Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect.

by Yijun Chen, Rob Cairns, Ioanna Papandreou, Albert Koong, Nicholas C Denko
Published 2009-09-01

Dynamic regulation of mitochondrial pyruvate metabolism is necessary for orthotopic pancreatic tumor growth

by Nancy P. Echeverri Ruiz, Vijay Mohan, Jinghai Wu, Sabina Scott, McKenzie Kreamer, Martin Benej, Tereza Golias, Ioanna Papandreou, Nicholas C. Denko
Published 2021-11-01

Pharmacological Regulation of Tumor Hypoxia in Model Murine Tumors and Spontaneous Canine Tumors

by Martin Benej, Jinghai Wu, McKenzie Kreamer, Martin Kery, Sergio Corrales-Guerrero, Ioanna Papandreou, Terence M. Williams, Zihai Li, Edward E. Graves, Laura E. Selmic, Nicholas C. Denko
Published 2021-04-01

The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways.

by Donald Courter, Hongbin Cao, Shirley Kwok, Christina Kong, Alice Banh, Peiwen Kuo, Donna M Bouley, Carmen Vice, Odd Terje Brustugun, Nicholas C Denko, Albert C Koong, Amato Giaccia, Quynh-Thu Le
Published 2010-03-01

CA IX Stabilizes Intracellular pH to Maintain Metabolic Reprogramming and Proliferation in Hypoxia

by Martin Benej, Martin Benej, Eliska Svastova, Radivojka Banova, Juraj Kopacek, Adriana Gibadulinova, Martin Kery, Simona Arena, Andrea Scaloni, Monica Vitale, Monica Vitale, Nicola Zambrano, Nicola Zambrano, Ioanna Papandreou, Nicholas C. Denko, Silvia Pastorekova
Published 2020-09-01

Slit2-Mediated Metabolic Reprogramming in Bone Marrow-Derived Macrophages Enhances Antitumor Immunity

by Kirti Kaul, Kirti Kaul, Martin Benej, Sanjay Mishra, Sanjay Mishra, Dinesh K. Ahirwar, Dinesh K. Ahirwar, Marshleen Yadav, Marshleen Yadav, Kristin I. Stanford, Naduparambil K. Jacob, Naduparambil K. Jacob, Nicholas C. Denko, Ramesh K. Ganju, Ramesh K. Ganju
Published 2021-10-01

Association between Tumor Microbiome and Hypoxia across Anatomic Subsites of Head and Neck Cancers

by Aastha Dhakal, Rituraj Upadhyay, Caroline Wheeler, Rebecca Hoyd, Vidhya Karivedu, Mauricio E. Gamez, Sasha Valentin, Meade Vanputten, Priyanka Bhateja, Marcelo Bonomi, David J. Konieczkowski, Sujith Baliga, Darrion L. Mitchell, John C. Grecula, Dukagjin M. Blakaj, Nicholas C. Denko, Sachin R. Jhawar, Daniel Spakowicz
Published 2022-12-01

Comparative analysis of the tumor microbiome, molecular profiles, and immune cell abundances by HPV status in mucosal head and neck cancers and their impact on survival

by Rituraj Upadhyay, Aastha Dhakal, Caroline Wheeler, Rebecca Hoyd, Malvenderjit Jagjit Singh, Vidhya Karivedu, Priyanka Bhateja, Marcelo Bonomi, Sasha Valentin, Mauricio E. Gamez, David J. Konieczkowski, Sujith Baliga, John C. Grecula, Dukagjin M. Blakaj, Emile Gogineni, Darrion L. Mitchell, Nicholas C. Denko, Daniel Spakowicz, Sachin R. Jhawar
Published 2024-12-01