Taming Parasites by Tailoring Them

by Bingjian Ren, Nishith Gupta
Published 2017-07-01

Phosphatidylthreonine: An exclusive phospholipid regulating calcium homeostasis and virulence in a parasitic protist

by Ruben D. Arroyo-Olarte, Nishith Gupta
Published 2016-05-01

H11-induced immunoprotection is predominantly linked to N-glycan moieties during Haemonchus contortus infection

by Chunqun Wang, Lu Liu, Tianjiao Wang, Xin Liu, Wenjie Peng, Ratnesh Kumar Srivastav, Xing-Quan Zhu, Nishith Gupta, Nishith Gupta, Nishith Gupta, Robin B. Gasser, Min Hu
Published 2022-10-01

A novel BR-SMAD is required for larval development in barber’s pole worm Haemonchus contortus

by Fangfang Li, Peixi Qin, Lisha Ye, Nishith Gupta, Min Hu
Published 2020-12-01

The protozoan parasite Toxoplasma gondii encodes a gamut of phosphodiesterases during its lytic cycle in human cells

by Kim Chi Vo, Özlem Günay-Esiyok, Nicolas Liem, Nishith Gupta
Published 2020-01-01

AP2XII-1 is a negative regulator of merogony and presexual commitment in Toxoplasma gondii

by Fuqiang Fan, Lilan Xue, Xiaoyan Yin, Nishith Gupta, Bang Shen
Published 2023-10-01

Illuminating pathogen-host intimacy through optogenetics.

by Ruben Dario Arroyo-Olarte, Laura Thurow, Vera Kozjak-Pavlovic, Nishith Gupta
Published 2018-07-01

Phosphatidylinositol synthesis, its selective salvage, and inter-regulation of anionic phospholipids in Toxoplasma gondii

by Bingjian Ren, Pengfei Kong, Fatima Hedar, Jos F. Brouwers, Nishith Gupta
Published 2020-12-01

A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii

by Heidy Y. Narvaez-Ortiz, Andrea J. Lopez, Nishith Gupta, Barbara H. Zimmermann
Published 2018-03-01

Optogenetic monitoring identifies phosphatidylthreonine-regulated calcium homeostasis in Toxoplasma gondii

by Arunakar Kuchipudi, Ruben D. Arroyo-Olarte, Friederike Hoffmann, Volker Brinkmann, Nishith Gupta
Published 2016-05-01

Apically-located P4-ATPase1-Lem1 complex internalizes phosphatidylserine and regulates motility-dependent invasion and egress in Toxoplasma gondii

by Kai Chen, Xiyu Huang, Ute Distler, Stefan Tenzer, Özlem Günay-Esiyok, Nishith Gupta
Published 2023-01-01

Synthesis vs. salvage of ester- and ether-linked phosphatidylethanolamine in the intracellular protozoan pathogen Toxoplasma gondii

by Bingjian Ren, Xiaohan Liang, Jos F. Brouwers, Rosalba Cruz Miron, Bang Shen, Nishith Gupta
Published 2023-03-01

Toxoplasma and Eimeria co-opt the host cFos expression for intracellular development in mammalian cells

by Bingjian Ren, Manuela Schmid, Mattea Scheiner, Hans-Joachim Mollenkopf, Richard Lucius, Emanuel Heitlinger, Nishith Gupta
Published 2021-01-01

Metabolic flexibilities and vulnerabilities in the pentose phosphate pathway of the zoonotic pathogen Toxoplasma gondii.

by Ningbo Xia, Xuefang Guo, Qinghong Guo, Nishith Gupta, Nuo Ji, Bang Shen, Lihua Xiao, Yaoyu Feng
Published 2022-09-01

N-glycome and N-glycoproteome of a hematophagous parasitic nematode Haemonchus

by Chunqun Wang, Wenjie Gao, Shi Yan, Xing-Quan Zhu, Xun Suo, Xin Liu, Nishith Gupta, Min Hu
Published 2021-01-01

Phosphatidylserine synthase in the endoplasmic reticulum of Toxoplasma is essential for its lytic cycle in human cells

by Dimitrios Alexandros Katelas, Rosalba Cruz-Miron, Ruben D. Arroyo-Olarte, Jos F. Brouwers, Ratnesh Kumar Srivastav, Nishith Gupta
Published 2024-06-01

Metabolic plasticity, essentiality and therapeutic potential of ribose-5-phosphate synthesis in Toxoplasma gondii

by Xuefang Guo, Nuo Ji, Qinghong Guo, Mengting Wang, Huiyu Du, Jiajia Pan, Lihua Xiao, Nishith Gupta, Yaoyu Feng, Ningbo Xia
Published 2024-04-01

Plasticity and therapeutic potential of cAMP and cGMP-specific phosphodiesterases in Toxoplasma gondii

by Kim Chi Vo, Liberta Ruga, Olympia Ekaterini Psathaki, Rico Franzkoch, Ute Distler, Stefan Tenzer, Michael Hensel, Peter Hegemann, Nishith Gupta
Published 2022-01-01

Phosphatidylthreonine and Lipid-Mediated Control of Parasite Virulence.

by Ruben D Arroyo-Olarte, Jos F Brouwers, Arunakar Kuchipudi, J Bernd Helms, Aindrila Biswas, Ildiko R Dunay, Richard Lucius, Nishith Gupta
Published 2015-01-01

Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in <named-content content-type="genus-species">Toxoplasma gondii</named-content>

by Ningbo Xia, Shu Ye, Xiaohan Liang, Pu Chen, Yanqin Zhou, Rui Fang, Junlong Zhao, Nishith Gupta, Shuzhen Yang, Jing Yuan, Bang Shen
Published 2019-06-01