Iron Deficiency without Anemia Decreases Physical Endurance and Mitochondrial Complex I Activity of Oxidative Skeletal Muscle in the Mouse

by Emmanuel Rineau, Naïg Gueguen, Vincent Procaccio, Franck Geneviève, Pascal Reynier, Daniel Henrion, Sigismond Lasocki
Published 2021-03-01

Case report: Thirty-year progression of an EMPF1 encephalopathy due to defective mitochondrial and peroxisomal fission caused by a novel de novo heterozygous DNM1L variant

by Charlène Lhuissier, Bart E. Wagner, Amy Vincent, Gaëtan Garraux, Gaëtan Garraux, Olivier Hougrand, Rudy Van Coster, Valerie Benoit, Deniz Karadurmus, Guy Lenaers, Guy Lenaers, Naïg Gueguen, Naïg Gueguen, Arnaud Chevrollier, Isabelle Maystadt, Isabelle Maystadt
Published 2022-09-01

Overexpression of the mitochondrial T3 receptor p43 induces a shift in skeletal muscle fiber types.

by François Casas, Laurence Pessemesse, Stéphanie Grandemange, Pascal Seyer, Naïg Gueguen, Olivier Baris, Laurence Lepourry, Gérard Cabello, Chantal Wrutniak-Cabello
Published 2008-01-01

Estrogen-related receptor alpha modulates lactate dehydrogenase activity in thyroid tumors.

by Delphine Mirebeau-Prunier, Soazig Le Pennec, Caroline Jacques, Jean-Fred Fontaine, Naig Gueguen, Nathalie Boutet-Bouzamondo, Audrey Donnart, Yves Malthièry, Frédérique Savagner
Published 2013-01-01

Mitochondrial F0F1-ATP synthase governs the induction of mitochondrial fission

by Charlène Lhuissier, Valérie Desquiret-Dumas, Anaïs Girona, Jennifer Alban, Justine Faure, Julien Cassereau, Philippe Codron, Guy Lenaers, Olivier R. Baris, Naïg Gueguen, Arnaud Chevrollier
Published 2024-05-01

Doxorubicin-Induced Autophagolysosome Formation Is Partly Prevented by Mitochondrial ROS Elimination in DOX-Resistant Breast Cancer Cells

by Seyedeh Tayebeh Ahmadpour, Valérie Desquiret-Dumas, Ulku Yikilmaz, Julie Dartier, Isabelle Domingo, Celine Wetterwald, Charlotte Orre, Naïg Gueguen, Lucie Brisson, Karine Mahéo, Jean-François Dumas
Published 2021-08-01

Overexpression of the mitochondrial T3 receptor induces skeletal muscle atrophy during aging.

by François Casas, Laurence Pessemesse, Stéphanie Grandemange, Pascal Seyer, Olivier Baris, Naïg Gueguen, Christelle Ramonatxo, Florence Perrin, Gilles Fouret, Laurence Lepourry, Gérard Cabello, Chantal Wrutniak-Cabello
Published 2009-05-01

Resveratrol Directly Binds to Mitochondrial Complex I and Increases Oxidative Stress in Brain Mitochondria of Aged Mice.

by Naïg Gueguen, Valérie Desquiret-Dumas, Géraldine Leman, Stéphanie Chupin, Stéphanie Baron, Valérie Nivet-Antoine, Emilie Vessières, Audrey Ayer, Daniel Henrion, Guy Lenaers, Pascal Reynier, Vincent Procaccio
Published 2015-01-01

A Mitochondria-Specific Isoform of FASTK Is Present In Mitochondrial RNA Granules and Regulates Gene Expression and Function

by Alexis A. Jourdain, Mirko Koppen, Christopher D. Rodley, Kinsey Maundrell, Naïg Gueguen, Pascal Reynier, Adela M. Guaras, José A. Enriquez, Paul Anderson, Maria Simarro, Jean-Claude Martinou
Published 2015-02-01

The Long Non-Coding RNA SAMMSON Is a Regulator of Chemosensitivity and Metabolic Orientation in MCF-7 Doxorubicin-Resistant Breast Cancer Cells

by Charlotte Orre, Xavier Dieu, Jordan Guillon, Naïg Gueguen, Seyedeh Tayebeh Ahmadpour, Jean-François Dumas, Salim Khiati, Pascal Reynier, Guy Lenaers, Olivier Coqueret, Arnaud Chevrollier, Delphine Mirebeau-Prunier, Valérie Desquiret-Dumas
Published 2021-11-01

Acetoacetate protects macrophages from lactic acidosis-induced mitochondrial dysfunction by metabolic reprograming

by Clément Adam, Léa Paolini, Naïg Gueguen, Guillaume Mabilleau, Laurence Preisser, Simon Blanchard, Pascale Pignon, Florence Manero, Morgane Le Mao, Alain Morel, Pascal Reynier, Céline Beauvillain, Yves Delneste, Vincent Procaccio, Pascale Jeannin
Published 2021-12-01

