Immune interface interference vaccines: An evolution‐informed approach to anti‐bacterial vaccine design

by Nicholas J. Croucher
Published 2024-03-01

The Emergence of Bacterial “Hopeful Monsters”

by Nicholas J. Croucher, Keith P. Klugman
Published 2014-08-01

Analysing pneumococcal invasiveness using Bayesian models of pathogen progression rates.

by Alessandra Løchen, James E Truscott, Nicholas J Croucher
Published 2022-02-01

A high-resolution view of genome-wide pneumococcal transformation.

by Nicholas J Croucher, Simon R Harris, Lars Barquist, Julian Parkhill, Stephen D Bentley
Published 2012-01-01

Synergistic Activity of Mobile Genetic Element Defences in <i>Streptococcus pneumoniae</i>

by Min Jung Kwun, Marco R. Oggioni, Stephen D. Bentley, Christophe Fraser, Nicholas J. Croucher
Published 2019-09-01

Horizontal DNA Transfer Mechanisms of Bacteria as Weapons of Intragenomic Conflict.

by Nicholas J Croucher, Rafal Mostowy, Christopher Wymant, Paul Turner, Stephen D Bentley, Christophe Fraser
Published 2016-03-01

Peptide Occurring in Enterobacteriaceae Triggers Streptococcus pneumoniae Cell Death

by Fauzy Nasher, Fauzy Nasher, Min Jung Kwun, Nicholas J. Croucher, Manfred Heller, Lucy J. Hathaway
Published 2019-09-01

Heterogeneity in the frequency and characteristics of homologous recombination in pneumococcal evolution.

by Rafal Mostowy, Nicholas J Croucher, William P Hanage, Simon R Harris, Stephen Bentley, Christophe Fraser
Published 2014-05-01

Genome-wide identification of lineage and locus specific variation associated with pneumococcal carriage duration

by John A Lees, Nicholas J Croucher, David Goldblatt, François Nosten, Julian Parkhill, Claudia Turner, Paul Turner, Stephen D Bentley
Published 2017-07-01

Selective and genetic constraints on pneumococcal serotype switching.

by Nicholas J Croucher, Lisa Kagedan, Claudette M Thompson, Julian Parkhill, Stephen D Bentley, Jonathan A Finkelstein, Marc Lipsitch, William P Hanage
Published 2015-03-01

Diversification of Colonization Factors in a Multidrug-Resistant <named-content content-type="genus-species">Escherichia coli</named-content> Lineage Evolving under Negative Freque...

by Alan McNally, Teemu Kallonen, Christopher Connor, Khalil Abudahab, David M. Aanensen, Carolyne Horner, Sharon J. Peacock, Julian Parkhill, Nicholas J. Croucher, Jukka Corander
Published 2019-04-01

Pneumococcal capsule expression is controlled through a conserved, distal cis-regulatory element during infection.

by David G Glanville, Ozcan Gazioglu, Michela Marra, Valerie L Tokars, Tatyana Kushnir, Medhanie Habtom, Nicholas J Croucher, Yaffa Mizrachi Nebenzahl, Alfonso Mondragón, Hasan Yesilkaya, Andrew T Ulijasz
Published 2023-01-01

Pneumococcal capsule expression is controlled through a conserved, distal cis-regulatory element during infection

by David G. Glanville, Ozcan Gazioglu, Michela Marra, Valerie L. Tokars, Tatyana Kushnir, Medhanie Habtom, Nicholas J. Croucher, Yaffa Mizrachi Nebenzahl, Alfonso Mondragón, Hasan Yesilkaya, Andrew T. Ulijasz
Published 2023-01-01

Sequence-based analysis uncovers an abundance of non-coding RNA in the total transcriptome of Mycobacterium tuberculosis.

by Kristine B Arnvig, Iñaki Comas, Nicholas R Thomson, Joanna Houghton, Helena I Boshoff, Nicholas J Croucher, Graham Rose, Timothy T Perkins, Julian Parkhill, Gordon Dougan, Douglas B Young
Published 2011-11-01

Post-vaccine epidemiology of serotype 3 pneumococci identifies transformation inhibition through prophage-driven alteration of a non-coding RNA

by Min Jung Kwun, Alexandru V. Ion, Hsueh-Chien Cheng, Joshua C. D’Aeth, Sam Dougan, Marco R. Oggioni, David A. Goulding, Stephen D. Bentley, Nicholas J. Croucher
Published 2022-12-01

Lineage-specific Virulence Determinants of Haemophilus influenzae Biogroup aegyptius

by Fiona R. Strouts, Peter Power, Nicholas J. Croucher, Nicola Corton, Andries van Tonder, Michael A. Quail, Paul R. Langford, Michael J. Hudson, Julian Parkhill, J. Simon Kroll, Stephen D. Bentley
Published 2012-03-01

Genomic and panproteomic analysis of the development of infant immune responses to antigenically-diverse pneumococci

by Nicholas J. Croucher, Joseph J. Campo, Timothy Q. Le, Jozelyn V. Pablo, Christopher Hung, Andy A. Teng, Claudia Turner, François Nosten, Stephen D. Bentley, Xiaowu Liang, Paul Turner, David Goldblatt
Published 2024-01-01

AmiA and AliA peptide ligands, found in Klebsiella pneumoniae, are imported into pneumococci and alter the transcriptome

by Janine Lux, Lucía Sánchez García, Patricia Chaparro Fernández, Laura Laloli, Manon F. Licheri, Clement Gallay, Peter W. M. Hermans, Nicholas J. Croucher, Jan-Willem Veening, Ronald Dijkman, Daniel Straume, Lucy J. Hathaway
Published 2024-05-01

Comprehensive identification of single nucleotide polymorphisms associated with beta-lactam resistance within pneumococcal mosaic genes.

by Claire Chewapreecha, Pekka Marttinen, Nicholas J Croucher, Susannah J Salter, Simon R Harris, Alison E Mather, William P Hanage, David Goldblatt, Francois H Nosten, Claudia Turner, Paul Turner, Stephen D Bentley, Julian Parkhill
Published 2014-08-01

Panproteome-wide analysis of antibody responses to whole cell pneumococcal vaccination

by Joseph J Campo, Timothy Q Le, Jozelyn V Pablo, Christopher Hung, Andy A Teng, Hervé Tettelin, Andrea Tate, William P Hanage, Mark R Alderson, Xiaowu Liang, Richard Malley, Marc Lipsitch, Nicholas J Croucher
Published 2018-12-01