Immunobiology of Steroid-Unresponsive Severe Asthma

by Courtney Lynn Marshall, Courtney Lynn Marshall, Kosovare Hasani, Neeloffer Mookherjee, Neeloffer Mookherjee
Published 2021-08-01

Host Defense Peptide LL-37-Mediated Chemoattractant Properties, but Not Anti-Inflammatory Cytokine IL-1RA Production, Is Selectively Controlled by Cdc42 Rho GTPase via G Protein-Co...

by Mahadevappa Hemshekhar, Ka-Yee Grace Choi, Ka-Yee Grace Choi, Neeloffer Mookherjee, Neeloffer Mookherjee
Published 2018-08-01

Functions of Cationic Host Defense Peptides in Immunity

by Mahadevappa Hemshekhar, Vidyanand Anaparti, Neeloffer Mookherjee
Published 2016-07-01

Ultrashort cationic lipopeptides and lipopeptoids selectively induce cytokine production in macrophages.

by Brandon Findlay, Neeloffer Mookherjee, Frank Schweizer
Published 2013-01-01

Cathelicidin and Calprotectin Are Disparately Altered in Murine Models of Inflammatory Arthritis and Airway Inflammation

by Mahadevappa Hemshekhar, Hadeesha Piyadasa, Hadeesha Piyadasa, Dina Mostafa, Dina Mostafa, Leola N. Y. Chow, Andrew J. Halayko, Andrew J. Halayko, Neeloffer Mookherjee, Neeloffer Mookherjee, Neeloffer Mookherjee
Published 2020-08-01

Buprenorphine Alters Inflammatory and Oxidative Stress Molecular Markers in Arthritis

by Mahadevappa Hemshekhar, Vidyanand Anaparti, Carol Hitchon, Neeloffer Mookherjee
Published 2017-01-01

A bioavailable form of curcumin suppresses cationic host defence peptides cathelicidin and calprotectin in a murine model of collagen-induced arthritis

by Mahadevappa Hemshekhar, Dylan Lloyd, Hani El-Gabalawy, Neeloffer Mookherjee
Published 2023-09-01

A bioavailable form of curcumin, in combination with vitamin-D- and omega-3-enriched diet, modifies disease onset and outcomes in a murine model of collagen-induced arthritis

by Mahadevappa Hemshekhar, Vidyanand Anaparti, Hani El-Gabalawy, Neeloffer Mookherjee
Published 2021-01-01

Cytokines IL-17, TNF and IFN-γ Alter the Expression of Antimicrobial Peptides and Proteins Disparately: A Targeted Proteomics Analysis using SOMAscan Technology

by Anthony Altieri, Hadeesha Piyadasa, Breann Recksiedler, Victor Spicer, Neeloffer Mookherjee
Published 2018-08-01

Sex Dimorphism of Allergen-Induced Secreted Proteins in Murine and Human Lungs

by Mahadevappa Hemshekhar, Dina H. D. Mostafa, Dina H. D. Mostafa, Victor Spicer, Hadeesha Piyadasa, Hadeesha Piyadasa, Hadeesha Piyadasa, Danay Maestre-Batlle, Anette K. Bolling, Anette K. Bolling, Andrew J. Halayko, Andrew J. Halayko, Christopher Carlsten, Neeloffer Mookherjee, Neeloffer Mookherjee, Neeloffer Mookherjee
Published 2022-06-01

Immunomodulatory Functions of the Human Cathelicidin LL-37 (aa 13–31)-Derived Peptides are Associated with Predicted α-Helical Propensity and Hydrophobic Index

by Mahadevappa Hemshekhar, Sana Faiyaz, Ka-Yee Grace Choi, Oleg V. Krokhin, Neeloffer Mookherjee
Published 2019-09-01

Circulating levels of free 25(OH)D increase at the onset of rheumatoid arthritis.

by Vidyanand Anaparti, Xiaobo Meng, Mahadevappa Hemshekhar, Irene Smolik, Neeloffer Mookherjee, Hani El-Gabalawy
Published 2019-01-01

Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects

by Vidyanand Anaparti, Irene Smolik, Xiaobo Meng, Victor Spicer, Neeloffer Mookherjee, Hani El-Gabalawy
Published 2017-11-01

Biosignature for airway inflammation in a house dust mite-challenged murine model of allergic asthma

by Hadeesha Piyadasa, Anthony Altieri, Sujata Basu, Jacquie Schwartz, Andrew J. Halayko, Neeloffer Mookherjee
Published 2016-02-01

Effect of vitamin D supplementation on Mycobacterium tuberculosis-induced innate immune responses in a Canadian Dené First Nations cohort.

by Linda Larcombe, Pamela Orr, Emily Turner-Brannen, Caroline R Slivinski, Peter W Nickerson, Neeloffer Mookherjee
Published 2012-01-01

Overexpression of the Small RNA PA0805.1 in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Modulates the Expression of a Large Set of Genes and...

by Shannon R. Coleman, Maren L. Smith, Victor Spicer, Ying Lao, Neeloffer Mookherjee, Robert E. W. Hancock
Published 2020-06-01

Characterization of sex-related differences in allergen house dust mite-challenged airway inflammation, in two different strains of mice

by Dina H. D. Mostafa, Mahadevappa Hemshekhar, Hadeesha Piyadasa, Anthony Altieri, Andrew J. Halayko, Christopher D. Pascoe, Neeloffer Mookherjee
Published 2022-12-01

Combination of IL-17A/F and TNF-α uniquely alters the bronchial epithelial cell proteome to enhance proteins that augment neutrophil migration

by Anthony Altieri, Hadeesha Piyadasa, Mahadevappa Hemshekhar, Natasha Osawa, Breann Recksiedler, Victor Spicer, Pieter S Hiemstra, Andrew J Halayko, Neeloffer Mookherjee
Published 2022-12-01

Human Host Defense Peptide LL-37 Suppresses TNFα-Mediated Matrix Metalloproteinases MMP9 and MMP13 in Human Bronchial Epithelial Cells

by Anthony Altieri, Courtney Lynn Marshall, Padmanie Ramotar, Dylan Lloyd, Mahadevappa Hemshekhar, Victor Spicer, Anne M. van der Does, Neeloffer Mookherjee
Published 2024-03-01

Integrating Proteomes for Lung Tissues and Lavage Reveals Pathways That Link Responses in Allergen-Challenged Mice

by Thomas H. Mahood, Christopher D. Pascoe, Tobias K. Karakach, Aruni Jha, Sujata Basu, Peyman Ezzati, Victor Spicer, Neeloffer Mookherjee, Andrew J. Halayko
Published 2021-01-01