Kynurenic Acid: A Novel Player in Cardioprotection against Myocardial Ischemia/Reperfusion Injuries

by Rima Kamel, Delphine Baetz, Naïg Gueguen, Lucie Lebeau, Agnès Barbelivien, Anne-Laure Guihot, Louwana Allawa, Jean Gallet, Justine Beaumont, Michel Ovize, Daniel Henrion, Pascal Reynier, Delphine Mirebeau-Prunier, Fabrice Prunier, Sophie Tamareille
Published 2023-09-01

Next-Generation Sequencing Identifies Novel <i>PMPCA</i> Variants in Patients with Late-Onset Dominant Optic Atrophy

by Majida Charif, Arnaud Chevrollier, Naïg Gueguen, Selma Kane, Céline Bris, David Goudenège, Valerie Desquiret-Dumas, Isabelle Meunier, Fanny Mochel, Luc Jeanjean, Fanny Varenne, Vincent Procaccio, Pascal Reynier, Dominique Bonneau, Patrizia Amati-Bonneau, Guy Lenaers
Published 2022-07-01

Increased Protein <i>S</i>-Glutathionylation in Leber’s Hereditary Optic Neuropathy (LHON)

by Lei Zhou, James Chun Yip Chan, Stephanie Chupin, Naïg Gueguen, Valérie Desquiret-Dumas, Siew Kwan Koh, Jianguo Li, Yan Gao, Lu Deng, Chandra Verma, Roger W Beuerman, Eric Chun Yong Chan, Dan Milea, Pascal Reynier
Published 2020-04-01

OPA1-related disorders: Diversity of clinical expression, modes of inheritance and pathophysiology

by Juan Manuel Chao de la Barca, Delphine Prunier-Mirebeau, Patrizia Amati-Bonneau, Marc Ferré, Emmanuelle Sarzi, Céline Bris, Stéphanie Leruez, Arnaud Chevrollier, Valérie Desquiret-Dumas, Naïg Gueguen, Christophe Verny, Christian Hamel, Dan Miléa, Vincent Procaccio, Dominique Bonneau, Guy Lenaers, Pascal Reynier
Published 2016-06-01

DRP1 haploinsufficiency attenuates cardiac ischemia/reperfusion injuries.

by Laura Bouche, Rima Kamel, Sophie Tamareille, Gabriel Garcia, Camille Villedieu, Bruno Pillot, Naïg Gueguen, Ahmad Chehaitly, Juan Manuel Chao de la Barca, Justine Beaumont, Delphine Baetz, Michel Ovize, Hiromi Sesaki, Daniel Henrion, Pascal Reynier, Guy Lenaers, Fabrice Prunier, Delphine Mirebeau-Prunier
Published 2021-01-01

Glutamate-Induced Deregulation of Krebs Cycle in Mitochondrial Encephalopathy Lactic Acidosis Syndrome Stroke-Like Episodes (MELAS) Syndrome Is Alleviated by Ketone Body Exposure

by Sophie Belal, David Goudenège, Cinzia Bocca, Florent Dumont, Juan Manuel Chao De La Barca, Valérie Desquiret-Dumas, Naïg Gueguen, Guillaume Geffroy, Rayane Benyahia, Selma Kane, Salim Khiati, Céline Bris, Tamas Aranyi, Daniel Stockholm, Aurore Inisan, Aurélie Renaud, Magalie Barth, Gilles Simard, Pascal Reynier, Franck Letournel, Guy Lenaers, Dominique Bonneau, Arnaud Chevrollier, Vincent Procaccio
Published 2022-07-01

Primary mitochondrial disorders and mimics: Insights from a large French cohort

by Cécile Rouzier, Emmanuelle Pion, Annabelle Chaussenot, Céline Bris, Samira Ait‐El‐Mkadem Saadi, Valérie Desquiret‐Dumas, Naïg Gueguen, Konstantina Fragaki, Patrizia Amati‐Bonneau, Giulia Barcia, Pauline Gaignard, Julie Steffann, Alessandra Pennisi, Jean‐Paul Bonnefont, Elise Lebigot, Sylvie Bannwarth, Bruno Francou, Benoit Rucheton, Damien Sternberg, Marie‐Laure Martin‐Negrier, Aurélien Trimouille, Gaëlle Hardy, Stéphane Allouche, Cécile Acquaviva‐Bourdain, Cécile Pagan, Anne‐Sophie Lebre, Pascal Reynier, Mireille Cossee, Shahram Attarian, Véronique Paquis‐Flucklinger, MitoDiag's Network Collaborators, Vincent Procaccio
Published 2024-06-01