi Ikura, Masayuki Oda, Hisayuki Morii, Jun Takahashi, Ryo Abe, Nobutoshi Ito
Published 2013-01-01

Structures of oxygen dissociation intermediates of 400 kDa V2 hemoglobin provide coarse snapshots of the protein allostery

by Nobutaka Numoto, Seiko Onoda, Yoshiaki Kawano, Hideo Okumura, Seiki Baba, Yoshihiro Fukumori, Kunio Miki, Nobutoshi Ito
Published 2022-06-01

Structural and functional properties of Grb2 SH2 dimer in CD28 binding

by Yuhi Hosoe, Nobutaka Numoto, Satomi Inaba, Shuhei Ogawa, Hisayuki Morii, Ryo Abe, Nobutoshi Ito, Masayuki Oda
Published 2019-02-01

Lithocholic Acid Amides as Potent Vitamin D Receptor Agonists

by Ayana Yoshihara, Haru Kawasaki, Hiroyuki Masuno, Koki Takada, Nobutaka Numoto, Nobutoshi Ito, Naoya Hirata, Yasunari Kanda, Michiyasu Ishizawa, Makoto Makishima, Hiroyuki Kagechika, Aya Tanatani
Published 2022-01-01

Selective inhibition of the kinase DYRK1A by targeting its folding process

by Isao Kii, Yuto Sumida, Toshiyasu Goto, Rie Sonamoto, Yukiko Okuno, Suguru Yoshida, Tomoe Kato-Sumida, Yuka Koike, Minako Abe, Yosuke Nonaka, Teikichi Ikura, Nobutoshi Ito, Hiroshi Shibuya, Takamitsu Hosoya, Masatoshi Hagiwara
Published 2016-04-01

CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice

by Naoko Matsubara, Akihiro Imamura, Tatsuya Yonemizu, Chizuru Akatsu, Hongrui Yang, Akiharu Ueki, Natsuki Watanabe, Hajjaj Abdu-Allah, Nobutaka Numoto, Hiromu Takematsu, Shinobu Kitazume, Thomas F. Tedder, Jamey D. Marth, Nobutoshi Ito, Hiromune Ando, Hideharu Ishida, Hideharu Ishida, Makoto Kiso, Takeshi Tsubata
Published 2018-04-01

HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer’s disease pathology

by Hikari Tanaka, Kanoh Kondo, Kyota Fujita, Hidenori Homma, Kazuhiko Tagawa, Xiaocen Jin, Meihua Jin, Yuki Yoshioka, Sumire Takayama, Hitomi Masuda, Rie Tokuyama, Yukoh Nakazaki, Takashi Saito, Takaomi Saido, Shigeo Murayama, Teikichi Ikura, Nobutoshi Ito, Yu Yamamori, Kentaro Tomii, Marco E. Bianchi, Hitoshi Okazawa
Published 2021-10-01